@article{fcc364b9e0a3402c8f7279a7ad70c9f1,
title = "Aggressive hepatic resection for patients with pyogenic liver abscess and APACHE II score ≥15",
abstract = "Background: Most liver abscesses resolve after antimicrobial therapy or percutaneous tube drainage (PD). The aim of this study was to evaluate the results of hepatic resection (HR) for patients with pyogenic liver abscesses and an Acute Physiology and Chronic Health Evaluation II (APACHE II) score ≥15. Methods: We compared the clinical outcomes of 81 patients with APACHE II scores ≥15 undergoing PD and/or HR. Results: The failure rate (3 of 65) and double-treatment rate (32 of 65) in the PD group were significantly higher than in the HR group (3 of 35 vs 0 of 35; P = .0002). The mortality rate in the PD group was significantly higher than the other 2 groups (14 of 46 vs 2 of 19 and 1 of 16; P = .038). The length of hospital stay was significantly shorter and antibiotic use less in the HR group than in the PD group (P <.05). Conclusions: Aggressive HR for patients with liver abscesses and APACHE II scores ≥15 produced better clinical outcomes. {\textcopyright} 2008 Elsevier Inc. All rights reserved.",
keywords = "APACHE II, Hepatic resection, Pyogenic liver abscess, adult, aged, antibiotic therapy, APACHE, article, female, hospitalization, human, length of stay, liver surgery, major clinical study, male, outcome assessment, priority journal, pyogenic liver abscess, statistical significance, surgical mortality, Aged, Aged, 80 and over, Female, Hepatectomy, Humans, Liver Abscess, Pyogenic, Male, Middle Aged, Treatment Outcome",
author = "Huan-Fa Hsieh and Teng-Wei Chen and Chih-Yung Yu and Ning-Chi Wang and Heng-Cheng Chu and Ming-Liang Shih and Jyh-Cherng Yu and Chung-Bao Hsieh",
note = "被引用次數：16 Export Date: 22 March 2016 CODEN: AJSUA 通訊地址: Hsieh, C.-B.; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan; 電子郵件： albert0920@yahoo.com.tw 參考文獻: Jepsen, P., Vilstrup, H., Schonheyder, H.C., A nationwide study of the incidence and 30-day mortality rate of pyogenic liver abscesses in Denmark, 1977-2002 (2005) Aliment Pharmacol Ther, 21, pp. 1185-1188; Wang, J.H., Liu, Y.C., Lee, S.S.J., Primary liver abscess due to Klebsiella pneumoniae in Taiwan (1998) Clin Infect Dis, 26, pp. 1434-1438; Cheng, H.P., Siu, L.K., Chang, F.Y., Extended-spectrum cephalosporin compared to cefazolin for treatment of Klebsiella pneumoniae-caused liver abscess (2003) Antimicrob Agent Chemother, 47, pp. 2088-2092; Chu, K.M., Fan, S.T., Lai, E.C.S., Pyogenic liver abscess: an audit of experience over the past decade (1996) Arch Surg, 131, pp. 148-152; Chou, F.F., Sheen-Chen, S.M., Chen, Y.S., Prognostic factors for pyogenic abscess of the liver (1994) J Am Coll Surg, 179, pp. 727-732; Kandel, G., Marcon, N.E., Pyogenic liver abscess: new concepts of an old disease (1984) Am J Gastroenterol, 79, pp. 217-226; Tan, Y.M., Chung, Y.F., Chow, K.H., An appraisal of surgical and percutaneous drainage for pyogenic liver abscesses larger than 5 cm (2005) Ann Surg, 241, pp. 485-490; Huang, C.J., Pitt, H.A., Lipsett, P.A., Pyogenic hepatic abscess: change trends over 42 years (1996) Ann Surg, 223, pp. 600-609; Chou, F.F., Sheen-Chen, S.M., Chen, Y.S., Single and multiple pyogenic liver abscesses: clinical course, etiology and results of treatment (1997) World J Surg, 21, pp. 384-389; Levison, M.A., Zeigler, D., Michigan, D., Correlation of APACHE II score, drainage technique and outcome in postoperative intra-abdominal abscess (1991) Surg Gynecol Obset, 172, pp. 89-94; Knaus, W.A., Draper, E.A., Wagner, D.P., APACHE II: a severity of disease classification (1985) Crit Care Med, 13, pp. 818-829; Hsieh, C.B., Tzao, C., Yu, C.Y., APACHE II score predicts hospital mortality in patients with pyogenic liver abscess (2006) Dig Liver Dis, 38, pp. 498-502; Dindo, D., Demartines, N., Clavien, P.A., Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey (2004) Ann Surg, 240, pp. 205-213; Ochsner, A., DeBakey, M., Murray, S., Pyogenic abscess of the liver: II. An analysis of forty-seven cases with review of the literature (1938) Am J Surg, 40, pp. 292-319; Pitt, H.A., Zuidema, G.D., Factors influencing mortality in the treatment of pyogenic hepatic abscess (1975) Surg Gynecol Obstet, 140, pp. 228-234; Balasegaram, M., Management of hepatic abscess (1981) Curr Probl Surg, 18, pp. 282-340; Chang, F.Y., Chou, M.Y., Comparison of pyogenic liver abscesses caused by Klebsiella pneumoniae and non-K. pneumoniae pathogens (1995) J Formos Med Assoc, 94, pp. 232-237; Mischinger, H.J., Hauser, H., Rabl, H., Pyogenic liver abscess: studies of therapy and analysis of risk factors (1994) World J Surg, 18, pp. 852-858; Klatchko, B.A., Schwartz, S.I., Diagnostic and therapeutic approaches to pyogenic abscess of the liver (1989) Surg Gynecol Obstet, 168, pp. 332-336; van Sonnenberg, E., Wittich, G.R., Goodacre, B.W., Percutaneous abscess drainage: update (2001) World J Surg, 25, pp. 362-372; Imamura, H., Seyama, Y., Kokudo, N., One thousand fifty-six hepatectomies without mortality in 8 years (2003) Arch Surg, 138, pp. 1198-1206; Fan, S.T., Lo, C.M., Liu, C.L., Hepatectomy for hepatocellular carcinoma: toward zero hospital deaths (1999) Ann Surg, 229, pp. 322-330; Herman, P., Pugliese, V., Montagnini, A.L., Pyogenic liver abscess: the role of surgical treatment (1997) Int Surg, 82, pp. 98-101; Farges, O., Leese, T., Bismuth, H., Pyogenic liver abscess: an improvement in prognosis (1988) Br J Surg, 75, pp. 862-865",
year = "2008",
doi = "10.1016/j.amjsurg.2007.09.051",
language = "English",
volume = "196",
pages = "346--350",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "3",
}
