TY - JOUR
T1 - A systematic review and meta-analysis of randomized control trials
T2 - efficacy of cognitive behavioral therapies for the management of functional and recurrent abdominal pain disorders in children and adolescents
AU - Chen, Jia Yi
AU - Chen, Sheng Ni
AU - Lee, Che Hsiung
AU - Huang, Yu Jui
N1 - Publisher Copyright:
© 2023 Swedish Association for Behaviour Therapy.
PY - 2023
Y1 - 2023
N2 - Cognitive behavioral therapy (CBT) is effective for pain relief in children and adolescents with functional abdominal pain disorders (FAPDs). However, few studies have focused on the FAPDs specifically and the medium-term or long-term results of CBT. In this meta-analysis, we investigated the efficacy of CBT in pediatric FAPDs and unclassified chronic or recurrent abdominal pain (CAP and RAP, respectively). We searched the PubMed, Embase, and Cochrane Library databases for related randomized controlled trials until August 2021. Eventually, 10 trials with 872 participants were included. The methodological quality of the studies was assessed, and data on two primary and four secondary outcomes of interest were extracted. We used the standardized mean difference (SMD) to measure the same outcome, and precisions of effect sizes were reported as 95% confidence intervals (CIs). We found that CBT had significantly positive effects on reducing pain intensity immediately (SMD: −0.54 [CI: −0.9, −0.19], p = 0.003), 3 months after the intervention (SMD: −0.55; [CI: −1.01, −0.1], p = 0.02) and 12 months after the intervention (SMD: −0.32; [CI: −0.56, −0.08], p = 0.008). CBT also reduced the severity of gastrointestinal symptoms, depression, and solicitousness, improved the quality of life and decreased the total social cost. Future studies should consider uniform interventions in the control group and comparing different CBT delivery methods.
AB - Cognitive behavioral therapy (CBT) is effective for pain relief in children and adolescents with functional abdominal pain disorders (FAPDs). However, few studies have focused on the FAPDs specifically and the medium-term or long-term results of CBT. In this meta-analysis, we investigated the efficacy of CBT in pediatric FAPDs and unclassified chronic or recurrent abdominal pain (CAP and RAP, respectively). We searched the PubMed, Embase, and Cochrane Library databases for related randomized controlled trials until August 2021. Eventually, 10 trials with 872 participants were included. The methodological quality of the studies was assessed, and data on two primary and four secondary outcomes of interest were extracted. We used the standardized mean difference (SMD) to measure the same outcome, and precisions of effect sizes were reported as 95% confidence intervals (CIs). We found that CBT had significantly positive effects on reducing pain intensity immediately (SMD: −0.54 [CI: −0.9, −0.19], p = 0.003), 3 months after the intervention (SMD: −0.55; [CI: −1.01, −0.1], p = 0.02) and 12 months after the intervention (SMD: −0.32; [CI: −0.56, −0.08], p = 0.008). CBT also reduced the severity of gastrointestinal symptoms, depression, and solicitousness, improved the quality of life and decreased the total social cost. Future studies should consider uniform interventions in the control group and comparing different CBT delivery methods.
KW - cognitive behavior therapy
KW - Functional abdominal pain
KW - pain intensity
KW - pediatrics
KW - review
KW - social cost
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U2 - 10.1080/16506073.2023.2200562
DO - 10.1080/16506073.2023.2200562
M3 - Review article
C2 - 37102319
AN - SCOPUS:85158146700
SN - 1650-6073
VL - 52
SP - 438
EP - 459
JO - Cognitive Behaviour Therapy
JF - Cognitive Behaviour Therapy
IS - 5
ER -