Association between underlying health conditions and long COVID among non-hospitalized and hospitalized individuals as modified by health literacy: A multi-center study

Han T Vo, Thang V Dao, Tinh X Do, Binh N Do, Tan T Nguyen, Khue M Pham, Vinh H Vu, Linh V Pham, Lien T H Nguyen, Lan T H Le, Hoang C Nguyen, Tuan V Tran, Trung H Nguyen, Anh T Nguyen, Hoan V Nguyen, Phuoc B Nguyen, Thu T M Pham, Tien D Dao, Thuy T Le, Thao T P NguyenCuong Q Tran, Kien T Nguyen, Tuyen V Duong

研究成果: 雜誌貢獻文章同行評審

摘要

Objectives: We investigated the effect modification of health literacy (HL) in ameliorating the negative impact of underlying health conditions (UHC) on long COVID among non-hospitalized and hospitalized survivors.

Study design: An online cross-sectional study was conducted in Vietnam from December 2021 to October 2022.

Methods: A sample of 4507 participants recruited from 18 hospitals and health centers were those aged 18 or older, had contracted COVID-19 for at least 28 days, and were not in the acute phase of reinfection. Participants reported their long COVID symptoms, UHC, health literacy, socio-demographics, clinical parameters, the COVID-19 impact battery disability scale, and health-related behaviors. The logistic regression models were used to examine the associations and interactions.

Results: Underlying health conditions were associated with a higher likelihood of long COVID in non-hospitalized participants (adjusted odds ratio, aOR = 2.10 [1.61, 2.61]; p < 0.001), and hospitalized ones (aOR = 2.26 [1.87, 2.73]; p < 0.001). In non-hospitalized participants, higher HL scores were significantly linked to a reduced likelihood of experiencing long COVID (aOR = 0.96 [0.95, 0.97]; p < 0.001). Furthermore, HL moderated the adverse effect of underlying health conditions (UHC) on long COVID in this group (aOR = 0.97 [0.94-0.99]; p = 0.042). In hospitalized participants, although higher HL scores were also associated with a lower risk of long COVID (aOR = 0.99 [0.98-0.99]; p = 0.036), HL did not significantly mitigate the negative impact of UHC on long COVID (aOR = 1.01 [0.99-1.03]; p = 0.332).

Conclusions: In non-hospitalized individuals, high health literacy ameliorated the negative impact of UHC on long COVID. Such effects of health literacy were not observed in hospitalized COVID-19 survivors.
原文英語
頁(從 - 到)87-93
頁數7
期刊Public Health
239
DOIs
出版狀態打印前電子出版 - 1月 10 2025

Keywords

  • COVID-19 survivors
  • Health literacy
  • Hospitalized
  • Long COVID
  • Underlying health conditions
  • Vietnam

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