Cardiac nucleotide levels and mitochondrial respiration in copper-deficient rats

Jane C.J. Chao, Denis M. Medeiros, Ruth A. Altschuld, Charlene M. Hohl

研究成果: 雜誌貢獻文章同行評審

29 引文 斯高帕斯(Scopus)

摘要

1. 1. Male weanling Long-Evans rats were randomly assigned to either copper-adequate (6.0 mgCu/kg feed) or copper-deficient (<1.0 mg Cu/kg feed) diets for a 5 week period. 2. 2. Cardiac ATP levels and energy charges did not differ between the two groups. Levels of NAD and phosphocreatine as well as the sum of pyridine nucleotides were greater in copper-deficient rats compared with copper-adequate rats using HPLC analysis. 3. 3. Mitochondrial respiratory control ratios and oxygen consumption rates from copper-deficient rat hearts were depressed, although ADP:O ratios were similar to copper-adequate rat hearts.

原文英語
頁(從 - 到)163-168
頁數6
期刊Comparative Biochemistry and Physiology -- Part A: Physiology
104
發行號1
DOIs
出版狀態已發佈 - 1月 1993
對外發佈

ASJC Scopus subject areas

  • 生理學

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