Aldehyde dehydrogenase mutation exacerbated high-fat-diet-induced nonalcoholic fatty liver disease with gut microbiota remodeling in male mice

Agriculture & Biology

• aldehyde dehydrogenase 99%
• fatty liver 95%
• high fat diet 82%
• intestinal microorganisms 77%
• mutation 52%
• mice 44%
• acetaldehyde 20%
• metabolic syndrome 16%
• Deferribacteres 11%
• glucose tolerance tests 8%
• liver diseases 7%
• white adipose tissue 7%
• insulin resistance 7%
• sex hormones 7%
• liver 6%
• stroke 6%
• tissue weight 6%
• alanine transaminase 6%
• retina 5%
• Actinobacteria 5%
• homeostasis 5%
• alcohols 4%
• ethanol 4%
• genes 4%
• glucose 3%
• metabolism 3%
• enzymes 2%
• cells 1%

Medicine & Life Sciences

• Aldehyde Dehydrogenase 100%
• Non-alcoholic Fatty Liver Disease 82%
• High Fat Diet 77%
• Gastrointestinal Microbiome 76%
• Mutation 43%
• Acetaldehyde 27%
• mouse ALDH2 protein 14%
• Metabolic Syndrome 12%
• Mitochondrial Aldehyde Dehydrogenase 11%
• Actinobacteria 8%
• White Adipose Tissue 8%
• Gonadal Steroid Hormones 7%
• Liver 7%
• Glucose Tolerance Test 7%
• Alanine Transaminase 6%
• Inbred C57BL Mouse 6%
• Retina 6%
• Ethanol 5%
• Liver Diseases 5%
• Insulin Resistance 5%
• Alcohols 5%
• Homeostasis 5%
• Stroke 4%
• Weights and Measures 4%
• Glucose 4%
• Gene Expression 4%
• Enzymes 3%
• Serum 3%
• Genes 2%

Chemical Compounds

• Mutation 65%
• Acetaldehyde 18%
• Metabolic 9%
• Gonadal Steroid Hormone 8%
• Serum Level 8%
• Clearance 6%
• Insulin Derivative 6%
• Alanine 5%
• Protective 4%
• Pharmacological Metabolism 4%
• Glucose 4%
• Ethanol 3%
• Resistance 3%
• Weight 3%