@article{7f10478ddf684d73b0efe1616f606381,
title = "Cholesteric liquid crystal biosensor platform with image analysis for rapid detection of COVID-19",
abstract = "Rapid and low-cost diagnosis of coronavirus disease 2019 (COVID-19) is essential to identify infected subjects, particularly asymptomatic cases, primarily to arrest the spread of the disease through local transmission. Antibody-based chromatographic serological tests, as an alternative to the RT-PCR technique, offer only limited help due to high false positives. We propose to exploit our cholesteric liquid crystal biosensor platform for one-step, wash-free, rapid detection of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus directly with minimal sample pre-processing. As mentioned above, cholesteric liquid crystals are an effective and innovative approach to healthcare as a rapid test for the diagnosis of COVID-19 and other diseases.",
keywords = "biosensor, cholesteric liquid crystal, COVID-19, diagnosis, spike protein",
author = "Lin, {Ping Yuan} and Chung, {Yi Wei} and Chuang, {Er Yuan} and Wang, {Yen Chieh} and Lai, {Min Chih} and Hsu, {Yen Chin} and Lin, {Chun Che} and Hsiao, {Yu Cheng}",
note = "Funding Information: This research work was financially supported by grants from Taipei Medical University Hospital (109TMU-TMUH-02), Shuangho Hospital, Ministry of Health And Welfare (111FRP-06) and the Ministry of Science and Technology (MOST), Taiwan (MOST 108-2221-E-038-017-MY3, 109-2636-E-038-001, 111-2320-B-038-039, and 108-2320-B-038-061-MY3), University System of Taipei under grant number. USTP-NTUT-TMU-109-02. Publisher Copyright: Copyright {\textcopyright} 2023 Lin, Chung, Chuang, Wang, Lai, Hsu, Lin and Hsiao.",
year = "2023",
doi = "10.3389/fbioe.2023.1148446",
language = "English",
volume = "11",
journal = "Frontiers in Bioengineering and Biotechnology",
issn = "2296-4185",
publisher = "Frontiers Media SA",
}