Associations of allergic diseases with indoor and outdoor living environments in preschool children in the Taipei Metropolis

Hsing Jasmine Chao, Ya Wen Yang, Ssu Yin Chen, Ming Lun Zou, Yi Hua Chen, Ling Chu Chien

研究成果: 書貢獻/報告類型會議貢獻

摘要

Various environmental factors are associated with the development and exacerbation of allergic diseases. However, few studies evaluated multiple exposures simultaneously. We conducted a study to assess multiple environmental exposures and their effects on allergic diseases in preschool children in the Taipei Metropolis. We evaluated children's residential environmental exposures and their allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis. According to the preliminary analysis, doctor-diagnosed asthma was positively associated with total airborne fungal spores in the living room, the number of gas stations surrounding the home, and outdoor formaldehyde. Allergic rhinitis showed a significant positive association with outdoor ozone and living room temperature. Atopic dermatitis was significantly and positively correlated with dustborne ascospores in the child's bed and the presence of gas stations near the home. Our findings suggest that residential environments are closely associated with children’s allergic diseases.

The prevalence of children's allergic diseases remains high worldwide, especially in developed countries in Asia. Various environmental factors are associated with the development and exacerbation of allergic diseases. However, few studies evaluated multiple exposures simultaneously, thus lacking a comprehensive evaluation of their impacts on allergic diseases. We conducted a study to assess multiple environmental exposures and their effects on allergic diseases in preschool children in the Taipei Metropolis. We recruited children under six years old in the Taipei Metropolitan area starting in March 2017. We evaluated children's residential environmental exposures and their allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis. The information on children's social demographic data, health history, and home environmental characteristics were collected using a structured questionnaire. Indoor and outdoor air pollutants (e.g., particulates, formaldehyde, and ozone) and environmental microbiome (e.g., microbiota and allergens) were measured in children's bedrooms, living rooms, and outdoor/balconies. Land use types near children's homes were evaluated using buffer analysis in the Geographic Information System. According to the preliminary analysis, doctor-diagnosed asthma was positively associated with total airborne fungal spores in the living room, the number of gas stations surrounding the home, and outdoor formaldehyde. Doctor-diagnosed allergic rhinitis showed a significant positive association with outdoor ozone and living room temperature. Doctor-diagnosed atopic dermatitis was significantly and positively correlated with dustborne ascospores in the child's bed and the presence of gas stations near the home. In addition, the abundance of Lachnospiraceae and Pleosporales in the environment was significantly higher in children with allergic rhinitis. The abundance of Gordonia and Diatrypella was significantly higher in children with atopic dermatitis. Our findings suggest that residential environments are closely associated with children’s allergic diseases. Proper home maintenance and urban planning are crucial to avoid children’s exposure to pollutants and promote their health.
原文英語
主出版物標題18th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2024 - Conference Program and Proceedings
發行者International Society of Indoor Air Quality and Climate
ISBN(電子)9798331306816
出版狀態已發佈 - 2024
事件18th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2024 - Honolulu, 美國
持續時間: 7月 7 20247月 11 2024

出版系列

名字18th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2024 - Conference Program and Proceedings

會議

會議18th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2024
國家/地區美國
城市Honolulu
期間7/7/247/11/24

ASJC Scopus subject areas

  • 污染

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