Yuan-Chin Tsai

2023

Disruption of CCL2 in Mesenchymal Stem Cells as an Anti-Tumor Approach against Prostate Cancer

Bui, Q. T., Lee, K. D., Fan, Y. C., Lewis, B. S., Deng, L. W. & Tsai, Y. C., 1月 2023, 於: Cancers. 15, 2, 441.

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2021

Genetic variants in MAPK10 modify renal cell carcinoma susceptibility and clinical outcomes

Tsai, Y. C., Huang, C. Y., Hsueh, Y. M., Fan, Y. C., Fong, Y. C., Huang, S. P., Geng, J. H., Chen, L. C., Lu, T. L. & Bao, B. Y., 6月 15 2021, 於: Life Sciences. 275, 119396.

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1 引文斯高帕斯（Scopus）

Investigation of anti-tumor effects of an MLK1 inhibitor in prostate and pancreatic cancers

Fan, Y. C., Hsu, K. C., Lin, T. E., Zechner, D., Hsu, S. P. & Tsai, Y. C., 8月 2021, 於: Biology. 10, 8, 742.

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3 引文斯高帕斯（Scopus）

2020

Roles of interleukin-1 receptor antagonist in prostate cancer progression

Fan, Y. C., Lee, K. D. & Tsai, Y. C., 12月 2020, 於: Biomedicines. 8, 12, p. 1-13 13 p., 602.

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3 引文斯高帕斯（Scopus）

Tumor-infiltrating leukocytes suppress local inflammation via interleukin-1 receptor antagonist in a syngeneic prostate cancer model

Fan, Y. C., Chen, W. Y., Lee, K. D. & Tsai, Y. C., 4月 2020, 於: Biology. 9, 4, 67.

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3 引文斯高帕斯（Scopus）

2018

Androgen deprivation therapy-induced epithelial-mesenchymal transition of prostate cancer through downregulating SPDEF and activating CCL2

Tsai, Y. C., Chen, W. Y., Abou-Kheir, W., Zeng, T., Yin, J. J., Bahmad, H., Lee, Y. C. & Liu, Y. N., 5月 2018, 於: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 5, p. 1717-1727 11 p.

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36 引文斯高帕斯（Scopus）

A synergistic anti-cancer effect of troglitazone and lovastatin in a human anaplastic thyroid cancer cell line and in a mouse xenograft model

Zhong, W. B., Tsai, Y. C., Chin, L. H., Tseng, J. H., Tang, L. W., Horng, S., Fan, Y. C. & Hsu, S. P., 7月 1 2018, 於: International Journal of Molecular Sciences. 19, 7, 1834.

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17 引文斯高帕斯（Scopus）

Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer

Tsai, Y. C., Zeng, T., Abou-Kheir, W., Yeh, H. L., Yin, J. J., Lee, Y. C., Chen, W. Y. & Liu, Y. N., 2月 19 2018, 於: Molecular Cancer. 17, 1, p. 42 42.

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13 引文斯高帕斯（Scopus）

2017

Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6

Tsai, Y. C., Chen, W. Y., Siu, M. K., Tsai, H. Y., Yin, J. J., Huang, J. & Liu, Y. N., 1月 1 2017, 於: Cancer Letters. 384, p. 1-8 8 p.

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23 引文斯高帕斯（Scopus）

Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis

Chen, W. Y., Tsai, Y. C., Siu, M. K., Yeh, H. L., Chen, C. L., Yin, J. J., Huang, J. & Liu, Y. N., 11月 9 2017, 於: Oncogene. 36, 45, p. 6213-6224 12 p.

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26 引文斯高帕斯（Scopus）

Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer

Chen, W. Y., Tsai, Y. C., Yeh, H. L., Suau, F., Jiang, K. C., Shao, A. N., Huang, J. & Liu, Y. N., 8月 15 2017, 於: Science Signaling. 10, 492, eaam6826.

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42 引文斯高帕斯（Scopus）

New ideas in preventing castration-resistant prostate cancer

Tsai, Y. C. & Liu, Y. N., 10月 17 2017, 於: Oncotarget. 8, 49, p. 84628-84629 2 p.

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Simvastatin inhibits cell proliferation and migration in human anaplastic thyroid cancer

Chen, M. C., Tsai, Y. C., Tseng, J. H., Liou, J. J., Horng, S., Wen, H. C., Fan, Y. C., Zhong, W. B. & Hsu, S. P., 12月 13 2017, 於: International Journal of Molecular Sciences. 18, 12, 2690.

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18 引文斯高帕斯（Scopus）

TCF7 is suppressed by the androgen receptor via microRNA-1-mediated downregulation and is involved in the development of resistance to androgen deprivation in prostate cancer

Siu, M. K., Chen, W-Y., Tsai, H-Y., Chen, H-Y., Yin, J. J., Chen, C-L., Tsai, Y-C. & Liu, Y-N., 6月 2017, 於: Prostate Cancer and Prostatic Diseases. 20, 2, p. 172-178 7 p.

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21 引文斯高帕斯（Scopus）

2016

KLF4 functions as an activator of the androgen receptor through reciprocal feedback

Siu, M-K., Suau, F., Chen, W-Y., Tsai, Y-C., Tsai, H-Y., Yeh, H-L. & Liu, Y-N., 12月 2016, 於: Oncogenesis. 5, 12, p. e282

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18 引文斯高帕斯（Scopus）

2015

DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection

Rowles, D. L., Tsai, Y. C., Greco, T. M., Lin, A. E., Li, M., Yeh, J. & Cristea, I. M., 6月 1 2015, 於: Proteomics. 15, 12, p. 1968-1982 15 p.

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19 引文斯高帕斯（Scopus）

Transforming growth factor-β promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway

Siu, M. K., Tsai, Y. C., Chang, Y. S., Yin, J. J., Suau, F., Chen, W. Y. & Liu, Y. N., 9月 3 2015, 於: Oncogene. 34, 36, p. 4767-4776 10 p.

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70 引文斯高帕斯（Scopus）

2014

Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis

Tsai, Y. C., Greco, T. M. & Cristea, I. M., 2014, 於: Molecular and Cellular Proteomics. 13, 1, p. 73-83 11 p.

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89 引文斯高帕斯（Scopus）

2012

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription

Tsai, Y. C., Greco, T. M., Boonmee, A., Miteva, Y. & Cristea, I. M., 5月 2012, 於: Molecular and Cellular Proteomics. 11, 5, p. 60-76 17 p.

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98 引文斯高帕斯（Scopus）

2011

Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα

Lin, R. K., Zhou, N., Lyu, Y. L., Tsai, Y. C., Lu, C. H., Kerrigan, J., Chen, Y. T., Guan, Z., Hsieh, T. S. & Liu, L. F., 9月 23 2011, 於: Journal of Biological Chemistry. 286, 38, p. 33591-33600 10 p.

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40 引文斯高帕斯（Scopus）

2010

Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia

Azarova, A. M., Lin, R. K., Tsai, Y. C., Liu, L. F., Lin, C. P. & Lyu, Y. L., 8月 2010, 於: Biochemical and Biophysical Research Communications. 399, 1, p. 66-71 6 p.

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40 引文斯高帕斯（Scopus）

2009

12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents

Feng, W., Satyanarayana, M., Tsai, Y. C., Liu, A. A., Liu, L. F. & LaVoie, E. J., 4月 1 2009, 於: Bioorganic and Medicinal Chemistry. 17, 7, p. 2877-2885 9 p.

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18 引文斯高帕斯（Scopus）

A G-quadruplex stabilizer induces M-phase cell cycle arrest

Tsai, Y. C., Qi, H., Lin, C. P., Lin, R. K., Kerrigan, J. E., Rzuczek, S. G., LaVoie, E. J., Rice, J. E., Pilch, D. S., Lyu, Y. L. & Liu, L. F., 8月 21 2009, 於: Journal of Biological Chemistry. 284, 34, p. 22535-22543 9 p.

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45 引文斯高帕斯（Scopus）

Cytotoxicity and TOP1-targeting activity of 8- and 9-amino derivatives of 5-butyl- and 5-(2-N,N-dimethylamino)ethyl-5H-dibenzo[c,h][1,6]naphthyridin-6-ones

Sharma, L., Tsai, Y. C., Liu, A. A., Liu, L. F. & LaVoie, E. J., 4月 2009, 於: European Journal of Medicinal Chemistry. 44, 4, p. 1471-1476 6 p.

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10 引文斯高帕斯（Scopus）

Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide

Feng, W., Satyanarayana, M., Tsai, Y. C., Liu, A. A., Liu, L. F. & LaVoie, E. J., 9月 2009, 於: European Journal of Medicinal Chemistry. 44, 9, p. 3433-3438 6 p.

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20 引文斯高帕斯（Scopus）

2008

11-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine derivatives as novel topoisomerase I-targeting agents

Feng, W., Satyanarayana, M., Tsai, Y. C., Liu, A. A., Liu, L. F. & LaVoie, E. J., 9月 15 2008, 於: Bioorganic and Medicinal Chemistry. 16, 18, p. 8598-8606 9 p.

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11 引文斯高帕斯（Scopus）

A novel peroxisome proliferator-activated receptor α/γ agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells

Kao, Y. H., Hsieh, H. P., Chitlimalla, S. K., Pan, W. Y., Kuo, C. C., Tsai, Y. C., Lin, W. H., Chuang, S. E. & Chang, J. Y., 2月 2008, 於: Anti-Cancer Drugs. 19, 2, p. 151-158 8 p.

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6 引文斯高帕斯（Scopus）

Facile formation of hydrophilic derivatives of 5H-8,9-dimethoxy-5-[2-(N,N-dimethylamino)ethyl]-2,3-methylenedioxydibenzo[c,h] [1,6]naphthyridin-6-one (ARC-111) and its 12-aza analog via quaternary ammonium intermediates

Feng, W., Satyanarayana, M., Tsai, Y. C., Liu, A. A., Liu, L. F. & LaVoie, E. J., 6月 15 2008, 於: Bioorganic and Medicinal Chemistry Letters. 18, 12, p. 3570-3572 3 p.

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12 引文斯高帕斯（Scopus）

Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9-methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31)

Satyanarayana, M., Feng, W., Cheng, L., Liu, A. A., Tsai, Y. C., Liu, L. F. & LaVoie, E. J., 8月 15 2008, 於: Bioorganic and Medicinal Chemistry. 16, 16, p. 7824-7831 8 p.

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17 引文斯高帕斯（Scopus）

Synthesis of N-substituted 5-[2-(N-alkylamino)ethyl]dibenzo[c,h][1,6]naphthyridines as novel topoisomerase I-targeting antitumor agents

Feng, W., Satyanarayana, M., Cheng, L., Liu, A., Tsai, Y. C., Liu, L. F. & LaVoie, E. J., 10月 15 2008, 於: Bioorganic and Medicinal Chemistry. 16, 20, p. 9295-9301 7 p.

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16 引文斯高帕斯（Scopus）

2007

Protection of DNA ends by telomeric 3′ G-tail sequences

Tsai, Y. C., Qi, H. & Liu, L. F., 6月 29 2007, 於: Journal of Biological Chemistry. 282, 26, p. 18786-18792 7 p.

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18 引文斯高帕斯（Scopus）

Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies

Azarova, A. M., Lyu, Y. L., Lin, C. P., Tsai, Y. C., Lau, J. Y. N., Wang, J. C. & Liu, L. F., 6月 26 2007, 於: Proceedings of the National Academy of Sciences of the United States of America. 104, 26, p. 11014-11019 6 p.

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236 引文斯高帕斯（Scopus）

Topoisomerase IIβ-mediated DNA double-strand breaks: Implications in doxorubicin cardiotoxicity and prevention by dexrazoxane

Yi, L. L., Kerrigan, J. E., Lin, C. P., Azarova, A. M., Tsai, Y. C., Ban, Y. & Liu, L. F., 9月 15 2007, 於: Cancer Research. 67, 18, p. 8839-8846 8 p.

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468 引文斯高帕斯（Scopus）

2006

G-quadruplexes induce apoptosis in tumor cells

Qi, H., Lin, C. P., Fu, X., Wood, L. M., Liu, A. A., Tsai, Y. C., Chen, Y., Barbieri, C. M., Pilch, D. S. & Liu, L. F., 12月 15 2006, 於: Cancer Research. 66, 24, p. 11808-11816 9 p.

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64 引文斯高帕斯（Scopus）

2004

Inhibition of hepatitis C virus replication by arsenic trioxide

Hwang, D. R., Tsai, Y. C., Lee, J. C., Huang, K. K., Lin, R. K., Ho, C. H., Chiou, J. M., Lin, Y. T., Hsu, J. T. A. & Yeh, C. T., 8月 2004, 於: Antimicrobial Agents and Chemotherapy. 48, 8, p. 2876-2882 7 p.

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36 引文斯高帕斯（Scopus）

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