摘要
Bacterial infections have caused serious threats to public health due to the antimicrobial resistance in bacteria. Recently, gold nanoclusters (AuNCs) have been extensively investigated for biomedical applications because of their superior structural and optical properties. Great efforts have demonstrated that AuNCs conjugated with various surface ligands are promising antimicrobial agents owing to their high biocompatibility, polyvalent effect, easy modification and photothermal stability. In this review, we have highlighted the recent achievements for the utilizations of AuNCs as the antimicrobial agents. We have classified the antimicrobial AuNCs by their surface ligands including small molecules (< 900 Daltons) and macromolecules (> 900 Daltons). Moreover, the antimicrobial activities and mechanisms of AuNCs have been introduced into two main categories of small molecules and macromolecules, respectively. In accordance with the advancements of antimicrobial AuNCs, we further provided conclusions of current challenges and recommendations of future perspectives of antimicrobial AuNCs for fundamental researches and clinical applications.
原文 | 英語 |
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文章編號 | 2924 |
期刊 | International Journal of Molecular Sciences |
卷 | 20 |
發行號 | 12 |
DOIs | |
出版狀態 | 已發佈 - 6月 14 2019 |
ASJC Scopus subject areas
- 催化
- 分子生物學
- 光譜
- 電腦科學應用
- 物理與理論化學
- 有機化學
- 無機化學