Anti-inflammatory cembrane-based diterpenoids isolated from the octocoral Sinularia querciformis

Te An Kung, Lo Yun Chen, Chia Ying Li, Bo Rong Peng, Tsong Long Hwang, Ping Jyun Sung, Kuei Hung Lai, Hsu Ming Chung

研究成果: 雜誌貢獻文章同行評審


The exploration of Sinularia querciformis cembranoids afforded two new compounds, querciformolide G (1) and H (2), along with three known ones, sinulaparvalide (3), sinulariolone acetate (4), and 3,4:8,11-bisepoxy-7-hydroxycembra-15(17)-en-1,12-olide (5). The structural elucidation of these compounds was achieved by extensive spectroscopic (IR, ESIMS, 1D and 2D NMR data) analysis and by comparison with those previously reported in the literature. Compounds 1–5 were evaluated for their anti-inflammatory activity. Among all, compound 1 displayed significant inhibitory effects on the elastase release in activated human neutrophils.
頁(從 - 到)12-16
期刊Phytochemistry Letters
出版狀態已發佈 - 6月 2023

ASJC Scopus subject areas

  • 生物技術
  • 生物化學
  • 農學與作物科學
  • 植物科學


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