每年專案
個人檔案
學歷
- 2014 國立成功大學生物資訊與訊息傳遞研究所博士
- 2009 國立成功大學生物資訊研究所碩士
- 2007 國立嘉義大學生物農業科技學系學士
經歷
- 2021.06- 臺北醫學大學神經醫學研究中心助理研究員
- 2017.04-2021.05 臺北醫學大學醫學科學研究所博士後研究員
- 2016.03-2017.03 國立交通大學生物科技學系博士後研究員
- 2015.03-2016.03 國家衛生研究院國家環境醫學研究所博士後研究員
獎項
- 2019.05 Exhibition of Excellent Poster by the 34th Joint Annual Conference of Biomedical Science
- 2013.11 Exhibition of Excellent Poster by the 3rd International Symposium on Infectious Disease and Signal Transduction
研究興趣
- 分子生物學
- 細胞生物學
- 癌症生物學
- 生物資訊學
- 大數據分析
其它
Skills
- Interdisciplinary Considerations (biomedicine and computational science).
- Design the experiment independently and do the troubleshooting with colleagues.
- Confidently report information and research findings in writing.
- Patent analysis and patent portfolio.
- Big Data analytics and bioinformatics: Single-cell analysis (including scATAC-seq and scRNA-seq) using Cell Ranger and R language (Seurat package), high-throughput sequence analysis (RNA-seq, DNA methylation and cDNA microarray) using CLC Genomics Workbench and R language, functional analysis using MetaCore and Ingenuity Pathway Analysis, writing and editing a C program, and constructing a local MySQL relational database.
- Drug discovery: Post processing of protein-compound docking for structure-based drug discovery and development, systemic approaches to identify potential targets and drugs for drug repositioning in several diseases.
- Biochemistry and Molecular Biology: Protein purification from coli, western blot, plasmid construction, isolation and purification of genomic DNA, mRNA and microRNA, real-time PCR, agarose gel electrophoresis, SNP technology, and yeast two-hybrid screening.
- Cell Biology: Cell-related assays techniques (such as cell culture), microscopy imaging techniques (using confocal and time-lapse microscopy), and flow cytometry.
- Animal model: Zebrafish model, xenograft, metastasis, TBI, and orthotopic GBM mice model.
- Proteomics: Desalting and Mass Spectrometry (LTQ Orbitrap LC-MS/MS system), including in-gel or in-solution protein digestion, purification, MS/MS analysis, and analysis of proteomics data.
指紋
查看啟用 Wen-Bin Yang 的研究主題。這些主題標籤來自此人的作品。共同形成了獨特的指紋。
- 1 類似的個人檔案
網路
國家/地區層面的近期外部共同作業。按一下圓點深入探索詳細資料，或
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CCAAT/Enhancer-Binding Protein Delta Regulates Glioblastoma Survival through Catalase-Mediated Hydrogen Peroxide Clearance
Lin, H. Y., Lim, S. W., Hsu, T. I., Yang, W. B., Huang, C. C., Tsai, Y. T., Chang, W. C. & Ko, C. Y., 2022, 於: Oxidative Medicine and Cellular Longevity. 2022, 4081380.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression
Young, M. J., Chen, Y. C., Wang, S. A., Chang, H. P., Yang, W. B., Lee, C. C., Liu, C. Y., Tseng, Y. L., Wang, Y. C., Sun, H. S., Chang, W. C. & Hung, J. J., 1月 17 2022, 於: Journal of Biomedical Science. 29, 1, p. 3 3.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取3 引文 斯高帕斯（Scopus） -
HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells
Wu, A. C., Yang, W. B., Chang, K. Y., Lee, J. S., Liou, J. P., Su, R. Y., Cheng, S. M., Hwang, D. Y., Kikkawa, U., Hsu, T. I., Wang, C. Y., Chang, W. C., Chen, P. Y. & Chuang, J. Y., 12月 2022, 於: Journal of Experimental and Clinical Cancer Research. 41, 1, 47.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取5 引文 斯高帕斯（Scopus） -
Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y. T., Lo, W. L., Chen, P. Y., Ko, C. Y., Chuang, J. Y., Kao, T. J., Yang, W. B., Chang, K. Y., Hung, C. Y., Kikkawa, U., Chang, W. C. & Hsu, T. I., 3月 25 2022, 於: Journal of Biomedical Science. 29, 1, p. 21 21.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取10 引文 斯高帕斯（Scopus） -
SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma
Chien, C. H., Yang, W. B., Chuang, J. Y., Lee, J. S., Liao, W. A., Huang, C. Y., Chen, P. Y., Wu, A. C., Yang, S. T., Lai, C. C., Chi, P. I., Chu, J. M., Cheng, S. M., Liu, C. C., Hwang, D. Y., Chen, S. H. & Chang, K. Y., 12月 2022, 於: Journal of Experimental and Clinical Cancer Research. 41, 1, 220.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取
資料集
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MOESM3 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Liu, J. (Creator), Hsu, T. (Contributor), Chou, S. (Creator), Chuang, J. (Creator), Yang, W. (Creator), Chen, P. (Contributor), Chen, S. (Contributor), Yang, S. (Creator), Chu, J. (Contributor), Huang, C. (Contributor), Yang, K. (Creator), Chien, C. (Contributor), Chung, P. (Contributor), Lo, W. (Creator), Liu, M. (Creator) & Chang, K. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10006856.v1, https://doi.org/10.6084%2Fm9.figshare.10006856.v1
資料集: Dataset
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Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y. (Creator), Lo, W. (Creator), Chen, P. (Creator), Ko, C. (Creator), Chuang, J. (Creator), Kao, T. (Creator), Yang, W. (Creator), Chang, K. (Creator), Hung, C. (Creator), Kikkawa, U. (Creator), Chang, W. (Creator) & Hsu, T. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5916320.v1, https://springernature.figshare.com/collections/Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/5916320/1
資料集: Dataset
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MOESM5 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Liu, J. (Creator), Chen, P. (Contributor), Chen, S. (Contributor), Chu, J. (Contributor), Chien, C. (Contributor), Yang, W. (Creator), Lo, W. (Creator), Hsu, T. (Contributor), Yang, K. (Creator), Chung, P. (Contributor), Chou, S. (Creator), Chang, K. (Contributor), Yang, S. (Creator), Chuang, J. (Creator), Huang, C. (Contributor) & Liu, M. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006868.v1, https://doi.org/10.6084%2Fm9.figshare.10006868.v1
資料集: Dataset
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MOESM6 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chuang, J. (Creator), Chen, S. (Contributor), Yang, K. (Creator), Chien, C. (Contributor), Liu, J. (Creator), Hsu, T. (Contributor), Chang, K. (Contributor), Yang, S. (Creator), Chu, J. (Contributor), Chou, S. (Creator), Lo, W. (Creator), Liu, M. (Creator), Huang, C. (Contributor), Yang, W. (Creator), Chen, P. (Contributor) & Chung, P. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10006874.v1, https://doi.org/10.6084%2Fm9.figshare.10006874.v1
資料集: Dataset
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Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chien, C. (Contributor), Chuang, J. (Creator), Yang, S. (Creator), Yang, W. (Creator), Chen, P. (Contributor), Hsu, T. (Contributor), Huang, C. (Contributor), Lo, W. (Creator), Yang, K. (Creator), Liu, M. (Creator), Chu, J. (Contributor), Chung, P. (Contributor), Liu, J. (Creator), Chou, S. (Creator), Chen, S. (Contributor) & Chang, K. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4705370.v1, https://doi.org/10.6084%2Fm9.figshare.c.4705370.v1
資料集: Dataset