Shiow-Lin Pan

2009

EPOX inhibits angiogenesis by degradation of Mcl-1 through ERK inactivation

Sun, H. L., Tsai, A. C., Pan, S. L., Ding, Q., Yamaguchi, H., Lin, C. N., Hung, M. C. & Teng, C. M., 8月 1 2009, 於: Clinical Cancer Research. 15, 15, p. 4904-4914 11 p.

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21 引文斯高帕斯（Scopus）

Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1α accumulation in RAW264.7

Liu, Y. N., Pan, S. L., Liao, C. H., Huang, D. Y., Guh, J. H., Peng, C. Y., Chang, Y. L. & Teng, C. M., 9月 2009, 於: Shock. 32, 3, p. 263-269 7 p.

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60 引文斯高帕斯（Scopus）

2010

Antitumor agents. 272. Structure-activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues

Dong, Y., Shi, Q., Pai, H. C., Peng, C. Y., Pan, S. L., Teng, C. M., Nakagawa-Goto, K., Yu, D., Liu, Y. N., Wu, P. C., Bastow, K. F., Morris-Natschke, S. L., Brossi, A., Lang, J. Y., Hsu, J. L., Hung, M. C., Lee, E. Y. H. P. & Lee, K. H., 3月 11 2010, 於: Journal of Medicinal Chemistry. 53, 5, p. 2299-2308 10 p.

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60 引文斯高帕斯（Scopus）

Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways

Chiang, P. C., Lin, S. C., Pan, S. L., Kuo, C. H., Tsai, I. L., Kuo, M. T., Wen, W. C., Chen, P. & Guh, J. H., 1月 15 2010, 於: Biochemical Pharmacology. 79, 2, p. 162-171 10 p.

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110 引文斯高帕斯（Scopus）

CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation

Tsai, A. C., Pan, S. L., Sun, H. L., Wang, C. Y., Peng, C. Y., Wang, S. W., Chang, Y. L., Kuo, S. C., Lee, K. H. & Teng, C. M., 2月 19 2010, 於: Journal of Biological Chemistry. 285, 8, p. 5497-5506 10 p.

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27 引文斯高帕斯（Scopus）

Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo

Tsai, A. C., Pan, S. L., Liao, C. H., Guh, J. H., Wang, S. W., Sun, H. L., Liu, Y. N., Chen, C. C., Shen, C. C., Chang, Y. L. & Teng, C. M., 6月 2010, 於: Cancer Letters. 292, 2, p. 163-170 8 p.

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48 引文斯高帕斯（Scopus）

Moscatilin repressed lipopolysaccharide-induced hif-1α accumulation and NF-κB activation in murine raw264.7 cells

Liu, Y. N., Pan, S. L., Peng, C. Y., Huang, D. Y., Guh, J. H., Chen, C. C., Shen, C. C. & Teng, C. M., 1月 2010, 於: Shock. 33, 1, p. 70-75 6 p.

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28 引文斯高帕斯（Scopus）

The indazole derivative YD-3 specifically inhibits thrombin-induced angiogenesis in vitro and in vivo

Peng, C. Y., Pan, S. L., Pai, H. C., Tsai, A. C., Guh, J. H., Chang, Y. L., Kuo, S. C., Lee, F. Y. & Teng, C. M., 12月 2010, 於: Shock. 34, 6, p. 580-585 6 p.

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5 引文斯高帕斯（Scopus）

2011

Antitumor activity of a novel histone deacetylase inhibitor (S)-HDAC42 in oral squamous cell carcinoma

Bai, L. Y., Chiu, C. F., Pan, S. L., Sargeant, A. M., Shieh, T. M., Wang, Y. C. & Weng, J. R., 12月 2011, 於: Oral Oncology. 47, 12, p. 1127-1133 7 p.

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9 引文斯高帕斯（Scopus）

Antitumor agents 288: Design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents

Yang, X., Shi, Q., Yang, S. C., Chen, C. Y., Yu, S. L., Bastow, K. F., Morris-Natschke, S. L., Wu, P. C., Lai, C. Y., Wu, T. S., Pan, S. L., Teng, C. M., Lin, J. C., Yang, P. C. & Lee, K. H., 7月 28 2011, 於: Journal of Medicinal Chemistry. 54, 14, p. 5097-5107 11 p.

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35 引文斯高帕斯（Scopus）

Costunolide induces apoptosis through nuclear calcium²⁺ overload and DNA damage response in human prostate cancer

Hsu, J. L., Pan, S. L., Ho, Y. F., Hwang, T. L., Kung, F. L. & Guh, J. H., 5月 2011, 於: Journal of Urology. 185, 5, p. 1967-1974 8 p.

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45 引文斯高帕斯（Scopus）

The inhibition of angiogenesis and tumor growth by denbinobin is associated with the blocking of insulin-like growth factor-1 receptor signaling

Tsai, A. C., Pan, S. L., Lai, C. Y., Wang, C. Y., Chen, C. C., Shen, C. C. & Teng, C. M., 7月 2011, 於: Journal of Nutritional Biochemistry. 22, 7, p. 625-633 9 p.

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8 引文斯高帕斯（Scopus）

Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1α translational pathway in colorectal cancer cells

Chang, L. H., Chen, C-H., Huang, D. Y., Pai, H. C., Pan, S. L. & Teng, C. M., 4月 2011, 於: Journal of Cellular Physiology. 226, 4, p. 1060-1068 9 p.

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29 引文斯高帕斯（Scopus）

2012

Aciculatin induces p53-dependent apoptosis via MDM2 depletion in human cancer cells in vitro and in vivo

Lai, C. Y., Tsai, A. C., Chen, M. C., Chang, L. H., Sun, H. L., Chang, Y. L., Chen, C. C., Teng, C. M. & Pan, S. L., 8月 13 2012, 於: PLoS One. 7, 8, e42192.

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30 引文斯高帕斯（Scopus）

Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo

Huang, H-L., Lee, H. Y., Tsai, A-C., Peng, C-Y., Lai, M-J., Wang, J-C., Pan, S. L., Teng, C-M. & Liou, J. P., 8月 22 2012, 於: PLoS ONE. 7, 8, e43645.

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31 引文斯高帕斯（Scopus）

Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: Design, synthesis, and mechanistic studies

Yang, X., Shi, Q., Lai, C. Y., Chen, C. Y., Ohkoshi, E., Yang, S. C., Wang, C. Y., Bastow, K. F., Wu, T. S., Pan, S. L., Teng, C. M., Yang, P. C. & Lee, K. H., 8月 9 2012, 於: Journal of Medicinal Chemistry. 55, 15, p. 6751-6761 11 p.

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23 引文斯高帕斯（Scopus）

Chrysin restores PDGF-induced inhibition on protein tyrosine phosphatase and reduces PDGF signaling in cultured VSMCs

Lo, H. M., Wu, M. W., Pan, S. L., Peng, C. Y., Wu, P. H. & Wu, W. B., 6月 2012, 於: Journal of Nutritional Biochemistry. 23, 6, p. 667-678 12 p.

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22 引文斯高帕斯（Scopus）

Dehydrocostuslactone suppresses angiogenesis in vitro and in vivo through inhibition of AKT/GSK-3β and mtor signaling pathways

Wang, C. Y., Tsai, A. C., Peng, C. Y., Chang, Y. L., Lee, K. H., Teng, C. M. & Pan, S. L., 2月 16 2012, 於: PLoS ONE. 7, 2, e31195.

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45 引文斯高帕斯（Scopus）

DYZ-2-90, a Novel Neo-tanshinlactone Ring-Opened Compound, Induces ERK-Mediated Mitotic Arrest and Subsequent Apoptosis by Activating JNK in Human Colorectal Cancer Cells

Wang, L. T., Pan, S. L., Chen, T. H., Dong, Y., Lee, K. H. & Teng, C. M., 7月 23 2012, 於: ChemBioChem. 13, 11, p. 1663-1672 10 p.

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7 引文斯高帕斯（Scopus）

Physalin F induces cell apoptosis in human renal carcinoma cells by targeting NF-kappaB and generating reactive oxygen species

Wu, S. Y., Leu, Y. L., Chang, Y. L., Wu, T. S., Kuo, P. C., Liao, Y. R., Teng, C. M. & Pan, S. L., 7月 16 2012, 於: PLoS ONE. 7, 7, e40727.

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53 引文斯高帕斯（Scopus）

Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines

Chen, C-H., Liao, C. H., Chang, Y. L., Guh, J. H., Pan, S. L. & Teng, C. M., 2月 1 2012, 於: Cancer Letters. 315, 1, p. 1-11 11 p.

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49 引文斯高帕斯（Scopus）

QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells

Chen, M. C., Pan, S. L., Shi, Q., Xiao, Z., Lee, K. H., Li, T. K. & Teng, C. M., 1月 2012, 於: Cancer Science. 103, 1, p. 80-87 8 p.

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13 引文斯高帕斯（Scopus）

Synthesis and biological evaluation of 1-arylsulfonyl-5-(N -hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo

Lai, M. J., Huang, H. L., Pan, S. L., Liu, Y. M., Peng, C. Y., Lee, H. Y., Yeh, T. K., Huang, P. H., Teng, C. M., Chen, C. S., Chuang, H. Y. & Liou, J. P., 4月 26 2012, 於: Journal of Medicinal Chemistry. 55, 8, p. 3777-3791 15 p.

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59 引文斯高帕斯（Scopus）

α-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways

Chao, M. W., Chen, C-H., Chang, Y. L., Teng, C. M. & Pan, S. L., 9月 6 2012, 於: PLoS One. 7, 9, e44093.

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29 引文斯高帕斯（Scopus）

2013

Activated PAR-2 regulates pancreatic cancer progression through ILK/HIF-α-induced TGF-α expression and MEK/VEGF-a-mediated angiogenesis

Chang, L. H., Pan, S. L., Lai, C. Y., Tsai, A. C. & Teng, C. M., 8月 2013, 於: American Journal of Pathology. 183, 2, p. 566-575 10 p.

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39 引文斯高帕斯（Scopus）

Azatyrosinamides: Novel RAS-related anticancer agents

Wang, C. L., Lee, O., Huang, C. F., Li, E. I. C., Teng, C. M., Pan, S. L., Lian, J. F., Chang, F. S., Liou, J. P. & Wang, H. P., 2月 2013, 於: Anticancer Research. 33, 2, p. 425-432 8 p.

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2 引文斯高帕斯（Scopus）

Denbinobin induces human glioblastoma multiforme cell apoptosis through the IKKα-Akt-FKHR signaling cascade

Weng, H. Y., Hsu, M. J., Chen, C. C., Chen, B. C., Hong, C. Y., Teng, C. M., Pan, S. L., Chiu, W. T. & Lin, C. H., 1月 5 2013, 於: European Journal of Pharmacology. 698, 1-3, p. 103-109 7 p.

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11 引文斯高帕斯（Scopus）

Depletion of 4E-BP1 and regulation of autophagy lead to YXM110-induced anticancer effects

Lai, C. Y., Pan, S. L., Yang, X. M., Chang, L. H., Chang, Y. L., Yang, P. C., Lee, K. H. & Teng, C. M., 9月 2013, 於: Carcinogenesis. 34, 9, p. 2050-2060 11 p.

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8 引文斯高帕斯（Scopus）

Furanylazaindoles: Potent anticancer agents in vitro and in vivo

Lee, H. Y., Pan, S. L., Su, M-C., Liu, Y-M., Kuo, C-C., Chang, Y-T., Wu, J-S., Nien, C-Y., Mehndiratta, S., Chang, C-Y., Wu, S-Y., Lai, M-J., Chang, J-Y. & Liou, J. P., 2013, 於: Journal of Medicinal Chemistry. 56, 20, p. 8008-8018 11 p.

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46 引文斯高帕斯（Scopus）

Moscatilin inhibits migration and metastasis of human breast cancer MDA-MB-231 cells through inhibition of Akt and Twist signaling pathway

Pai, H. C., Chang, L. H., Peng, C. Y., Chang, Y. L., Chen, C. C., Shen, C. C., Teng, C. M. & Pan, S. L., 3月 2013, 於: Journal of Molecular Medicine. 91, 3, p. 347-356 10 p.

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43 引文斯高帕斯（Scopus）

The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells

Chen, M. C., Chen, C. H., Wang, J. C., Tsai, A. C., Liou, J. P., Pan, S. L. & Teng, C. M., 9月 2013, 於: Cell Death and Disease. 4, 9, e810.

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65 引文斯高帕斯（Scopus）

TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells

Chen, M. C., Chen, C. H., Liu, Y. N., Wang, H. P., Pan, S. L. & Teng, C. M., 8月 19 2013, 於: Cancer Letters. 336, 2, p. 370-378 9 p.

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15 引文斯高帕斯（Scopus）

2014

A novel action mechanism for MPT0g013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through upregulation of TIMP3 expression

Wang, C-Y., Liou, J. P., Tsai, A-C., Lai, M-J., Liu, Y-M., Lee, H. Y., Wang, J-C., Pan, S. L. & Teng, C-M., 2014, 於: Oncotarget. 5, 20, p. 9838-9850 13 p.

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10 引文斯高帕斯（Scopus）

A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCδ and E-cadherin

Wang, L. T., Liou, J. P., Li, Y. H., Liu, Y. M., Pan, S. L. & Teng, C. M., 2014, 於: Oncotarget. 5, 14, p. 5651-5662 12 p.

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31 引文斯高帕斯（Scopus）

A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i

Yu, C. C., Pan, S. L., Chao, S. W., Liu, S. P., Hsu, J. L., Yang, Y. C., Li, T. K., Huang, W. J. & Guh, J. H., 8月 1 2014, 於: Biochemical Pharmacology. 90, 3, p. 320-330 11 p.

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27 引文斯高帕斯（Scopus）

Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Lee, H. Y., Tsai, A. C., Chen, M. C., Shen, P. J., Cheng, Y. C., Kuo, C. C., Pan, S. L., Liu, Y. M., Liu, J. F., Yeh, T. K., Wang, J. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 5月 22 2014, 於: Journal of Medicinal Chemistry. 57, 10, p. 4009-4022 14 p.

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62 引文斯高帕斯（Scopus）

Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents

Wang, M. J., Liu, Y. Q., Chang, L. C., Wang, C. Y., Zhao, Y. L., Zhao, X. B., Qian, K., Nan, X., Yang, L., Yang, X. M., Hung, H. Y., Yang, J. S., Kuo, D. H., Goto, M., Morris-Natschke, S. L., Pan, S. L., Teng, C. M., Kuo, S. C., Wu, T. S., Wu, Y. C., 及其他1Lee, K. H., 7月 24 2014, 於: Journal of Medicinal Chemistry. 57, 14, p. 6008-6018 11 p.

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63 引文斯高帕斯（Scopus）

Effect of C7-substitution of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines on the selectivity towards a subclass of histone deacetylases

Lee, H. Y., Wang, L. T., Li, Y. H., Pan, S. L., Chen, Y. L., Teng, C. M. & Liou, J. P., 11月 28 2014, 於: Organic and Biomolecular Chemistry. 12, 44, p. 8966-8976 11 p.

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7 引文斯高帕斯（Scopus）

In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells

Tsai, A. C., Pai, H. C., Wang, C. Y., Liou, J. P., Teng, C. M., Wang, J. C. & Pan, S. L., 1月 2014, 於: British Journal of Pharmacology. 171, 1, p. 122-133 12 p.

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8 引文斯高帕斯（Scopus）

Moniliformediquinone induces in vitro and in vivo antitumor activity through glutathione involved DNA damage response and mitochondrial stress in human hormone refractory prostate cancer

Hsu, J. L., Lee, Y. J., Leu, W. J., Dong, Y. S., Pan, S. L., Uang, B. J. & Guh, J. H., 2014, 於: Journal of Urology. 191, 5, p. 1429-1438 10 p.

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12 引文斯高帕斯（Scopus）

NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells

Wu, S. Y., Pan, S. L., Xiao, Z. Y., Hsu, J. L., Chen, M. C., Lee, K. H. & Teng, C. M., 11月 5 2014, 於: PLoS ONE. 9, 11, e112220.

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13 引文斯高帕斯（Scopus）

Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib

Tsai, A. C., Wang, C. Y., Liou, J. P., Pai, H. C., Hsiao, C. J., Chang, J. Y., Wang, J. C., Teng, C. M. & Pan, S. L., 4月 2014, 於: Cell Death and Disease. 5, 4, e1162.

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17 引文斯高帕斯（Scopus）

Radiation-induced VEGF-C expression and endothelial cell proliferation in lung cancer

Chen, Y. H., Pan, S. L., Wang, J. C., Kuo, S. H., Cheng, J. C. H. & Teng, C. M., 11月 22 2014, 於: Strahlentherapie und Onkologie. 190, 12, p. 1154-1162 9 p.

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29 引文斯高帕斯（Scopus）

Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo

Chen, C. H., Chen, M. C., Wang, J. C., Tsai, A. C., Chen, C. S., Liou, J. P., Pan, S. L. & Teng, C. M., 2014, 於: Clinical Cancer Research. 20, 5, p. 1274-1287 14 p.

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43 引文斯高帕斯（Scopus）

2015

1-arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells

Liu, Y-M., Lee, H. Y., Chen, C-H., Lee, C-H., Wang, L-T., Pan, S. L., Lai, M-J., Yeh, T-K. & Liou, J. P., 1月 2015, 於: European Journal of Medicinal Chemistry. 89, p. 320-330 11 p.

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18 引文斯高帕斯（Scopus）

Dual Phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer

Chen, Y. H., Wei, M. F., Wang, C. W., Lee, H. W., Pan, S. L., Gao, M., Kuo, S. H., Cheng, A. L. & Teng, C. M., 2月 28 2015, 於: Cancer Letters. 357, 2, p. 582-590 9 p.

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37 引文斯高帕斯（Scopus）

eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer

Chao, M. W., Wang, L. T., Lai, C. Y., Yang, X. M., Cheng, Y. W., Lee, K. H., Pan, S. L. & Teng, C. M., 2015, 於: Oncotarget. 6, 27, p. 24092-24104 13 p.

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