每年專案
個人檔案
學歷
- 2002 臺灣大學藥學研究所博士
- 1995 臺灣大學藥學研究所碩士
- 1992 臺北醫學大學藥學系學士
經歷
- 2019.11- 臺北醫學大學藥物科學學科教授
- 2019.08- 臺北醫學大學藥物科學學科主任
- 2017.08- 臺北醫學大學藥學院生藥學研究所教授
- 2013.08- 臺北醫學大學中草藥臨床藥物研發博士學位學程
- 2011.08-2017.07 臺北醫學大學藥學院生藥學研究所副教授
- 2007.08-2011.07 臺北醫學大學藥學院生藥學研究所助理教授
- 2004.08-2007.07 長庚科技大學助理教授
- 2003.09-2004.07 清華大學化學系博士後研究
- 2002.08-2003.08 臺大醫學院藥物研究中心博士後研究
研究興趣
- 天然物化學
- 有機合成
- 藥物化學
指紋
- 1 類似的個人檔案
過去五年中的合作和熱門研究領域
-
設計與合成新穎週期蛋白依賴性激酶8(CDK8)抑制劑作為具治療特發性肺纖維化潛力先導化合物(1/3)
Huang, W.-J. (PI)
8/1/24 → 7/31/25
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
-
-
結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(3/3)
Huang, W.-J. (PI)
8/1/23 → 7/31/24
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
-
結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(2/3)
Huang, W.-J. (PI)
8/1/22 → 7/31/23
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
-
結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(1/3)
Huang, W.-J. (PI)
8/1/21 → 7/31/22
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
-
CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcinoma
Lee, K. L., Liu, J. J., Huang, W. J., Hung, C. S. & Liang, Y. C., 12月 2025, 於: Cancer Cell International. 25, 1, 56.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
Discovery and biological evaluation of potent 2-trifluoromethyl acrylamide warhead-containing inhibitors of protein disulfide isomerase
Chu, J. C., Tsai, K. C., Wang, T. Y., Chen, T. Y., Tsai, J. Y., Lee, T., Lin, M. H., Hsieh, Y. S. Y., Wu, C. C. & Huang, W. J., 2月 5 2025, 於: European Journal of Medicinal Chemistry. 283, p. 117169 117169.研究成果: 雜誌貢獻 › 文章 › 同行評審
1 引文 斯高帕斯(Scopus) -
Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening
Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., 1月 13 2025, 於: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
The Cyclin-Dependent Kinase 8 Inhibitor E966–0530–45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo
Chou, C. H., Huang, W. J., Hsu, K. C., Hsu, J. Y., Lin, T. E. & Yang, C. R., 2025, 於: International Journal of Biological Sciences. 21, 2, p. 685-707 23 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., 6月 2024, 於: Protein Science. 33, 6, e5007.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取2 引文 斯高帕斯(Scopus)
資料集
-
Additional file 1: of Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Yeh, Y.-L. (Creator), Wang, Y.-J. (Contributor), Chiu, H.-W. (Creator), Ho, S.-Y. (Contributor), Wang, Y.-C. (Contributor), Lin, P. (Contributor) & Huang, W.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276_d1.v1
資料集: Dataset
-
Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Chiu, H.-W. (Creator), Yeh, Y.-L. (Creator), Wang, Y.-C. (Contributor), Huang, W.-J. (Contributor), Ho, S.-Y. (Contributor), Lin, P. (Contributor) & Wang, Y.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276.v1
資料集: Dataset
-
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
資料集: Dataset