All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan

B. Y. Hsiao; L. I. Hsu; C. J. Chen; Hung Yi Chiou

All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan

B. Y. Hsiao, L. I. Hsu, C. J. Chen, Hung Yi Chiou

研究成果: 書貢獻/報告類型 › 會議貢獻

摘要

The association of low-to-moderate arsenic exposure with cause-specific mortality has never been reported in Taiwan. This study aimed to elucidate the dose-response relation of mortality from various causes of death with the arsenic concentration in drinking water and cumulative arsenic exposure. A total of 8,088 residents from northeastern Taiwan were followed from 1991 to 2011. Cox regression analysis was used to determine the hazard ratio of cause-specific mortality associated with two indices of arsenic exposure. A total of 3,106 deaths were ascertained during the follow-up period of 120,768 person-years. The multivariate-adjusted hazard ratio (95% confidence interval) was 1.25 (1.04-1.50), 1.32 (0.96-1.81), 2.41 (1.43-4.05), 4.00 (1.17-13.70), 3.58 (0.92-13.93) and 2.31 (1.43-3.75), respectively, for mortality from all-causes, all cancers, lung cancer, urinary cancer, occlusive stroke, and respiratory disease for arsenic level in drinking water ≥500.0 μg/L compared to

原文	英語
主出版物標題	One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment
發行者	CRC Press/Balkema
頁面	580-581
頁數	2
ISBN（列印）	9781138001411
出版狀態	已發佈 - 2014
事件	5th International Congress on Arsenic in the Environment, As 2014 - Buenos Aires, 阿根廷持續時間: 5月 11 2014 → 5月 16 2014

其他

其他	5th International Congress on Arsenic in the Environment, As 2014
國家/地區	阿根廷
城市	Buenos Aires
期間	5/11/14 → 5/16/14

ASJC Scopus subject areas

化學健康與安全

UN SDG

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Hsiao, B. Y., Hsu, L. I., Chen, C. J., & Chiou, H. Y. (2014). All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. 於 One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment (頁 580-581). CRC Press/Balkema.

All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. / Hsiao, B. Y.; Hsu, L. I.; Chen, C. J. 等.
One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, 2014. p. 580-581.

研究成果: 書貢獻/報告類型 › 會議貢獻

Hsiao, BY, Hsu, LI, Chen, CJ & Chiou, HY 2014, All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. 於 One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, 頁 580-581, 5th International Congress on Arsenic in the Environment, As 2014, Buenos Aires, 阿根廷, 5/11/14.

Hsiao BY, Hsu LI, Chen CJ, Chiou HY. All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. 於 One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema. 2014. p. 580-581

Hsiao, B. Y. ; Hsu, L. I. ; Chen, C. J. 等. / All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water : A prospective cohort study in northeastern Taiwan. One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, 2014. 頁 580-581

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AB - The association of low-to-moderate arsenic exposure with cause-specific mortality has never been reported in Taiwan. This study aimed to elucidate the dose-response relation of mortality from various causes of death with the arsenic concentration in drinking water and cumulative arsenic exposure. A total of 8,088 residents from northeastern Taiwan were followed from 1991 to 2011. Cox regression analysis was used to determine the hazard ratio of cause-specific mortality associated with two indices of arsenic exposure. A total of 3,106 deaths were ascertained during the follow-up period of 120,768 person-years. The multivariate-adjusted hazard ratio (95% confidence interval) was 1.25 (1.04-1.50), 1.32 (0.96-1.81), 2.41 (1.43-4.05), 4.00 (1.17-13.70), 3.58 (0.92-13.93) and 2.31 (1.43-3.75), respectively, for mortality from all-causes, all cancers, lung cancer, urinary cancer, occlusive stroke, and respiratory disease for arsenic level in drinking water ≥500.0 μg/L compared to

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All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan

摘要

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ASJC Scopus subject areas

UN SDG

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