摘要
The metabolism of inorganic arsenic takes place through a series of reactions, including reduction and oxidative methylation reactions. Biomethylation is considered a major detoxification pathway for inorganic arsenic. However, interspecies differences exist according to the efficiency with which inorganic arsenic is metabolized and excreted in urine. Intermediate trivalent methylated arsenic species are more cytotoxic and genotoxic than inorganic compounds. The arsenic methylation profile is influenced by demographic characteristics, lifestyle, diet and genetic susceptibility. Inefficient methylation is related to the risk of cancer and noncancer disease.
| 原文 | 英語 |
|---|---|
| 主出版物標題 | Health Hazards of Arsenic Poisoning Environmental |
| 主出版物子標題 | From Epidemic to Pandemic |
| 發行者 | World Scientific Publishing Co. |
| 頁面 | 193-212 |
| 頁數 | 20 |
| ISBN（電子） | 9789814291828 |
| ISBN（列印） | 9814291811, 9789814291811 |
| DOIs | |
| 出版狀態 | 已發佈 - 1月 1 2011 |
ASJC Scopus subject areas
- 一般環境科學
- 一般醫學
UN SDG
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