摘要
Background: The study was designed to investigate the clinical usefulness of Amplified Mycobacterium Tuberculosis Direct (AMTD) tests for diagnosing TB pleurisy.
Methods: One hundred and fifty-two patients for whom the exclusion of tuberculous pleural effusion was necessary were retrospectively analyzed.
Results: The sensitivity of AMTD in diagnosing pleural TB was 36.4% (20 of 55). Combining sputum and pleural effusion AFB smear, pleural biopsy, and AMTD test of pleural effusion increased sensitivity to 82.5% (33/40). There were significantly higher percentages of neutrophils in the pleural effusion in the positive than in the negative AMTD group (38.0 ± 6.7% vs. 11.1 ± 3.7%, p18 days (70% vs. 31.4%; OR 5.09; 95% CI 1.54-16.79; p = 0.011).
Conclusions: Combining AMTD tests with conventional diagnostic methods offer good sensitivity for pleural TB diagnosis. Patients in the early course of the disease are better candidates for AMTD tests.
Methods: One hundred and fifty-two patients for whom the exclusion of tuberculous pleural effusion was necessary were retrospectively analyzed.
Results: The sensitivity of AMTD in diagnosing pleural TB was 36.4% (20 of 55). Combining sputum and pleural effusion AFB smear, pleural biopsy, and AMTD test of pleural effusion increased sensitivity to 82.5% (33/40). There were significantly higher percentages of neutrophils in the pleural effusion in the positive than in the negative AMTD group (38.0 ± 6.7% vs. 11.1 ± 3.7%, p18 days (70% vs. 31.4%; OR 5.09; 95% CI 1.54-16.79; p = 0.011).
Conclusions: Combining AMTD tests with conventional diagnostic methods offer good sensitivity for pleural TB diagnosis. Patients in the early course of the disease are better candidates for AMTD tests.
| 原文 | 英語 |
|---|---|
| 文章編號 | e44842 |
| 期刊 | PLoS ONE |
| 卷 | 7 |
| 發行號 | 9 |
| DOIs | |
| 出版狀態 | 已發佈 - 9月 10 2012 |
| 對外發佈 | 是 |
ASJC Scopus subject areas
- 多學科
UN SDG
此研究成果有助於以下永續發展目標
