Alcohol levels in Chinese lactating mothers after consumption of alcoholic diet during postpartum "doing-the-month" ritual

Yeh Chung Chien, Jen-Fang Liu, Ya Jing Huang, Chun-Sen Hsu, Jane C J Chao

研究成果: 雜誌貢獻文章同行評審

28 引文 斯高帕斯(Scopus)


This study examined the effects of exposure to ethanol through cultural practices by lactating mothers. Specifically, the pharmacokinetics of alcohol in Chinese lactating mothers was investigated after they consumed chicken soup flavored with sesame oil and rice wine (CSSR), a typically prescribed diet during the postpartum "doing-the-month" period. Experimental findings were employed to estimate the potential ethanol dose to neonates and determine associated health risks. Twenty-three lactating mothers were examined. Informed consent was obtained from each subject. The target alcohol dosage was 0.3 g/kg. Milk and blood samples were collected at fixed time intervals from each subject following exposure to CSSR, and alcohol levels were determined. Acute health risks to infants were estimated by comparing the potential infant dosage to an established criterion dose. Blood alcohol level peaked at 20 min after exposure to CSSR and decreased almost linearly thereafter. Alcohol in milk reached a plateau roughly at 20-40 min after exposure to CSSR and then decreased. Alcohol pharmacokinetics among subjects varied widely. The coefficients of variation in subject alcohol concentrations were 16.5-46.2% (mean, 30.0%) for blood and 32.8-57.6% (mean, 44.4%) for milk. Mean maximal alcohol concentration in blood (30.2 ± 5.0 mg/dl) was achieved at 23.5 ± 7.6 min and in milk (31.6 ± 10.3 mg/dl) at 31.7 ± 12.7 min. Potential infant doses were 3.0-58.8 mg (mean, 13.4 mg), and the predicted time required for milk alcohol level to return to zero level was 175 min. The acute health risks for infants exposed to alcohol through their mothers' milk under the current exposure scenario are low (hazard index <0.2). Nursing infants at least 3 h after ingesting a diet containing alcohol would further reduce potential health risks.
頁(從 - 到)143-150
出版狀態已發佈 - 11月 2006

ASJC Scopus subject areas

  • 生物化學
  • 醫藥 (全部)
  • 行為神經科學
  • 神經科學 (全部)
  • 毒理學
  • 健康(社會科學)


深入研究「Alcohol levels in Chinese lactating mothers after consumption of alcoholic diet during postpartum "doing-the-month" ritual」主題。共同形成了獨特的指紋。