每年專案
個人檔案
學歷
- 2000-2007 臺北醫學大學藥研所博士
- 1997-1999 臺北醫學大學藥學系碩士
- 1993-1997 臺北醫學院醫技系學士
經歷
- 2021.02- 臺北醫學大學臨床醫學研究所教授
- 2018.02-2021.01 臺北醫學大學臨床醫學研究所副教授
- 2018.02- 臺北醫學大學國際醫學研究碩士學位學程助理教授
- 2018.01-2014.07 中央研究院生物化學研究所博士後研究
- 2014.09-2018.01 臺北醫學大學臨床醫學研究所助理教授
獎項
- 2015 中央研究院基因體研究中心 訪問學者
- 2015 PLoS one期刊審查委員
- 2008, 2009及2013 Journal of Cellular Biochemistry期刊審查委員
研究興趣
- 癌症藥物研發
- 蛋白質交互作用
相關連結
指紋
- 1 類似的個人檔案
過去五年中的合作和熱門研究領域
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探討阻斷HSP27蛋白質間交互作用選擇性毒殺三陰性乳癌的分子機制和開發HSP27靶向的新型抗癌藥物(1/3)
Lin, Y.-F. (PI)
8/1/25 → 7/31/26
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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探討GBP5藉由發炎小體建構NF-κB依賴型回饋環線促進口腔鱗狀上皮細胞癌治療抗性、轉移與免疫抑制的分子機制
Lin, Y.-F. (PI)
8/1/24 → 7/31/25
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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探討AEBP1在促進多形性膠質母細胞瘤之 temozolomide抗藥性中的角色
Lin, Y.-F. (PI)
7/1/24 → 2/28/25
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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利用Iodoacetamide衍生物找尋與鑑定新型藥物標靶用於治療多型性神經膠質母細胞瘤
Lin, Y.-F. (PI)
7/1/22 → 2/28/23
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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利用人工智慧虛擬篩選平台鑑定DNA聚合酶theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(3/3)
Lin, Y.-F. (PI)
8/1/21 → 7/31/22
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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The IL-8/NF-κB feedback loop confers a paclitaxel-sensitive/doxorubicin-resistant phenotype in triple-negative breast cancer
Lin, H. Y., Wang, W. K., Lin, C. H., Kuei, C. H., Lee, H. H., Kent Lin, Y. H., Chiu, H. W. & Lin, Y. F., 10月 2025, 於: Free Radical Biology and Medicine. 238, p. 316-328 13 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma
Chiu, H. W., Lee, H. L., Lee, H. H., Lu, H. W., Lin, K. Y. H., Lin, Y. F. & Lin, C. H., 12月 2024, 於: Journal of Translational Medicine. 22, 1, 13.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取17 引文 斯高帕斯(Scopus) -
GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis
Wang, W. K., Lin, H. Y., Lin, C. H., Lee, H. H., Chen, Y. L., Lin, Y. H. K., Chiu, H. W., Sheen-Chen, S. M. & Lin, Y. F., 12月 2024, 於: Breast Cancer Research. 26, 1, 193.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取3 引文 斯高帕斯(Scopus) -
Guanylate binding protein 5 triggers NF-κB activation to foster radioresistance, metastatic progression and PD-L1 expression in oral squamous cell carcinoma
Chiu, H. W., Lin, C. H., Lee, H. H., Lu, H. W., Lin, Y. H. K., Lin, Y. F. & Lee, H. L., 2月 2024, 於: Clinical Immunology. 259, 109892.研究成果: 雜誌貢獻 › 文章 › 同行評審
8 引文 斯高帕斯(Scopus) -
AIM2 upregulation promotes metastatic progression and PD-L1 expression in lung adenocarcinoma
Zheng, J. Q., Lin, C. H., Lee, H. H., Chang, W. M., Li, L. J., Su, C. Y., Lee, K. Y., Chiu, H. W. & Lin, Y. F., 1月 2023, 於: Cancer Science. 114, 1, p. 306-320 15 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取22 引文 斯高帕斯(Scopus)
資料集
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Additional file 1: Table S1. of Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Chang, W.-M. (Creator), Hsiao, M. (Creator), Su, C.-Y. (Contributor), Chang, P.M.-H. (Creator), Lin, Y.-F. (Contributor), Wu, A. T. H. (Creator), Chen, C.-L. (Creator), Chi, L.-H. (Contributor), Chen, M.-H. (Creator) & Chang, Y.-C. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3660368_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3660368_d1.v1
資料集: Dataset
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Additional file 1: of Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Huang, M.-S. (Contributor), Jan, Y.-H. (Creator), Yang, C.-J. (Contributor), Hsiao, M. (Creator), Lin, Y.-F. (Creator) & Lai, T.-C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.7648181.v1, https://doi.org/10.6084%2Fm9.figshare.7648181.v1
資料集: Dataset
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Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Jan, Y.-H. (Creator), Lai, T.-C. (Contributor), Yang, C.-J. (Contributor), Lin, Y.-F. (Creator), Huang, M.-S. (Contributor) & Hsiao, M. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4383008.v1, https://doi.org/10.6084%2Fm9.figshare.c.4383008.v1
資料集: Dataset
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Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Chang, Y.-C. (Creator), Chi, L.-H. (Contributor), Chang, W.-M. (Creator), Su, C.-Y. (Contributor), Lin, Y.-F. (Contributor), Chen, C.-L. (Creator), Chen, M.-H. (Creator), Chang, P.M.-H. (Creator), Wu, A. T. H. (Creator) & Hsiao, M. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3660368.v1, https://figshare.com/collections/Glucose_transporter_4_promotes_head_and_neck_squamous_cell_carcinoma_metastasis_through_the_TRIM24-DDX58_axis/3660368/1
資料集: Dataset
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The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer
Huang, S.-P. (Contributor), Liu, P.-Y. (Contributor), Kuo, C.-J. (Contributor), Chen, C.-L. (Contributor), Lee, W.-J. (Contributor), Tsai, Y.-H. (Creator) & Lin, Y.-F. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3794620.v1, https://figshare.com/collections/The_G_h-PLC_1_signaling_axis_drives_metastatic_progression_in_triple-negative_breast_cancer/3794620/1
資料集: Dataset