TY - JOUR
T1 - American ginseng supplementation attenuates creatine kinase level induced by submaximal exercise in human beings
AU - Hsu, Cheng Chen
AU - Ho, Min Chen
AU - Lin, Li Chin
AU - Su, Borcherng
AU - Hsu, Mei Chich
PY - 2005/9/14
Y1 - 2005/9/14
N2 - Aim: To investigate whether American ginseng (AG, Panax quinquefolium) supplementation was able to improve endurance exercise performance. Methods: Thirteen physically active male college students were divided into two groups (AG or placebo) and received supplementation for 4 wk, before the exhaustive running exercise. Treadmill speed was increased to a pace equivalent to 80% VO2max of the subject. A 4-wk washout period followed before the subjects crossed over and received the alternate supplement for the next 4 wk. They then completed a second exhaustive running exercise. The physiological variables that were examined included time to exhaustion and oxygen pulse. Moreover, the plasma creatine kinase (CK) and lactate were measured prior to the exercise, at 15 and 30 min during exercise, immediately after exercise, and 20, 40, 60, and 120 min after exercise. Results: The major finding of this investigation was that the production plasma CK during the exercise significantly decreased for group AG than for group P. Secondary physiological finding was that 80% VO2max running was not improved over a 4-wk AG supplementation regimen. Conclusion: Supplementation with AG for 4 wk prior to an exhaustive aerobic treadmill running reduced the leakage of CK during exercise, but did not enhance aerobic work capacity. The reduction of plasma CK may be due to the fact that AG is effective for the decrease of skeletal muscle cell membrane damage, induced by exercise during the high-intensity treadmill run.
AB - Aim: To investigate whether American ginseng (AG, Panax quinquefolium) supplementation was able to improve endurance exercise performance. Methods: Thirteen physically active male college students were divided into two groups (AG or placebo) and received supplementation for 4 wk, before the exhaustive running exercise. Treadmill speed was increased to a pace equivalent to 80% VO2max of the subject. A 4-wk washout period followed before the subjects crossed over and received the alternate supplement for the next 4 wk. They then completed a second exhaustive running exercise. The physiological variables that were examined included time to exhaustion and oxygen pulse. Moreover, the plasma creatine kinase (CK) and lactate were measured prior to the exercise, at 15 and 30 min during exercise, immediately after exercise, and 20, 40, 60, and 120 min after exercise. Results: The major finding of this investigation was that the production plasma CK during the exercise significantly decreased for group AG than for group P. Secondary physiological finding was that 80% VO2max running was not improved over a 4-wk AG supplementation regimen. Conclusion: Supplementation with AG for 4 wk prior to an exhaustive aerobic treadmill running reduced the leakage of CK during exercise, but did not enhance aerobic work capacity. The reduction of plasma CK may be due to the fact that AG is effective for the decrease of skeletal muscle cell membrane damage, induced by exercise during the high-intensity treadmill run.
KW - American ginseng
KW - Creatine kinase
KW - Endurance exercise
KW - Panax quinquefolium
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U2 - 10.3748/wjg.v11.i34.5327
DO - 10.3748/wjg.v11.i34.5327
M3 - Article
C2 - 16149140
AN - SCOPUS:26244456602
SN - 1007-9327
VL - 11
SP - 5327
EP - 5331
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
IS - 34
ER -