TY - JOUR
T1 - Association between ischemic stroke and iron-deficiency anemia
T2 - A population-based study
AU - Chang, Yen Liang
AU - Hung, Shih Han
AU - Ling, Wells
AU - Lin, Herng Ching
AU - Li, Hsien-Chang
AU - Chung, Shiu Dong
PY - 2013/12/9
Y1 - 2013/12/9
N2 - Background: Very little is known about the relationship between non-sickle cell anemia and stroke. The purpose of this study is to evaluate the association of iron-deficiency anemia (IDA) with stroke based on a nationwide coverage database in Taiwan. Methods: The case-control study subjects were obtained from the Taiwanese Longitudinal Health Insurance Database 2000. We included 51,093 subjects with stroke as cases and randomly selected 153,279 controls (3 controls per case) in this study. Separate conditional logistic regression analyses were used to calculate the odds ratio (OR) for having been previously diagnosed with IDA between cases and controls. We further analyzed the association between stroke and IDA by stroke subtype. Results: Results showed that 3,685 study subjects (1.81%) had been diagnosed with IDA prior to the index date; of those subjects, 1,268 (2.48%) were cases and 2,417 (1.58%) were controls (p
AB - Background: Very little is known about the relationship between non-sickle cell anemia and stroke. The purpose of this study is to evaluate the association of iron-deficiency anemia (IDA) with stroke based on a nationwide coverage database in Taiwan. Methods: The case-control study subjects were obtained from the Taiwanese Longitudinal Health Insurance Database 2000. We included 51,093 subjects with stroke as cases and randomly selected 153,279 controls (3 controls per case) in this study. Separate conditional logistic regression analyses were used to calculate the odds ratio (OR) for having been previously diagnosed with IDA between cases and controls. We further analyzed the association between stroke and IDA by stroke subtype. Results: Results showed that 3,685 study subjects (1.81%) had been diagnosed with IDA prior to the index date; of those subjects, 1,268 (2.48%) were cases and 2,417 (1.58%) were controls (p
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U2 - 10.1371/journal.pone.0082952
DO - 10.1371/journal.pone.0082952
M3 - Article
C2 - 24349404
AN - SCOPUS:84891922050
SN - 1932-6203
VL - 8
JO - PLoS ONE
JF - PLoS ONE
IS - 12
M1 - e82952
ER -