Brugada syndrome in the elderly in Taiwan - Report of two cases

Brugada syndrome is a potentially lethal ventricular arrhythmia disease with an ECG pattern of ST-segment elevation in leads V1-3 and normal QT interval without structural heart disease. Clinical presentation of Brugada syndrome is characterized by a male predominance with syncope or sudden death, mostly at an average age of 40 years. We report 2 male patients, in whom the diagnosis was made at the ages of 71 and 74 years, respectively. They presented with aborted sudden death or repeated syncope. They had coved-type Brugada ECG, and one of them had positive procainamide provocative test. Both received implantation of a cardioverter defibrillator. One had recurrent events and received ICD discharge within 4 weeks after implantation. Our study showed that Brugada syndrome could occur in the elderly, and its clinical presentations were as severe as those in younger patients.