Catheter-based neurosalvage for acute embolic complication during carotid intervention

Mao Shin Lin, Ying Hsien Chen, Chi Chao Chao, Cheng Hsin Lin, Hung Yuan Li, Chia Lun Chao, Ming Fong Chen, Hsien Li Kao

研究成果: 雜誌貢獻文章同行評審

5 引文 斯高帕斯(Scopus)


Objectives: Iatrogenic emboli may be released during carotid intervention, causing permanent neurologic complications and catastrophic outcomes. This article reports the procedural details and clinical results of our series of neurosalvage techniques to manage thromboembolic events during carotid procedures. Methods: Between March 2003 and December 2007, 342 patients (283 men, 72.1 ± 8.9 years old, 121 symptomatic) underwent percutaneous stent deployment in 407 cervical internal carotid arteries in our institution. Visible distal embolization with flow occlusion caused neurologic complications in 10 patients (2.5%), and a structured and stepwise neurosalvage approach was attempted. Results: Guidewire fragmentation and microcatheter injection of heparin and nitroglycerin were performed in all 10 patients as step 1. Intra-arterial thrombolysis was given in four patients and balloon angioplasty in five, as step 2. Intracranial stenting was done in one patient as the last step. Successful angiographic recanalization (Thrombolysis in Myocardial Infarction [TIMI] grade 2-3) occurred in 9 of 10 (90%). Residual neurologic sequel was observed in five, including three patients with hemorrhage complications (1 received emergent craniotomy). There was no neurologic mortality in this series. Conclusions: Acute embolic complication during carotid artery stenting can be managed by catheter-based neurosalvage with effective angiographic recanalization and marginal clinical success.

頁(從 - 到)308-313
期刊Journal of Vascular Surgery
出版狀態已發佈 - 8月 2010

ASJC Scopus subject areas

  • 心臟病學與心血管醫學
  • 手術


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