TY - JOUR
T1 - A case report of Japanese encephalitis focusing on MR findings
AU - Lee, Hsun Hua
AU - Huang, Li Kai
AU - Hu, Chaur Jong
AU - Chen, David Yen Ting
AU - Wu, Dean
PY - 2014
Y1 - 2014
N2 - Japanese encephalitis virus (JEV) infection can manifest with nonspecific febrile illness, aseptic meningitis or encephalitis with or without neurological deficits. JEV typically attacks the thalamus, corpus striatum, brainstem and spinal cord. The laboratory diagnosis of JEV infection involves the detection of anti-JEV antibody IgMs using an enzyme-linked immunosorbent assay (ELISA), which has high sensitivity and specificity. Because of the lack of a specific antiviral therapy, JE is usually managed by symptomatic treatment and supportive care. We report a case of JE in a 34-year-old man. With a clinical presentation similar to herpes simplex virus encephalitis, the patient was finally diagnosed as having JE. The distinction of different viral encephalitides in MR findings is briefly reviewed.
AB - Japanese encephalitis virus (JEV) infection can manifest with nonspecific febrile illness, aseptic meningitis or encephalitis with or without neurological deficits. JEV typically attacks the thalamus, corpus striatum, brainstem and spinal cord. The laboratory diagnosis of JEV infection involves the detection of anti-JEV antibody IgMs using an enzyme-linked immunosorbent assay (ELISA), which has high sensitivity and specificity. Because of the lack of a specific antiviral therapy, JE is usually managed by symptomatic treatment and supportive care. We report a case of JE in a 34-year-old man. With a clinical presentation similar to herpes simplex virus encephalitis, the patient was finally diagnosed as having JE. The distinction of different viral encephalitides in MR findings is briefly reviewed.
KW - Herpes simplex virus
KW - Japanese encephalitis virus
KW - Viral encephalitis
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M3 - Article
C2 - 26082418
AN - SCOPUS:84927136388
SN - 1028-768X
VL - 23
SP - 134
EP - 137
JO - Acta Neurologica Taiwanica
JF - Acta Neurologica Taiwanica
IS - 4
ER -