摘要
In wavelength surface plasmon resonance (SPR) biosensor, the manipulation of SPR dispersion relation by Ag/Au bi-metallic film was first time implemented. Due to the enhanced resonant wavelength shift and the sharper SPR slope of using Ag/Au bi-metallic film, the illuminated color of reflection shows one order of magnitude greater contrast than conventional SPR biosensors. Such an Ag/Au bi-metallic film based color SPR biosensor (CSPRB) allows the detail bio-interactions, for example 100. nM streptavidin, to be distinguished by directly observing the color change of reflection through naked eyes rather than the analysis of spectrometer. In addition to the enhanced sensitivity and color contrast, this CSPRB also possesses a great linear detection range up to 0.0254. RIU, which leading to the application of point-of-care tests.
原文 | 英語 |
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頁(從 - 到) | 192-198 |
頁數 | 7 |
期刊 | Biosensors and Bioelectronics |
卷 | 36 |
發行號 | 1 |
DOIs | |
出版狀態 | 已發佈 - 6月 2012 |
ASJC Scopus subject areas
- 生物技術
- 生物物理學
- 生物醫學工程
- 電化學