Bone loss in chronic kidney disease: Quantity or quality?

Cai Mei Zheng; Jin Quan Zheng; Chia Chao Wu; Chien Lin Lu; Jia Fwu Shyu; Hsu Yung-Ho; Mei Yi Wu; I. Jen Chiu; Yuan Hung Wang; Yuh Feng Lin; Kuo Cheng Lu

doi:10.1016/j.bone.2016.03.017

Bone loss in chronic kidney disease: Quantity or quality?

Cai Mei Zheng, Jin Quan Zheng, Chia Chao Wu, Chien Lin Lu, Jia Fwu Shyu, Hsu Yung-Ho, Mei Yi Wu, I. Jen Chiu, Yuan Hung Wang, Yuh Feng Lin, Kuo Cheng Lu

研究成果: 雜誌貢獻 › 回顧型文獻 › 同行評審

29 引文斯高帕斯（Scopus）

摘要

Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.

原文	英語
頁（從 - 到）	57-70
頁數	14
期刊	Bone
卷	87
DOIs	https://doi.org/10.1016/j.bone.2016.03.017
出版狀態	已發佈 - 6月 1 2016

ASJC Scopus subject areas

內分泌學、糖尿病和代謝
組織學
生理學

UN SDG

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10.1016/j.bone.2016.03.017

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title = "Bone loss in chronic kidney disease: Quantity or quality?",

abstract = "Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.",

keywords = "Bone quantity and bone quality losses, Bone remodeling, Chronic kidney disease-mineral bone disorder (CKD-MBD), Vitamin D therapy",

author = "Zheng, {Cai Mei} and Zheng, {Jin Quan} and Wu, {Chia Chao} and Lu, {Chien Lin} and Shyu, {Jia Fwu} and Hsu Yung-Ho and Wu, {Mei Yi} and Chiu, {I. Jen} and Wang, {Yuan Hung} and Lin, {Yuh Feng} and Lu, {Kuo Cheng}",

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T2 - Quantity or quality?

AU - Zheng, Cai Mei

AU - Zheng, Jin Quan

AU - Wu, Chia Chao

AU - Lu, Chien Lin

AU - Shyu, Jia Fwu

AU - Yung-Ho, Hsu

AU - Wu, Mei Yi

AU - Chiu, I. Jen

AU - Wang, Yuan Hung

AU - Lin, Yuh Feng

AU - Lu, Kuo Cheng

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.

AB - Chronic kidney disease (CKD) patients experience bone loss and fracture because of a specific CKD-related systemic disorder known as CKD-mineral bone disorder (CKD-MBD). The bone turnover, mineralization, and volume (TMV) system describes the morphological bone lesions in renal osteodystrophy related to CKD-MBD. Bone turnover and bone volume are defined as high, normal, or low, and bone mineralization is classified as normal or abnormal. All types of bone histology related to TMV are responsible for both bone quantity and bone quality losses in CKD patients. This review focuses on current bone quantity and bone quality losses in CKD patients and finally discusses potential therapeutic measures.

KW - Bone quantity and bone quality losses

KW - Bone remodeling

KW - Chronic kidney disease-mineral bone disorder (CKD-MBD)

KW - Vitamin D therapy

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DO - 10.1016/j.bone.2016.03.017

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SN - 8756-3282

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JO - Bone

JF - Bone

ER -

Bone loss in chronic kidney disease: Quantity or quality?

摘要

ASJC Scopus subject areas

UN SDG

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