Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy

H. S. Liu; H. W. Chung; C. J. Juan; S. Y. Tsai; C. Y. Wang; C. C. Chan; G. S. Huang; M. C. Chou; C. S. Lee; C. W. Ko; N. Y. Cho; Cheng Yu Chen

doi:10.3174/ajnr.A1131

Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy

H. S. Liu, H. W. Chung, C. J. Juan, S. Y. Tsai, C. Y. Wang, C. C. Chan, G. S. Huang, M. C. Chou, C. S. Lee, C. W. Ko, N. Y. Cho, Cheng Yu Chen

研究成果: 雜誌貢獻 › 文章 › 同行評審

3 引文斯高帕斯（Scopus）

摘要

The signal-intensity loss from anomalous J-modulation effects due to chemical-shift displacement was investigated on amino acid groups (alanine, valine, leucine, and isoleucine) at 3T by using point-resolved 1H spectroscopy in patients with brain abscess and phantom experiments. With a larger chemical shift between methyl and methine resonances, alanine shows a greater effect of signal-intensity cancellation compared with other amino acids around 0.9 ppm, resulting in noninverted doublets at a TE of 144 ms.

原文	英語
頁（從 - 到）	1644-1648
頁數	5
期刊	American Journal of Neuroradiology
卷	29
發行號	9
DOIs	https://doi.org/10.3174/ajnr.A1131
出版狀態	已發佈 - 10月 2008
對外發佈	是

ASJC Scopus subject areas

神經病學（臨床）
放射學、核子醫學和影像學

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10.3174/ajnr.A1131

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title = "Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy",

abstract = "The signal-intensity loss from anomalous J-modulation effects due to chemical-shift displacement was investigated on amino acid groups (alanine, valine, leucine, and isoleucine) at 3T by using point-resolved 1H spectroscopy in patients with brain abscess and phantom experiments. With a larger chemical shift between methyl and methine resonances, alanine shows a greater effect of signal-intensity cancellation compared with other amino acids around 0.9 ppm, resulting in noninverted doublets at a TE of 144 ms.",

author = "Liu, {H. S.} and Chung, {H. W.} and Juan, {C. J.} and Tsai, {S. Y.} and Wang, {C. Y.} and Chan, {C. C.} and Huang, {G. S.} and Chou, {M. C.} and Lee, {C. S.} and Ko, {C. W.} and Cho, {N. Y.} and Chen, {Cheng Yu}",

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AU - Liu, H. S.

AU - Chung, H. W.

AU - Juan, C. J.

AU - Tsai, S. Y.

AU - Wang, C. Y.

AU - Chan, C. C.

AU - Huang, G. S.

AU - Chou, M. C.

AU - Lee, C. S.

AU - Ko, C. W.

AU - Cho, N. Y.

AU - Chen, Cheng Yu

PY - 2008/10

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AB - The signal-intensity loss from anomalous J-modulation effects due to chemical-shift displacement was investigated on amino acid groups (alanine, valine, leucine, and isoleucine) at 3T by using point-resolved 1H spectroscopy in patients with brain abscess and phantom experiments. With a larger chemical shift between methyl and methine resonances, alanine shows a greater effect of signal-intensity cancellation compared with other amino acids around 0.9 ppm, resulting in noninverted doublets at a TE of 144 ms.

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Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopy

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