@inproceedings{c23f419154854ca59a5aaa09c5404629,
title = "An integrated system of RBCs sorting and Brownian motion bio-sensing technique",
abstract = "A clinical sorting chip integrated with new protein sensing technique has been developed in this work. Antibody-coated nanobeads reacted with antigen was separated from blood plasma based on dielectrophoresis (DEP) forces. MEMS fabrication process was used to produce the bio-chip and only two photo masks were required in the experiment. By using oxygen-plasma direct bonding method, the assembly of an electrode chip and the microchannels will form a set of RBCs and nanobeads separating chip. The original concentration of antigen can be rapidly estimated by nanobeads' Brownian motion measurement in varies of the viscous solutions. During the antibody-antigen reacting, the mean value of the beads diameter increased so that the Brownian velocity decreased with increasing time. The Brownian motion of nanobeads was observed and measured by micro-particle tracking velocimetry (μ-PTV).",
keywords = "Biosensing, Brownian motion, Dielectrophoresis (DEP), Micro-particle tracking velocimetry (μ-PTV)",
author = "Fan, {Yu Jui} and Lee, {Ching Jiun} and Hsu, {Jen Hao} and Liu, {Yi Hsing} and Yeh, {Szu I.} and Sheen, {Horn Jiunn} and Shiming Lin and Tsai, {Jing Fa}",
year = "2010",
doi = "10.1109/NEMS.2010.5592441",
language = "English",
isbn = "9781424465439",
series = "2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010",
pages = "487--491",
booktitle = "2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010",
note = "5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010 ; Conference date: 20-01-2010 Through 23-01-2010",
}