An efficient S-NO-polysilsesquioxane nano-platform for the co-delivery of nitric oxide and an anticancer drug

Meng Ren Wang; Shih Jiuan Chiu; Hung Chang Chou; Teh Min Hu

doi:10.1039/c5cc06087g

An efficient S-NO-polysilsesquioxane nano-platform for the co-delivery of nitric oxide and an anticancer drug

Meng Ren Wang, Shih Jiuan Chiu, Hung Chang Chou, Teh Min Hu

研究成果: 雜誌貢獻 › 文章 › 同行評審

25 引文斯高帕斯（Scopus）

摘要

Codelivery of nitric oxide (NO) and drugs based on a single nanocarrier is a promising therapeutic strategy. Here, we report a one-step nanoprecipitation method to generate nanoparticles that possess simultaneous NO-donating and doxorubicin releasing properties. S-Nitroso polysilsesquioxane acts like an avid "drug sponge" that attracts drug molecules into nanospheres.

原文	英語
頁（從 - 到）	15649-15652
頁數	4
期刊	Chemical Communications
卷	51
發行號	86
DOIs	https://doi.org/10.1039/c5cc06087g
出版狀態	已發佈 - 9月 1 2015

ASJC Scopus subject areas

電子、光磁材料
一般化學
陶瓷和複合材料
金屬和合金
材料化學
表面、塗料和薄膜
催化

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10.1039/c5cc06087g

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N1 - Publisher Copyright: © The Royal Society of Chemistry.

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An efficient S-NO-polysilsesquioxane nano-platform for the co-delivery of nitric oxide and an anticancer drug

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