An integrated microfluidic chip for the study of metastasis and angiogenesis

Yong Yu Hsu; Kuo Wei Chang; Tse Shao Chen; Kang Yun Lee; Chen Shien Liu

doi:10.1109/NEMS.2014.6908842

An integrated microfluidic chip for the study of metastasis and angiogenesis

Yong Yu Hsu, Kuo Wei Chang, Tse Shao Chen, Kang Yun Lee, Chen Shien Liu

研究成果: 書貢獻/報告類型 › 會議貢獻

2 引文斯高帕斯（Scopus）

摘要

Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

原文	英語
主出版物標題	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
發行者	Institute of Electrical and Electronics Engineers Inc.
頁面	426-429
頁數	4
ISBN（列印）	9781479947270
DOIs	https://doi.org/10.1109/NEMS.2014.6908842
出版狀態	已發佈 - 9月 23 2014
事件	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 - Waikiki Beach, 美国持續時間: 4月 13 2014 → 4月 16 2014

其他

其他	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
國家/地區	美国
城市	Waikiki Beach
期間	4/13/14 → 4/16/14

ASJC Scopus subject areas

控制與系統工程
電氣與電子工程

UN SDG

此研究成果有助於以下永續發展目標

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10.1109/NEMS.2014.6908842

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Hsu, Y. Y., Chang, K. W., Chen, T. S., Lee, K. Y., & Liu, C. S. (2014). An integrated microfluidic chip for the study of metastasis and angiogenesis. 於 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 (頁 426-429). Article 6908842 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEMS.2014.6908842

Hsu, YY, Chang, KW, Chen, TS, Lee, KY & Liu, CS 2014, An integrated microfluidic chip for the study of metastasis and angiogenesis. 於 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014., 6908842, Institute of Electrical and Electronics Engineers Inc., 頁 426-429, 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014, Waikiki Beach, 美国, 4/13/14. https://doi.org/10.1109/NEMS.2014.6908842

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title = "An integrated microfluidic chip for the study of metastasis and angiogenesis",

abstract = "Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.",

keywords = "angiogenesis, extracellular matrix (ECM), Lung cancer, pattern, vascular endothelial cell",

author = "Hsu, {Yong Yu} and Chang, {Kuo Wei} and Chen, {Tse Shao} and Lee, {Kang Yun} and Liu, {Chen Shien}",

year = "2014",

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doi = "10.1109/NEMS.2014.6908842",

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booktitle = "9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014",

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T1 - An integrated microfluidic chip for the study of metastasis and angiogenesis

AU - Hsu, Yong Yu

AU - Chang, Kuo Wei

AU - Chen, Tse Shao

AU - Lee, Kang Yun

AU - Liu, Chen Shien

PY - 2014/9/23

Y1 - 2014/9/23

N2 - Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

AB - Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

KW - angiogenesis

KW - extracellular matrix (ECM)

KW - Lung cancer

KW - pattern

KW - vascular endothelial cell

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DO - 10.1109/NEMS.2014.6908842

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AN - SCOPUS:84908619545

SN - 9781479947270

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EP - 429

BT - 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014

Y2 - 13 April 2014 through 16 April 2014

ER -

An integrated microfluidic chip for the study of metastasis and angiogenesis

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ASJC Scopus subject areas

UN SDG

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