每年專案
個人檔案
學歷
- 2002 臺大醫學院藥理學研究所博士
- 1994 臺北醫學大學醫學研究所碩士
經歷
- 2023.03- 臺北醫學大學醫學科技學院院長
- 2020-2023 臺北醫學大學醫學科技學院副院長
- 2019-2022 臺北醫學大學新藥研發產業博士學位學程主任
- 2018- 臺北醫學大學癌症生物學與藥物研發研究所教授
- 2017- 臺北醫學大學生技醫療產業研發博士學位學程教授
- 2016-2018 臺北醫學大學癌症生物學與藥物研發博士學位學程教授
- 2013-2016 臺北醫學大學癌症生物學與藥物研發博士學位學程副教授
- 2008-2013 臺北醫學大學藥理學科助理教授
- 2009-2013 國家衛生研究院助理研究員
- 2007-2009 臺大醫學院助研究員
- 2002-2007 臺大醫學院博士後研究
- 1994-1998 長庚大學醫學系助教
獎項
- 2019 臺北醫學大學單一研究計畫經費獎
研究興趣
- 藥物研發
- 疾病動物模式
- 藥理藥效學
相關連結
指紋
- 1 類似的個人檔案
過去五年中的合作和熱門研究領域
專案
- 34 已完成
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研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究-探討 DYRK1/CLK 抑制劑於人類消化道癌進行 mRNA splicing 調控機制和治療潛力(1/3)
Pan, S.-L. (PI)
8/1/23 → 7/31/24
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., 6月 2024, 於: Protein Science. 33, 6, e5007.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
Correction to: The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells (Cell Death & Disease, (2013), 4, 9, (e810), 10.1038/cddis.2013.330)
Chen, M. C., Chen, C. H., Wang, J. C., Tsai, A. C., Liou, J. P., Pan, S. L. & Teng, C. M., 7月 2024, 於: Cell Death and Disease. 15, 7, 490.研究成果: 雜誌貢獻 › 評論/辯論 › 同行評審
開啟存取 -
Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule
Wu, Y. W., HuangFu, W. C., Lin, T. E., Peng, C. H., Tu, H. J., Sung, T. Y., Sung, T. Y., Yen, S. C., Pan, S. L. & Hsu, K. C., 2月 2024, 於: International Journal of Biological Macromolecules. 259, 129074.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取1 引文 斯高帕斯(Scopus) -
In silico identification of a novel Cdc2-like kinase 2 (CLK2) inhibitor in triple negative breast cancer
Huang, C. C., Hsu, C. M., Chao, M. W., Hsu, K. C., Lin, T. E., Yen, S. C., Tu, H. J. & Pan, S. L., 6月 2024, 於: Protein Science. 33, 6, e5004.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
Syntheses of LSD1/HDAC Inhibitors with Demonstrated Efficacy against Colorectal Cancer: In Vitro and In Vivo Studies Including Patient-Derived Organoids
Chou, P. Y., Lai, M. J., Tsai, K. K., Cheng, L. H., Wu, Y. W., Chen, M. C., Pan, S. L., Ho, H. O., Nepali, K. & Liou, J. P., 2024, (接受/付印) 於: Journal of Medicinal Chemistry. 67, 19, p. 17207-17225 19 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取
資料集
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Additional file 1 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody
Cheng, Y.-W. (Creator), Cheng, C.-C. (Creator), HuangFu, W.-C. (Creator), Pan, S.-L. (Creator), Sung, T.-Y. (Creator), Chang, F.-L. (Creator), Huang, H.-L. (Contributor), Huang, C.-C. (Contributor), Wei, P.-L. (Contributor) & Lee, Y.-C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.14228278.v1, https://doi.org/10.6084%2Fm9.figshare.14228278.v1
資料集: Dataset
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The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells
Tu, H.-J. (Contributor), Lin, Y.-J. (Contributor), Chao, M.-W. (Contributor), Sung, T.-Y. (Creator), Wu, Y.-W. (Creator), Chen, Y.-Y. (Creator), Lin, M.-H. (Contributor), Liou, J.-P. (Creator), Pan, S.-L. (Contributor) & Yang, C.-R. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4350887.v1, https://springernature.figshare.com/collections/The_anticancer_effects_of_MPT0G211_a_novel_HDAC6_inhibitor_combined_with_chemotherapeutic_agents_in_human_acute_leukemia_cells/4350887/1
資料集: Dataset
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Gene expression profiling of pancreatic cancer cell line BxPC-3 induced by PAR-2 AP
Chang, L.-H. (Contributor), Pan, S.-L. (Contributor), Lai, C.-Y. (Contributor), Tsai, A.-C. (Contributor) & Teng, C.-M. (Contributor), Gene Expression Omnibus, 2013
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE44827
資料集: Dataset
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Additional file 5: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chang, L.-H. (Contributor), Liou, J.-P. (Creator), Lai, M.-J. (Contributor), Chang, C.-D. (Contributor), Tu, H.-J. (Contributor), Chao, M.-W. (Contributor), Pan, S.-L. (Contributor), Chen, Y.-Y. (Creator) & Teng, C.-M. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8202902.v1, https://doi.org/10.6084%2Fm9.figshare.8202902.v1
資料集: Dataset
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Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C.-F. (Creator), Hsu, K.-C. (Creator), Huangfu, W.-C. (Contributor), Lin, T. E. (Creator), Huang, H.-L. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.c.4896705.v1, https://springernature.figshare.com/collections/Investigating_the_potential_effects_of_selective_histone_deacetylase_6_inhibitor_ACY1215_on_infarct_size_in_rats_with_cardiac_ischemia-reperfusion_injury/4896705/1
資料集: Dataset