Are emotions associated with activity during rest or interoception? An exploratory fMRI study in healthy subjects

Christine Wiebking, Moritz de Greck, Niall W. Duncan, Alexander Heinzel, Claus Tempelmann, Georg Northoff

研究成果: 雜誌貢獻文章同行評審

45 引文 斯高帕斯(Scopus)

摘要

Imaging studies investigating the default-mode network (DMN) of the brain revealed the phenomenon of elevated neural responses during periods of rest. This effect has been shown to be abnormally elevated in regions of the DMN concerning mood disorders like major depressive disorder (MDD). Since these disorders are accompanied by impaired emotional functioning, this leads to the suggestion of an association between activity during rest conditions and emotions, which remains to be demonstrated in a healthy and clinical population. Controlling for interoceptive processing, a process often closely connected to emotional functioning, we here demonstrate in an fMRI study of 30 healthy subjects the connection between activity during rest conditions in regions of the DMN and emotions in a psychologically, regionally, and stimulus specific way. Our findings provide further insight into the psychological functions underlying rest activity. Our findings in healthy subjects may also have future implications for a better understanding of mood disorders.
原文英語
頁(從 - 到)87-92
頁數6
期刊Neuroscience Letters
491
發行號1
DOIs
出版狀態已發佈 - 3月 10 2011
對外發佈

ASJC Scopus subject areas

  • 一般神經科學

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