Calculation of Bone Calcium Hydroxyapatite Concentration Using Abdomen Gemstone Spectral Imaging Computed Tomography in Taiwan

Yuan Chang, Chih-Kun Chang, Fei-Ting Hsu, Chi-Jen Chen, Ying-Chi Tseng, Kuo-Luon Kung, Tzung-Chi Huang

研究成果: 报告类型書籍


The decrease in the overall strength of the bone leads primarily to multi-site fracture and vertebral body fractures.Calcium hydroxyapatite was known to be a major component of bone mass, in order to measure accurate bone
density, the correspondence method need to be established. Currently, dual-energy X-ray absorptiometry (DXA)is the criterion standard for the evaluation of bone mineral density (BMD) in clinical, which used for bone density
estimation. However, two-dimensional image data may only provide the percentage of bone density but cannot represent the true value of the calcium content in bone region. Moreover, two-dimensional vertebrae images
must consider the error from other organizations. This error information will decrease the diagnostic accuracy of physician. Therefore, the goal of this study is to develop new methods to evaluate the concentration of CaHA in bone tissue, which could represent the major density of bone. Here, we used gemstone spectral imaging system to restructure abdomen dual-energy computed tomography (DECT) scan image from health patient, consequently; we may obtain three-dimensional images and substance calcium content of spine. In addition, the gemstone spectral imaging value obtained from the phantom study were further used for the conversion of CaHA concentration within participant sample spine.
出版狀態已發佈 - 8月 1 2018


  • Bone Density
  • DECT
  • Spine
  • Gemstone Spectral Imaging