每年專案
個人檔案
學歷
- 2008 中山醫學大學生化暨生物科技研究所博士
- 2004 中山醫學大學生物化學研究所碩士
經歷
- 2025.07 臺北市立萬芳醫院研究部副主任
- 2021.02- 臺北醫學大學醫學系泌尿學科副教授
- 2015.11-2021.01 臺北醫學大學醫學系泌尿學科助理教授
- 2013.04- 臺北市立萬芳醫院研究部醫學研究員
- 2012.08-2013.03 衛生署立桃園醫院心臟科約用研究助理
- 2008.08-2011.07 臺灣大學醫學院毒理學研究所博士後研究員
研究興趣
- 醫學之生化及分子生物
- 藥理及毒理
獎項
- 2015 萬芳醫學中心論文獎(第二名)
與 UN SDG 相關的專業知識
聯合國會員國於 2015 年同意 17 項全球永續發展目標 (SDG),以終結貧困、保護地球並確保全體的興盛繁榮。此人的作品有助於以下永續發展目標:
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SDG 3 良好的健康和福祉
指紋
- 1 類似的個人檔案
過去五年中的合作和熱門研究領域
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研究牛樟芝衍生物 Antroquinonol 阻斷腎細胞癌中 L1CAM/RET 誘導的抗藥性和免疫抑制作用的治療效果和分子機制:以抗藥性腎細胞癌為標的之轉譯醫學研究(3/3)
Lee, W.-J. (PI)
8/1/26 → 7/31/27
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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研究牛樟芝衍生物 Antroquinonol 阻斷腎細胞癌中 L1CAM/RET 誘導的抗藥性和免疫抑制作用的治療效果和分子機制:以抗藥性腎細胞癌為標的之轉譯醫學研究
Lee, W.-J. (PI)
8/1/24 → 7/31/27
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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研究牛樟芝衍生物 Antroquinonol 阻斷腎細胞癌中 L1CAM/RET 誘導的抗藥性和免疫抑制作用的治療效果和分子機制:以抗藥性腎細胞癌為標的之轉譯醫學研究(2/3)
Lee, W.-J. (PI)
8/1/25 → 7/31/26
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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闡明SPOCK1/PI3K/AKT訊息路徑在透明細胞腎細胞癌對舒尼替尼抗藥性的潛在機制
Lee, W.-J. (PI)
8/1/20 → 7/1/21
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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Programmable local immunochemotherapy for triple-negative breast cancer via spatiotemporally controlled release of CpG oligodeoxynucleotides, gemcitabine, and paclitaxel
Hsieh, C. H., Hsu, M. Y., Lin, C. F., Liu, C. C., Kuo, Y. H., Huang, Y. T., Chen, W. Y., Liu, S. J. & Lee, W. J., 12月 2026, 於: npj Breast Cancer. 12, 1, 45.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取1 連結會在新分頁中打開 引文 斯高帕斯(Scopus) -
Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma
Ding, Y. F., Ho, K. H., Lee, W. J., Chen, L. H., Hsieh, F. K., Tung, M. C., Lin, S. H., Hsiao, M., Yang, S. F., Yang, Y. C. & Chien, M. H., 12月 2025, 於: Cell Death and Disease. 16, 1, 191.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取10 連結會在新分頁中打開 引文 斯高帕斯(Scopus) -
MAOB promotes ROS-mediated DNA damage, triggering a cyclic MAOB-HNF1A-53BP1-p53 axis that suppresses the malignancy of clear cell renal cell carcinoma
Ho, K. H., Lin, Y. W., Huang, H. C., Lai, F. R., Yang, Y. C., Lai, C. H., Wen, Y. C., Hsieh, F. K., Lee, W. J. & Chien, M. H., 12月 1 2025, 於: Redox Biology. 88, p. 103945 1 p., 103945.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取4 連結會在新分頁中打開 引文 斯高帕斯(Scopus) -
The off‑target effect of loratadine triggers autophagy‑mediated apoptosis in lung adenocarcinoma cells by deactivating JNK, p38, and STAT3 signaling through both PP2A‑dependent and independent pathways
Chien, M. H., Hung, W. Y., Lai, T. C., Tsai, C. H., Lee, K. L., Hsieh, F. K., Lee, W. J. & Chang, J. H., 4月 2025, 於: International Journal of Molecular Medicine. 55, 4, 54.研究成果: 雜誌貢獻 › 文章 › 同行評審
8 連結會在新分頁中打開 引文 斯高帕斯(Scopus) -
Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma
Chien, M. H., Yang, Y. C., Ho, K. H., Ding, Y. F., Chen, L. H., Chiu, W. K., Chen, J. Q., Tung, M. C., Hsiao, M. & Lee, W. J., 1月 2024, 於: Cell Death and Disease. 15, 1, p. 82 82.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取21 連結會在新分頁中打開 引文 斯高帕斯(Scopus)
資料集
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Additional file 1: of Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses
Cheng, C.-W. (Contributor), Chow, J.-M. (Contributor), Lee, W.-J. (Contributor), Chen, W.-S. (Contributor), Yang, Y.-C. (Contributor), Hung, W.-Y. (Contributor), Chang, J.-H. (Contributor), Hsiao, M. (Creator), Chen, P.-S. (Contributor) & Chien, M.-H. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.6999656.v1, https://doi.org/10.6084%2Fm9.figshare.6999656.v1
資料集: Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J.-M. (Contributor), Hsieh, Y.-H. (Contributor), Chen, C.-K. (Contributor), Lee, W.-J. (Contributor), Hsieh, F.-K. (Contributor), Yu, N.-Y. (Contributor), Chou, M.-C. (Contributor), Cheng, C.-W. (Contributor), Yang, S.-F. (Contributor) & Chien, M.-H. (Contributor), Figshare, 2015
DOI: 10.6084/m9.figshare.1568934.v1, https://figshare.com/articles/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/1
資料集: Dataset
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Additional file 1: of Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
Huang, H.-C. (Contributor), Lin, Y.-W. (Contributor), Wen, Y.-C. (Contributor), Lee, W.-J. (Contributor), Yang, Y.-C. (Contributor), Chang, J.-L. (Contributor), Chien, M.-H. (Contributor) & Hsiao, M. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.8252111.v1, https://doi.org/10.6084%2Fm9.figshare.8252111.v1
資料集: Dataset
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Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
Wu, S.-Y. (Contributor), Wen, Y.-C. (Contributor), Ku, C.-C. (Creator), Yang, Y.-C. (Contributor), Chow, J.-M. (Contributor), Yang, S.-F. (Contributor), Lee, W.-J. (Contributor) & Chien, M.-H. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4650602.v1, https://springernature.figshare.com/collections/Penfluridol_triggers_cytoprotective_autophagy_and_cellular_apoptosis_through_ROS_induction_and_activation_of_the_PP2A-modulated_MAPK_pathway_in_acute_myeloid_leukemia_with_different_FLT3_statuses/4650602/1
資料集: Dataset
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Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses
Chang, J.-H. (Contributor), Cheng, C.-W. (Contributor), Yang, Y.-C. (Contributor), Chen, W.-S. (Contributor), Hung, W.-Y. (Contributor), Chow, J.-M. (Contributor), Chen, P.-S. (Contributor), Hsiao, M. (Creator), Lee, W.-J. (Contributor) & Chien, M.-H. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4207865.v1, https://doi.org/10.6084%2Fm9.figshare.c.4207865.v1
資料集: Dataset