Areca nut may kill cells in a different way

Mei Huei Lin, Shyun Yeu Liu, Young Chau Liu

研究成果: 書貢獻/報告類型章節


Areca nut (AN, Areca catechu L.) is a popular but carcinogenic chewing material used by approximately 200-600 million people worldwide. In the past few decades, AN has been discovered to possess genotoxic, cytostatic, and cytotoxic effects on cells. Some ingredients of AN, such as AN extract (ANE), arecoline, hydroxychavicol, and oligomeric procyanidins were demonstrated to stimulate apoptotic and/or growth arresting phenotypes in treated cells. However, our recent studies showed that ANE predominantly induces the autophagic responses, albeit the simultaneous initiation of apoptotic pathway. This finding may renew the knowledge about the cytotoxic effects of AN on oral cells in physiological conditions.
主出版物標題Nuts: Properties, Consumption and Nutrition
發行者Nova Science Publishers Inc
出版狀態已發佈 - 2011

ASJC Scopus subject areas

  • 農業與生物科學 (全部)


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