Wei-Jan Huang

查看斯高帕斯 (Scopus) 概要

電子郵件wjhuangtmu.edutw

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每年研究成果

學歷

2002 臺灣大學藥學研究所博士
1995 臺灣大學藥學研究所碩士
1992 臺北醫學大學藥學系學士

經歷

2019.11- 臺北醫學大學藥物科學學科教授
2019.08- 臺北醫學大學藥物科學學科主任
2017.08- 臺北醫學大學藥學院生藥學研究所教授
2013.08- 臺北醫學大學中草藥臨床藥物研發博士學位學程
2011.08-2017.07 臺北醫學大學藥學院生藥學研究所副教授
2007.08-2011.07 臺北醫學大學藥學院生藥學研究所助理教授
2004.08-2007.07 長庚科技大學助理教授
2003.09-2004.07 清華大學化學系博士後研究
2002.08-2003.08 臺大醫學院藥物研究中心博士後研究

研究興趣

天然物化學
有機合成
藥物化學

指紋

查看啟用 Wei-Jan Huang 的研究主題。這些主題標籤來自此人的作品。共同形成了獨特的指紋。

1 類似的個人檔案

1 使用中
20 已完成

設計與合成新穎週期蛋白依賴性激酶8（CDK8）抑制劑作為具治療特發性肺纖維化潛力先導化合物(1/3)
Huang, W.-J. (PI)
8/1/24 → 7/31/25
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
探索新穎可逆性蛋白質雙硫鍵異構酶抑制劑
Huang, W.-J. (PI)
7/1/24 → 2/28/25
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(3/3)
Huang, W.-J. (PI)
8/1/23 → 7/31/24
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(2/3)
Huang, W.-J. (PI)
8/1/22 → 7/31/23
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(1/3)
Huang, W.-J. (PI)
8/1/21 → 7/31/22
研究計畫: A - 政府部門 › b - 國家科學及技術委員會

113 文章
1 回顧型文獻

CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcinoma
Lee, K. L., Liu, J. J., Huang, W. J., Hung, C. S. & Liang, Y. C., 12月 2025, 於: Cancer Cell International. 25, 1, 56.
研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取
Discovery and biological evaluation of potent 2-trifluoromethyl acrylamide warhead-containing inhibitors of protein disulfide isomerase
Chu, J. C., Tsai, K. C., Wang, T. Y., Chen, T. Y., Tsai, J. Y., Lee, T., Lin, M. H., Hsieh, Y. S. Y., Wu, C. C. & Huang, W. J., 2月 5 2025, 於: European Journal of Medicinal Chemistry. 283, p. 117169 117169.
研究成果: 雜誌貢獻 › 文章 › 同行評審
1 引文斯高帕斯（Scopus）
Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening
Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., 1月 13 2025, 於: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.
研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取
The Cyclin-Dependent Kinase 8 Inhibitor E966–0530–45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo
Chou, C. H., Huang, W. J., Hsu, K. C., Hsu, J. Y., Lin, T. E. & Yang, C. R., 2025, 於: International Journal of Biological Sciences. 21, 2, p. 685-707 23 p.
研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., 6月 2024, 於: Protein Science. 33, 6, e5007.
研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取
2 引文斯高帕斯（Scopus）

Additional file 1: of Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Yeh, Y.-L. (Creator), Wang, Y.-J. (Contributor), Chiu, H.-W. (Creator), Ho, S.-Y. (Contributor), Wang, Y.-C. (Contributor), Lin, P. (Contributor) & Huang, W.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276_d1.v1
資料集: Dataset
Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Chiu, H.-W. (Creator), Yeh, Y.-L. (Creator), Wang, Y.-C. (Contributor), Huang, W.-J. (Contributor), Ho, S.-Y. (Contributor), Lin, P. (Contributor) & Wang, Y.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276.v1
資料集: Dataset
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
資料集: Dataset

黃偉展

個人檔案

學歷

經歷

研究興趣

指紋

過去五年中的合作和熱門研究領域

深入探索詳細資料

設計與合成新穎週期蛋白依賴性激酶8（CDK8）抑制劑作為具治療特發性肺纖維化潛力先導化合物(1/3)

探索新穎可逆性蛋白質雙硫鍵異構酶抑制劑

結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(3/3)

結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(2/3)

結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(1/3)

CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcinoma

Discovery and biological evaluation of potent 2-trifluoromethyl acrylamide warhead-containing inhibitors of protein disulfide isomerase

Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening

The Cyclin-Dependent Kinase 8 Inhibitor E966–0530–45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo

An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors

Additional file 1: of Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model

Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model

Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

黃 偉展

個人檔案

學歷

經歷

研究興趣

指紋

過去五年中的合作和熱門研究領域

專案

研究成果

資料集

黃偉展