Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

Li Ming Yang; Shwu Jiuan Lin; Lie Chwen Lin; Yao Haur Kuo

Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

Li Ming Yang, Shwu Jiuan Lin, Lie Chwen Lin, Yao Haur Kuo

研究成果: 雜誌貢獻 › 文章 › 同行評審

摘要

Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.

原文	英語
頁（從 - 到）	219-225
頁數	7
期刊	Chinese Pharmaceutical Journal
卷	51
發行號	3
出版狀態	已發佈 - 6月 1999

ASJC Scopus subject areas

生物工程
藥學科學

UN SDG

此研究成果有助於以下永續發展目標

其它文件與鏈接

Link to publication in Scopus

引用此

@article{19b1c09836454617bf1413ff0fe6b66a,

title = "Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine",

abstract = "Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.",

keywords = "Antitumor, Evodia rutaecarpa, Quinazolinocarboline alkaloid, Rutaecarpine",

author = "Yang, {Li Ming} and Lin, {Shwu Jiuan} and Lin, {Lie Chwen} and Kuo, {Yao Haur}",

year = "1999",

month = jun,

language = "English",

volume = "51",

pages = "219--225",

journal = "Chinese Pharmaceutical Journal",

issn = "1016-1015",

publisher = "臺灣藥學會",

number = "3",

}

TY - JOUR

T1 - Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

AU - Yang, Li Ming

AU - Lin, Shwu Jiuan

AU - Lin, Lie Chwen

AU - Kuo, Yao Haur

PY - 1999/6

Y1 - 1999/6

N2 - Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.

AB - Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.

KW - Antitumor

KW - Evodia rutaecarpa

KW - Quinazolinocarboline alkaloid

KW - Rutaecarpine

UR - http://www.scopus.com/inward/record.url?scp=0032768680&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032768680&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0032768680

SN - 1016-1015

VL - 51

SP - 219

EP - 225

JO - Chinese Pharmaceutical Journal

JF - Chinese Pharmaceutical Journal

IS - 3

ER -

Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

摘要

ASJC Scopus subject areas

UN SDG

其它文件與鏈接

指紋

引用此