陳 奕平

研究成果

每年研究成果 2005 2005 2007 2013 2014 2015 2016 2018 2019 2020 2023

• 25 文章
• 1 書籍
• 1 會議貢獻

每年研究成果

每年研究成果

搜尋結果

• 2023

  Overcoming Cytosolic Delivery Barriers of Proteins Using Denatured Protein-Conjugated Mesoporous Silica Nanoparticles

  Dembélé, J., Liao, J. H., Liu, T. P. & Chen, Y. P., 1月 2023, 於: ACS Applied Materials and Interfaces. 15, 1, p. 432-451 20 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Conjugated Protein 100%
  • Silica nanoparticles 98%
  • Silicon Dioxide 74%
  • Superoxide Dismutase 72%
  • Proteins 59%
  2 引文 斯高帕斯（Scopus）
• 2022

  Bridging Size and Charge Effects of Mesoporous Silica Nanoparticles for Crossing the Blood–Brain Barrier

  Chen, Y. P., Chou, C. M., Chang, T. Y., Ting, H., Dembélé, J., Chu, Y. T., Liu, T. P., Changou, C. A., Liu, C. W. & Chen, C. T., 6月 27 2022, 於: Frontiers in Chemistry. 10, 931584.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Size Effect 100%
  • Nanoparticle 44%
  • Doxorubicin 30%
  • Drug 20%
  • Protein 12%
  5 引文 斯高帕斯（Scopus）
• 2020

  Catcher in the rel: Nanoparticles-antibody conjugate as NF-κB nuclear translocation blocker

  Chen, Y. P., Chen, C. T., Liu, T. P., Chien, F. C., Wu, S. H., Chen, P. & Mou, C. Y., 7月 2020, 於: Biomaterials. 246, 119997.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Transcription factors 100%
  • Antibodies 88%
  • Silica nanoparticles 70%
  • Nanoparticles 68%
  • Proteins 63%
  15 引文 斯高帕斯（Scopus）

• STING Activator c-di-GMP-Loaded Mesoporous Silica Nanoparticles Enhance Immunotherapy against Breast Cancer

  Chen, Y. P., Xu, L., Tang, T. W., Chen, C. H., Zheng, Q. H., Liu, T. P., Mou, C. Y., Wu, C. H. & Wu, S. H., 12月 23 2020, 於: ACS Applied Materials and Interfaces. 12, 51, p. 56741-56752 12 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Interferons 100%
  • Rhodamine B Isothiocyanate 93%
  • Silica nanoparticles 84%
  • Growth Inhibition 66%
  • Clearance 60%
  40 引文 斯高帕斯（Scopus）
• 2019

  Codelivery of Plasmid and Curcumin with Mesoporous Silica Nanoparticles for Promoting Neurite Outgrowth

  Cheng, C. S., Liu, T. P., Chien, F. C., Mou, C. Y., Wu, S. H. & Chen, Y. P., 5月 1 2019, 於: ACS Applied Materials and Interfaces. 11, 17, p. 15322-15331 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Silica nanoparticles 100%
  • Curcumin 75%
  • Neurodegenerative diseases 59%
  • Reactive oxygen species 47%
  • Oxidative stress 45%
  44 引文 斯高帕斯（Scopus）

• Critical Features for Mesoporous Silica Nanoparticles Encapsulated into Erythrocytes

  Chen, Z. A., Wu, S. H., Chen, P., Chen, Y. P. & Mou, C. Y., 2月 6 2019, 於: ACS Applied Materials and Interfaces. 11, 5, p. 4790-4798 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Silica nanoparticles 100%
  • Nanoparticle 33%
  • Blood 24%
  • Encapsulation 22%
  • Red 13%
  30 引文 斯高帕斯（Scopus）
• 2018

  Horseradish Peroxidase-Encapsulated Hollow Silica Nanospheres for Intracellular Sensing of Reactive Oxygen Species

  Chen, H-Y., Wu, S-H., Chen, C-T., Chen, Y-P., Chang, F-P., Chien, F-C. & Mou, C-Y., 4月 24 2018, 於: Nanoscale Research Letters. 13, 1, p. 123

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Reactive oxygen species 100%
  • Nanospheres 93%
  • Silica 57%
  • Nanosphere 54%
  • Reactive Oxygen Metabolite 52%
  8 引文 斯高帕斯（Scopus）

• The Bioimaging Applications of Mesoporous Silica Nanoparticles: Enzymes

  Pratiwi, F. W., Kuo, C. W., Wu, S-H., Chen, Y-P., Mou, C. Y., Chen, P. & F., T. (編輯), 1月 1 2018, International Academic Press. 31 p. (Enzymes; 卷 43)

  研究成果: 报告类型 › 書籍

  • Fluorescence 100%
  • Nanoparticle 86%
  • Application 54%
  • Dye 36%
  • Contrast Medium 32%
  12 引文 斯高帕斯（Scopus）
• 2017

  Impacts of Cross-Linkers on Biological Effects of Mesoporous Silica Nanoparticles

  Chen, Y. P., Wu, S. H., Chen, I. C. & Chen, C. T., 3月 22 2017, 於: ACS Applied Materials and Interfaces. 9, 11, p. 10254-10265 12 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Silica nanoparticles 100%
  • Nanoparticles 65%
  • Esters 36%
  • Nanoparticle 33%
  • Cytotoxicity 32%
  16 引文 斯高帕斯（Scopus）
• 2016

  Approach to Deliver Two Antioxidant Enzymes with Mesoporous Silica Nanoparticles into Cells

  Lin, Y. H., Chen, Y. P., Liu, T. P., Chien, F. C., Chou, C. M., Chen, C. T. & Mou, C. Y., 7月 20 2016, 於: ACS Applied Materials and Interfaces. 8, 28, p. 17944-17954 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Silica nanoparticles 100%
  • Antioxidants 89%
  • Enzymes 76%
  • Reactive oxygen species 58%
  • Antioxidant Agent 50%
  55 引文 斯高帕斯（Scopus）

• Therapeutic evaluation of HIV transduction basic domain-conjugated superoxide dismutase solution on suppressive effects of the formation of peroxynitrite and expression of COX-2 in murine skin

  Liu, T. P., Chen, Y. P., Chou, C. M., Chiu, T. T. & Chen, C. T., 1月 20 2016, 於: Journal of Biomedical Science. 23, 1, 11.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Peroxynitrous Acid 100%
  • Peroxynitrite 98%
  • Cyclooxygenase 2 82%
  • Superoxide 77%
  • Reactive Oxygen Metabolite 74%
  4 引文 斯高帕斯（Scopus）
• 2015

  Attenuating HIV Tat/TAR-mediated protein expression by exploring the side chain length of positively charged residues

  Wu, C. H., Chen, Y-P., Liu, S. L., Chien, F. C., Mou, C. Y. & Cheng, R. P., 2015, 於: Organic and Biomolecular Chemistry. 13, 45, p. 11096-11104 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • human immunodeficiency virus 100%
  • peptides 75%
  • proteins 54%
  • RNA 47%
  • HIV 47%
  4 引文 斯高帕斯（Scopus）

• Biosafety evaluations of well-dispersed mesoporous silica nanoparticles: Towards in vivo-relevant conditions

  Liu, T. P., Wu, S. H., Chen, Y. P., Chou, C. M. & Chen, C. T., 4月 21 2015, 於: Nanoscale. 7, 15, p. 6471-6480 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Containment of Biohazards 100%
  • Silica nanoparticles 86%
  • Nanoparticles 45%
  • Proteins 42%
  • Nanoparticle 28%
  40 引文 斯高帕斯（Scopus）

• Local pH tracking in living cells

  Tsou, C. J., Hsia, C. H., Chu, J. Y., Hung, Y., Chen, Y-P., Chien, F. C., Chou, K. C., Chen, P. & Mou, C. Y., 3月 7 2015, 於: Nanoscale. 7, 9, p. 4217-4225 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Silica nanoparticles 100%
  • Cells 64%
  • Nanoparticle 33%
  • pH Value 27%
  • Nanosystems 17%
  15 引文 斯高帕斯（Scopus）
• 2014

  Carbon dots prepared from ginger exhibiting efficient inhibition of human hepatocellular carcinoma cells

  Li, C. L., Ou, C. M., Huang, C. C., Wu, W. C., Chen, Y. P., Lin, T. E., Ho, L. C., Wang, C. W., Shih, C. C., Zhou, H. C., Lee, Y. C., Tzeng, W. F., Chiou, T. J., Chu, S. T., Cang, J. & Chang, H. T., 7月 28 2014, 於: Journal of Materials Chemistry B. 2, 28, p. 4564-4571 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Ginger 100%
  • Hep G2 Cells 77%
  • Cytometry 76%
  • Carbon 72%
  • Cells 70%
  244 引文 斯高帕斯（Scopus）

• Intracellular implantation of enzymes in hollow silica Nanospheres for protein therapy: Cascade System of Superoxide Dismutase and Catalase

  Chang, F. P., Chen, Y-P. & Mou, C. Y., 11月 26 2014, 於: Small. 10, 22, p. 4785-4795 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Superoxide Dismutase 100%
  • Nanospheres 85%
  • Enzymes 58%
  • Silicon Dioxide 58%
  • Silica 52%
  78 引文 斯高帕斯（Scopus）
• 2013

  Altering the Tat-derived peptide bioactivity landscape by changing the arginine side chain length

  Wu, C. H., Chen, Y-P., Mou, C. Y. & Cheng, R. P., 2月 2013, 於: Amino Acids. 44, 2, p. 473-480 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Arginine 100%
  • Bioactivity 71%
  • Amino Acids 70%
  • Peptides 63%
  • Length 59%
  12 引文 斯高帕斯（Scopus）

• A new strategy for intracellular delivery of enzyme using mesoporous silica nanoparticles: Superoxide dismutase

  Chen, Y. P., Chen, C. T., Hung, Y., Chou, C. M., Liu, T. P., Liang, M. R., Chen, C. T. & Mou, C. Y., 1月 30 2013, 於: Journal of the American Chemical Society. 135, 4, p. 1516-1523 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Superoxide Dismutase 100%
  • Silica nanoparticles 77%
  • Enzymes 58%
  • Silicon Dioxide 58%
  • Trans-Activators 51%
  136 引文 斯高帕斯（Scopus）

• Enhanced non-endocytotic uptake of mesoporous silica nanoparticles by shortening the peptide transporter arginine side Chain

  Wu, C. H., Chen, Y-P., Wu, S-H., Hung, Y., Mou, C. Y. & Cheng, R. P., 12月 11 2013, 於: ACS Applied Materials and Interfaces. 5, 23, p. 12244-12248 5 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Arginine 100%
  • peptide permease 88%
  • Silica nanoparticles 86%
  • Peptides 74%
  • Silicon Dioxide 64%
  20 引文 斯高帕斯（Scopus）

• Protection of HeLa cells against ROS stress by CuZnSOD mimic system

  Fang, Y. C., Chen, Y-P., Chen, C-T., Lin, T. S. & Mou, C. Y., 11月 28 2013, 於: Journal of Materials Chemistry B. 1, 44, p. 6042-6052 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Silica nanoparticles 100%
  • Silicon Dioxide 75%
  • Fluorescein 70%
  • isothiocyanic acid 69%
  • HeLa Cells 66%
  11 引文 斯高帕斯（Scopus）
• 2012

  Surface charge effect in intracellular localization of mesoporous silica nanoparticles as probed by fluorescent ratiometric pH imaging

  Chen, Y-P., Chen, H. A., Hung, Y., Chien, F. C., Chen, P. & Mou, C. Y., 2月 7 2012, 於: RSC Advances. 2, 3, p. 968-973 6 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Silica nanoparticles 100%
  • Surface charge 94%
  • Imaging techniques 50%
  • Nanoparticle 33%
  • pH Value 27%
  58 引文 斯高帕斯（Scopus）
• 2010

  Comparative metabolomics approach coupled with cell- and gene-based assays for species classification and anti-inflammatory bioactivity validation of Echinacea plants

  Hou, C. C., Chen, C. H., Yang, N. S., Chen, Y. P., Lo, C. P., Wang, S. Y., Tien, Y. J., Tsai, P. W. & Shyur, L. F., 11月 2010, 於: Journal of Nutritional Biochemistry. 21, 11, p. 1045-1059 15 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Echinacea 100%
  • Metabolomics 70%
  • Antiinflammatory 60%
  • Anti-Inflammatory Agents 46%
  • Bioactivity 45%
  51 引文 斯高帕斯（Scopus）
• 2008

  Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators

  Shyur, L. F., Huang, C. C., Lo, C. P., Chiu, C. Y., Chen, Y. P., Wang, S. Y. & Chang, S. T., 4月 2008, 於: Phytochemistry. 69, 6, p. 1348-1358 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Cryptomeria 100%
  • Hepatoprotective 90%
  • Cryptomeria japonica 80%
  • Antiinflammatory 61%
  • Tracheophyta 38%
  50 引文 斯高帕斯（Scopus）
• 2007

  A galactolipid possesses novel cancer chemopreventive effects by suppressing inflammatory mediators and mouse B16 melanoma

  Hou, C. C., Chen, Y. P., Wu, J. H., Huang, C. C., Wang, S. Y., Yang, N. S. & Shyur, L. F., 7月 15 2007, 於: Cancer Research. 67, 14, p. 6907-6915 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • isofloridoside 100%
  • Galactolipids 76%
  • Experimental Melanomas 54%
  • Cyclooxygenase 2 19%
  • Neoplasms 14%
  67 引文 斯高帕斯（Scopus）

• In vivo protein transduction: Penetration of the biologically active HIV-1 tat mediated Cu,Zn-superoxide dismutase rescues murine skin from oxidative stress

  Liu, T. P., Chen, Y. P., Chou, C. M., Chang, Y. C., Chiu, T. T. & Chen, C. T., 2007, 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings. 卷 2. p. 417-420 4 p.

  研究成果: 書貢獻/報告類型 › 會議貢獻

  • Superoxide Dismutase 100%
  • Oxidative stress 89%
  • Reactive oxygen species 54%
  • Proteins 46%
  • Skin 44%
• 2005

  Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE ₂ in vitro or in mouse skin

  Chiang, Y. M., Lo, C. P., Chen, Y. P., Wang, S. Y., Yang, N. S., Kuo, Y. H. & Shyur, L. F., 10月 2005, 於: British Journal of Pharmacology. 146, 3, p. 352-363 12 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • ethyl caffeate 100%
  • Prostaglandins E 61%
  • Nitric Oxide Synthase Type II 52%
  • Transcription Factors 37%
  • Skin 27%
  147 引文 斯高帕斯（Scopus）

• Identification of three mutations in the Cu,Zn-superoxide dismutase (Cu,Zn-SOD) gene with familial amyotrophic lateral sclerosis: Transduction of human Cu,Zn-SOD into PC12 cells by HIV-1 TAT protein basic domain

  Chou, C. M., Huang, C. J., Shih, C. M., Chen, Y. P., Liu, T. P. & Chen, C. T., 2005, 於: Annals of the New York Academy of Sciences. 1042, p. 303-313 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Amyotrophic Lateral Sclerosis 100%
  • Transduction 83%
  • Amyotrophic lateral sclerosis 1 82%
  • Superoxide Dismutase-1 78%
  • Trans-Activators 75%
  13 引文 斯高帕斯（Scopus）