Bone loss in chronic kidney disease: Quantity or quality?

Cai Mei Zheng; Jin Quan Zheng; Chia Chao Wu; Chien Lin Lu; Jia Fwu Shyu; Hsu Yung-Ho; Mei Yi Wu; I. Jen Chiu; Yuan Hung Wang; Yuh Feng Lin; Kuo Cheng Lu

doi:10.1016/j.bone.2016.03.017

Bone loss in chronic kidney disease: Quantity or quality?

Cai Mei Zheng, Jin Quan Zheng, Chia Chao Wu, Chien Lin Lu, Jia Fwu Shyu, Hsu Yung-Ho, Mei Yi Wu, I. Jen Chiu, Yuan Hung Wang, Yuh Feng Lin, Kuo Cheng Lu

研究成果: 雜誌貢獻 › 回顧型文獻 › 同行評審

30 引文斯高帕斯（Scopus）

摘要

Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.

原文	英語
頁（從 - 到）	57-70
頁數	14
期刊	Bone
卷	87
DOIs	https://doi.org/10.1016/j.bone.2016.03.017
出版狀態	已發佈 - 6月 1 2016

ASJC Scopus subject areas

內分泌學、糖尿病和代謝
組織學
生理學

UN SDG

此研究成果有助於以下永續發展目標

存取文件

10.1016/j.bone.2016.03.017

其它文件與鏈接

Link to publication in Scopus

引用此

@article{fc7c7d96eda642a584734141a0416ef8,

title = "Bone loss in chronic kidney disease: Quantity or quality?",

abstract = "Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.",

keywords = "Bone quantity and bone quality losses, Bone remodeling, Chronic kidney disease-mineral bone disorder (CKD-MBD), Vitamin D therapy",

author = "Zheng, {Cai Mei} and Zheng, {Jin Quan} and Wu, {Chia Chao} and Lu, {Chien Lin} and Shyu, {Jia Fwu} and Hsu Yung-Ho and Wu, {Mei Yi} and Chiu, {I. Jen} and Wang, {Yuan Hung} and Lin, {Yuh Feng} and Lu, {Kuo Cheng}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = jun,

day = "1",

doi = "10.1016/j.bone.2016.03.017",

language = "English",

volume = "87",

pages = "57--70",

journal = "Bone",

issn = "8756-3282",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Bone loss in chronic kidney disease

T2 - Quantity or quality?

AU - Zheng, Cai Mei

AU - Zheng, Jin Quan

AU - Wu, Chia Chao

AU - Lu, Chien Lin

AU - Shyu, Jia Fwu

AU - Yung-Ho, Hsu

AU - Wu, Mei Yi

AU - Chiu, I. Jen

AU - Wang, Yuan Hung

AU - Lin, Yuh Feng

AU - Lu, Kuo Cheng

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.

AB - Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.

KW - Bone quantity and bone quality losses

KW - Bone remodeling

KW - Chronic kidney disease-mineral bone disorder (CKD-MBD)

KW - Vitamin D therapy

UR - http://www.scopus.com/inward/record.url?scp=84962633686&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84962633686&partnerID=8YFLogxK

U2 - 10.1016/j.bone.2016.03.017

DO - 10.1016/j.bone.2016.03.017

M3 - Review article

C2 - 27049042

AN - SCOPUS:84962633686

SN - 8756-3282

VL - 87

SP - 57

EP - 70

JO - Bone

JF - Bone

ER -

Bone loss in chronic kidney disease: Quantity or quality?

摘要

ASJC Scopus subject areas

UN SDG

存取文件

其它文件與鏈接

指紋

引用此