A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process

Tushar Harishchandra Punde; Wen Hao Wu; Pei Chun Lien; Po Chen Shih; Margaret Dah Tsyr Chang; Kang Yun Lee; Han Pin Kuo; Cheng Hsien Liu

A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process

Tushar Harishchandra Punde, Wen Hao Wu, Pei Chun Lien, Po Chen Shih, Margaret Dah Tsyr Chang, Kang Yun Lee, Han Pin Kuo, Cheng Hsien Liu

研究成果: 書貢獻/報告類型 › 會議貢獻

摘要

We report a 3D biomimetic microsystem which mimics lung microenvironment for monitoring the role of chemokine induced lung inflammation. The extravasation of fibrocytes in response to eosinophil cationic protein (ECP)-stimulated bronchial epithelial cells induced lung inflammation was mimicked on the micro-fluidic chip system for monitoring the microenvironmental changes.

原文	英語
主出版物標題	Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
發行者	Chemical and Biological Microsystems Society
頁面	1021-1023
頁數	3
ISBN（列印）	9780979806452
出版狀態	已發佈 - 2012
對外發佈	是
事件	16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, 日本持續時間: 10月 28 2012 → 11月 1 2012

其他

其他	16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
國家/地區	日本
城市	Okinawa
期間	10/28/12 → 11/1/12

ASJC Scopus subject areas

化學工程（雜項）
生物工程

其它文件與鏈接

引用此

Punde, T. H., Wu, W. H., Lien, P. C., Shih, P. C., Chang, M. D. T., Lee, K. Y., Kuo, H. P., & Liu, C. H. (2012). A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process. 於 Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (頁 1021-1023). Chemical and Biological Microsystems Society.

A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process. / Punde, Tushar Harishchandra; Wu, Wen Hao; Lien, Pei Chun 等.
Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, 2012. p. 1021-1023.

研究成果: 書貢獻/報告類型 › 會議貢獻

Punde, TH, Wu, WH, Lien, PC, Shih, PC, Chang, MDT, Lee, KY , Kuo, HP & Liu, CH 2012, A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process. 於 Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, 頁 1021-1023, 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, Okinawa, 日本, 10/28/12.

Punde TH, Wu WH, Lien PC, Shih PC, Chang MDT, Lee KY 等. A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process. 於 Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society. 2012. p. 1021-1023

Punde, Tushar Harishchandra ; Wu, Wen Hao ; Lien, Pei Chun 等. / A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process. Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, 2012. 頁 1021-1023

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title = "A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process",

abstract = "We report a 3D biomimetic microsystem which mimics lung microenvironment for monitoring the role of chemokine induced lung inflammation. The extravasation of fibrocytes in response to eosinophil cationic protein (ECP)-stimulated bronchial epithelial cells induced lung inflammation was mimicked on the micro-fluidic chip system for monitoring the microenvironmental changes.",

keywords = "Biomimetics, Bronchial asthma, Eosinophil cationic protein, Fibrocytes, Microfluidic chip",

author = "Punde, {Tushar Harishchandra} and Wu, {Wen Hao} and Lien, {Pei Chun} and Shih, {Po Chen} and Chang, {Margaret Dah Tsyr} and Lee, {Kang Yun} and Kuo, {Han Pin} and Liu, {Cheng Hsien}",

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AU - Punde, Tushar Harishchandra

AU - Wu, Wen Hao

AU - Lien, Pei Chun

AU - Shih, Po Chen

AU - Chang, Margaret Dah Tsyr

AU - Lee, Kang Yun

AU - Kuo, Han Pin

AU - Liu, Cheng Hsien

PY - 2012

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N2 - We report a 3D biomimetic microsystem which mimics lung microenvironment for monitoring the role of chemokine induced lung inflammation. The extravasation of fibrocytes in response to eosinophil cationic protein (ECP)-stimulated bronchial epithelial cells induced lung inflammation was mimicked on the micro-fluidic chip system for monitoring the microenvironmental changes.

AB - We report a 3D biomimetic microsystem which mimics lung microenvironment for monitoring the role of chemokine induced lung inflammation. The extravasation of fibrocytes in response to eosinophil cationic protein (ECP)-stimulated bronchial epithelial cells induced lung inflammation was mimicked on the micro-fluidic chip system for monitoring the microenvironmental changes.

KW - Biomimetics

KW - Bronchial asthma

KW - Eosinophil cationic protein

KW - Fibrocytes

KW - Microfluidic chip

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BT - Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

PB - Chemical and Biological Microsystems Society

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A bronchial epithelium-mimetic microfluidic chip system for investigating microenvironmental change-induced inflammatory process

摘要

其他

ASJC Scopus subject areas

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