Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Pharmacology, Toxicology and Pharmaceutical Science

• Antitumor Activity 100%
• Colorectal Cancer 100%
• Histone Deacetylase 6 100%
• Pharmacokinetics 50%
• Histone Deacetylase 1 50%
• Malignant Neoplasm 50%
• Histone Deacetylase Inhibitor 50%
• Tumor Growth 50%
• Histone Deacetylase 2 50%
• Antiproliferative Activity 50%
• Vorinostat 50%
• Hydroxamic Acid 50%
• Sulfonyl 50%
• Bioavailability 50%
• IC50 50%