Ming-Thau Sheu

2023

Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer

Liu, Y. H., Chen, L. C., Cheng, W. T., Wei, P. S., Hsieh, C. M., Sheu, M. T., Lin, S. Y., Ho, H. O. & Lin, H. L., 2月 2023, 於: Pharmaceutics. 15, 2, 473.

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2022

A novel anti-tumor/anti-tumor-associated fibroblast/anti-mPEG tri-specific antibody to maximize the efficacy of mPEGylated nanomedicines against fibroblast-rich solid tumor

Chen, M., Sheu, M. T., Cheng, T. L., Roffler, S. R., Lin, S. Y., Chen, Y. J., Cheng, Y. A., Cheng, J. J., Chang, H. Y., Wu, T. Y., Kao, A. P., Ho, Y. S. & Chuang, K. H., 1月 7 2022, 於: Biomaterials Science. 10, 1, p. 202-215 14 p.

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3 引文斯高帕斯（Scopus）

Bispecific T-cell engagers non-covalently decorated drug-loaded PEGylated nanocarriers for cancer immunochemotherapy

Cheng, W. J., Chuang, K. H., Lo, Y. J., Chen, M., Chen, Y. J., Roffler, S. R., Ho, H. O., Lin, S. Y. & Sheu, M. T., 4月 2022, 於: Journal of Controlled Release. 344, p. 235-248 14 p.

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4 引文斯高帕斯（Scopus）

Combined Docetaxel/Pictilisib-Loaded mPEGylated Nanocarriers with Dual HER2 Targeting Antibodies for Synergistic Chemotherapy of Breast Cancer

Cheng, W. J., Lin, S. Y., Chuang, K. H., Chen, M., Ho, H. O., Chen, L. C., Hsieh, C. M. & Sheu, M. T., 2022, 於: International Journal of Nanomedicine. 17, p. 5353-5374 22 p.

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Glycosylation of OVA antigen-loaded PLGA nanoparticles enhances DC-targeting for cancer vaccination

Chou, P. Y., Lin, S. Y., Wu, Y. N., Shen, C. Y., Sheu, M. T. & Ho, H. O., 11月 2022, 於: Journal of Controlled Release. 351, p. 970-988 19 p.

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5 引文斯高帕斯（Scopus）

Preclinical Therapeutic Assessment of a New Chemotherapeutics [Dichloro(4,4’-Bis(2,2,3,3-Tetrafluoropropoxy) Methyl)-2,2’-Bipryridine) Platinum] in an Orthotopic Patient-Derived Xenograft Model of Triple-Negative Breast Cancers

Kan, T. C., Lin, M. H., Cheng, C. C., Lu, J. W., Sheu, M. T., Ho, Y. S., Rahayu, S. & Chang, J., 4月 2022, 於: Pharmaceutics. 14, 4, 839.

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1 引文斯高帕斯（Scopus）

2021

Active Tumoral/Tumor Environmental Dual-Targeting by Non-Covalently Arming with Trispecific Antibodies or Dual-Bispecific Antibodies on Docetaxel-Loaded mPEGylated Nanocarriers to Enhance Chemotherapeutic Efficacy and Minimize Systemic Toxicity

Cheng, W. J., Lin, S. Y., Chen, M., Chen, L. C., Ho, H. O., Chuang, K. H. & Sheu, M. T., 2021, 於: International Journal of Nanomedicine. 16, p. 4017-4030 14 p.

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4 引文斯高帕斯（Scopus）

Carfilzomib and paclitaxel co-loaded protein nanoparticles an effective therapy against pancreatic adenocarcinomas

Cheng, W. T., Ho, H. O., Lin, S. Y., Liu, D. Z., Chen, L. C. & Sheu, M. T., 10月 2021, 於: International Journal of Nanomedicine. 16, p. 6825-6841 17 p.

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6 引文斯高帕斯（Scopus）

CPT11 with P-glycoprotein/CYP 3A4 dual-function inhibitor by self-nanoemulsifying nanoemulsion combined with gastroretentive technology to enhance the oral bioavailability and therapeutic efficacy against pancreatic adenocarcinomas

Chen, L. C., Cheng, W. J., Lin, S. Y., Hung, M. T., Sheu, M. T., Lin, H. L. & Hsieh, C. M., 2021, 於: Drug Delivery. 28, 1, p. 2205-2217 13 p.

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3 引文斯高帕斯（Scopus）

Fabrication and characterization of Rhizochitosan and its incorporation with platelet concentrates to promote wound healing

Chen, L. C., Lin, S. Y., Sheu, M. T., Su, C. H., Lin, H. L. & Hsieh, C. M., 9月 15 2021, 於: Carbohydrate Polymers. 268, p. 118239 118239.

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6 引文斯高帕斯（Scopus）

In situ subcutaneously injectable thermosensitive PEG-PLGA diblock and PLGA-PEG-PLGA triblock copolymer composite as sustained delivery of bispecific anti-CD3 scFv T-cell/anti-EGFR Fab Engager (BiTEE)

Wei, P. S., Chen, Y. J., Lin, S. Y., Chuang, K. H., Sheu, M. T. & Ho, H. O., 11月 2021, 於: Biomaterials. 278, 121166.

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10 引文斯高帕斯（Scopus）

One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration

Wu, M. H., Wang, W., Chao, F. C., Hsieh, C. M., Chen, L. C., Lin, H. L., Ho, H. O., Huang, T. J. & Sheu, M. T., 2月 2021, 於: Carbohydrate Polymers. 254, 117270.

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2 引文斯高帕斯（Scopus）

Type-3 hyaluronan synthase attenuates tumor cells invasion in human mammary parenchymal tissues

Lee, W. J., Tu, S. H., Cheng, T. C., Lin, J. H., Sheu, M. T., Kuo, C. C., Changou, C. A., Wu, C. H., Chang, H. W., Chang, H. L., Chen, L. C. & Ho, Y. S., 11月 1 2021, 於: Molecules. 26, 21, 6548.

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1 引文斯高帕斯（Scopus）

2020

A novel composite hydrogel composed of formic acid-decellularized pepsin-soluble extracellular matrix hydrogel and sacchachitin hydrogel as wound dressing to synergistically accelerate diabetic wound healing

Hsieh, C. M., Wang, W., Chen, Y. H., Wei, P. S., Liu, Y. H., Sheu, M. T. & Ho, H. O., 6月 11 2020, 於: Pharmaceutics. 12, 6, p. 1-18 18 p., 538.

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17 引文斯高帕斯（Scopus）

Micronized sacchachitin promotes satellite cell proliferation through TAK1-JNK-AP-1 signaling pathway predominantly by TLR2 activation

Wu, M. H., Lin, C. Y., Hou, C. Y., Sheu, M. T. & Chang, H., 9月 22 2020, 於: Chinese Medicine (United Kingdom). 15, 1, 100.

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3 引文斯高帕斯（Scopus）

Preparation and characterization of a novel swellable and floating gastroretentive drug delivery system (sfGRDDS) for enhanced oral bioavailability of nilotinib

Lin, H. L., Chen, L. C., Cheng, W. T., Cheng, W. J., Ho, H. O. & Sheu, M. T., 2月 2020, 於: Pharmaceutics. 12, 2, 137.

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14 引文斯高帕斯（Scopus）

Preparation and characterization of chemically TEMPO-oxidized and mechanically disintegrated sacchachitin nanofibers (SCNF) for enhanced diabetic wound healing

Chao, F. C., Wu, M. H., Chen, L. C., Lin, H. L., Liu, D. Z., Ho, H. O. & Sheu, M. T., 2月 1 2020, 於: Carbohydrate Polymers. 229, p. 115507 115507.

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20 引文斯高帕斯（Scopus）

TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) combined with platelet-rich plasma (PRP) for management of dry eye syndrome

Lin, H. L., Wu, T. H., Ho, H. O., Chao, F. C., Meng-Huang, Liu, W. D. Z., Chen, L. C. & Sheu, M. T., 1月 1 2020, 於: International Journal of Nanomedicine. 15, p. 1721-1730 10 p.

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4 引文斯高帕斯（Scopus）

The antihistamine deptropine induces hepatoma cell death through blocking autophagosome-lysosome fusion

Liang, Y. C., Chang, C. C., Sheu, M. T., Lin, S. Y., Chung, C. C., Teng, C. T. & Suk, F. M., 6月 2020, 於: Cancers. 12, 6, p. 1-14 14 p., 1610.

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9 引文斯高帕斯（Scopus）

2019

Development of Decellularized Cornea by Organic Acid Treatment for Corneal Regeneration

Lin, H. J., Wang, T. J., Li, T. W., Chang, Y. Y., Sheu, M. T., Huang, Y. Y. & Liu, D. Z., 4月 1 2019, 於: Tissue Engineering - Part A. 25, 7-8, p. 652-662 11 p.

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16 引文斯高帕斯（Scopus）

In situ chemically crosslinked injectable hydrogels for the subcutaneous delivery of trastuzumab to treat breast cancer

Lo, Y. W., Sheu, M. T., Chiang, W. H., Chiu, Y. L., Tu, C. M., Wang, W. Y., Wu, M. H., Wang, Y. C., Lu, M. & Ho, H. O., 3月 1 2019, 於: Acta Biomaterialia. 86, p. 280-290 11 p.

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25 引文斯高帕斯（Scopus）

2018

Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors

Su, C. Y., Chen, M., Chen, L. C., Ho, Y. S., Ho, H. O., Lin, S. Y., Chuang, K. H. & Sheu, M. T., 11月 1 2018, 於: Drug Delivery. 25, 1, p. 1066-1079 14 p.

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19 引文斯高帕斯（Scopus）

Complex Hydrogels Composed of Chitosan with Ring-opened Polyvinyl Pyrrolidone as a Gastroretentive Drug Dosage Form to Enhance the Bioavailability of Bisphosphonates

Su, C-Y., Ho, H-O., Chen, Y-C., Yu, Y-T., Liu, D-Z., Chao, F-C. & Sheu, M-T., 5月 25 2018, 於: Scientific Reports. 8, 1, p. 8092

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19 引文斯高帕斯（Scopus）

Development and characterization of docetaxel-loaded lecithin-stabilized micellar drug delivery system (L_sbMDDs) for improving the therapeutic efficacy and reducing systemic toxicity

Su, C. Y., Liu, J. J., Ho, Y. S., Huang, Y. Y., Chang, V. H. S., Liu, D. Z., Chen, L. C., Ho, H. O. & Sheu, M. T., 2月 1 2018, 於: European Journal of Pharmaceutics and Biopharmaceutics. 123, p. 9-19 11 p.

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25 引文斯高帕斯（Scopus）

Lecithin-Stabilized Polymeric Micelles (LsbPMs) for Delivering Quercetin: Pharmacokinetic Studies and Therapeutic Effects of Quercetin Alone and in Combination with Doxorubicin

Chang, C-E., Hsieh, C-M., Huang, S-C., Su, C-Y., Sheu, M-T. & Ho, H-O., 12月 1 2018, 於: Scientific Reports. 8, 1, p. 17640 17640.

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13 引文斯高帕斯（Scopus）

Measurement of solid solubility of warfarin in supercritical carbon dioxide and recrystallization study using supercritical antisolvent process

Ciou, J. M., Wang, B. C., Su, C. S., Liu, J. J. & Sheu, M. T., 3月 2018, 於: Advanced Powder Technology. 29, 3, p. 479-487 9 p.

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14 引文斯高帕斯（Scopus）

Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

Chang, C. E., Hsieh, C. M., Chen, L. C., Su, C. Y., Liu, D. Z., Jhan, H. J., Ho, H. O. & Sheu, M. T., 1月 1 2018, 於: Drug Delivery. 25, 1, p. 632-643 12 p.

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20 引文斯高帕斯（Scopus）

Stearyl polyethylenimine complexed with plasmids as the core of human serum albumin nanoparticles noncovalently bound to CRISPR/Cas9 plasmids or siRNA for disrupting or silencing PD-L1 expression for immunotherapy

Cheng, W. J., Chen, L. C., Ho, H. O., Lin, H. L. & Sheu, M. T., 1月 1 2018, 於: International Journal of Nanomedicine. 13, p. 7079-7094 16 p.

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40 引文斯高帕斯（Scopus）

2017

Application of two-level factorial design to investigate the effect of process parameters on the sonocrystallization of sulfathiazole

Kuo, P. H., Zhang, B. C., Su, C. S., Liu, J. J. & Sheu, M. T., 8月 1 2017, 於: Journal of Crystal Growth. 471, p. 8-14 7 p.

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8 引文斯高帕斯（Scopus）

Determination of total and unbound docetaxel in plasma by ultrafiltration and UPLC-MS/MS: Application to pharmacokinetic studies

Sheu, M. T., Wu, C. Y., Su, C. Y. & Ho, H. O., 12月 1 2017, 於: Scientific Reports. 7, 1, 14609.

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4 引文斯高帕斯（Scopus）

Physical and Pharmacokinetic Characterizations of trans-Resveratrol (t-Rev) Encapsulated with Self-Assembling Lecithin-based Mixed Polymeric Micelles (saLMPMs)

Li, T. P., Wong, W. P., Chen, L. C., Su, C. Y., Chen, L. G., Liu, D. Z., Ho, H. O. & Sheu, M. T., 12月 1 2017, 於: Scientific Reports. 7, 1, 10674.

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15 引文斯高帕斯（Scopus）

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for in Vivo Gene Silencing in Leukemia

Lee, D. J., Kessel, E., Lehto, T., Liu, X., Yoshinaga, N., Padari, K., Chen, Y. C., Kempter, S., Uchida, S., Rädler, J. O., Pooga, M., Sheu, M. T., Kataoka, K. & Wagner, E., 9月 20 2017, 於: Bioconjugate Chemistry. 28, 9, p. 2393-2409 17 p.

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39 引文斯高帕斯（Scopus）

2016

Codelivery of doxorubicin-containing thermosensitive hydrogels incorporated with docetaxel-loaded mixed micelles enhances local cancer therapy

Sheu, M. T., Jhan, H. J., Su, C. Y., Chen, L. C., Chang, C. E., Liu, D. Z. & Ho, H. O., 7月 1 2016, 於: Colloids and Surfaces B: Biointerfaces. 143, p. 260-270 11 p.

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52 引文斯高帕斯（Scopus）

Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin

Chen, L. C., Chen, Y-C., Su, C. Y., Wong, W. P., Sheu, M-T. & Ho, H-O., 11月 16 2016, 於: Scientific Reports. 6, 37122.

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35 引文斯高帕斯（Scopus）

Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study

Chen, L. C., Chen, Y. C., Su, C. Y., Hong, C. S., Ho, H. O. & Sheu, M. T., 4月 15 2016, 於: International Journal of Nanomedicine. 11, p. 1557-1566 10 p.

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47 引文斯高帕斯（Scopus）

Improving the stability of astaxanthin by microencapsulation in calcium alginate beads

Lin, S. F., Chen, Y. C., Chen, R. N., Chen, L. C., Ho, H. O., Tsung, Y. H., Sheu, M. T. & Liu, D. Z., 4月 1 2016, 於: PLoS One. 11, 4, e0153685.

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43 引文斯高帕斯（Scopus）

Optimization of platelet-rich plasma and its effects on the recovery of erectile function after bilateral cavernous nerve injury in a rat model

Wu, Y. N., Wu, C. C., Sheu, M. T., Chen, K. C., Ho, H. O. & Chiang, H. S., 10月 1 2016, 於: Journal of Tissue Engineering and Regenerative Medicine. 10, 10, p. E294-E304

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55 引文斯高帕斯（Scopus）

Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo Pharmacokinetic Studies in Rabbits

Sheu, M. T., Hsieh, C. M., Chen, R. N., Chou, P. Y. & Ho, H. O., 9月 1 2016, 於: Journal of Pharmaceutical Sciences. 105, 9, p. 2774-2781 8 p.

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16 引文斯高帕斯（Scopus）

2015

Development and Characterization of Acellular Extracellular Matrix Scaffolds from Porcine Menisci for Use in Cartilage Tissue Engineering

Chen, Y. C., Chen, R. N., Jhan, H. J., Liu, D. Z., Ho, H. O., Mao, Y., Kohn, J. & Sheu, M. T., 9月 1 2015, 於: Tissue Engineering - Part C: Methods. 21, 9, p. 971-986 16 p.

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70 引文斯高帕斯（Scopus）

Efficacy of antioxidants as a complementary and alternative medicine (CAM) in combination with the chemotherapeutic agent doxorubicin

Sheu, M. T., Jhan, H. J., Hsieh, C. M., Wang, C. J. & Ho, H. O., 3月 17 2015, 於: Integrative Cancer Therapies. 14, 2, p. 184-195 12 p.

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35 引文斯高帕斯（Scopus）

Formulation and process optimization of multiparticulate pulsatile system delivered by osmotic pressure-activated rupturable membrane

Hung, S. F., Hsieh, C. M., Chen, Y. C., Lin, C. M., Ho, H. O. & Sheu, M. T., 3月 1 2015, 於: International Journal of Pharmaceutics. 480, 1-2, p. 15-26 12 p.

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11 引文斯高帕斯（Scopus）

Mycelial mattress from a sporangia formation-delayed mutant of Rhizopus stoloniferas wound healing-enhancing biomaterial

Chien, M. Y., Chen, L. C., Chen, Y. C., Sheu, M. T., Tsai, Y. C., Ho, H. O., Su, C. H. & Liu, D. Z., 8月 14 2015, 於: PLoS ONE. 10, 8, e0134090.

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5 引文斯高帕斯（Scopus）

Novel injectable thermosensitive hydrogels for delivering hyaluronic acid-doxorubicin nanocomplexes to locally treat tumors

Jhan, H. J., Liu, J. J., Chen, Y. C., Liu, D. Z., Sheu, M. T. & Ho, H. O., 4月 1 2015, 於: Nanomedicine. 10, 8, p. 1263-1274 12 p.

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29 引文斯高帕斯（Scopus）

Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles

Chen, Y. C., Su, C. Y., Jhan, H. J., Ho, H. O. & Sheu, M. T., 12月 2 2015, 於: International Journal of Nanomedicine. 10, p. 7265-7274 10 p.

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32 引文斯高帕斯（Scopus）

Solid-state property modification and dissolution rate enhancement of tolfenamic acid by supercritical antisolvent process

Chen, H. H., Su, C. S., Liu, J. J. & Sheu, M. T., 2015, 於: Journal of Supercritical Fluids. 101, p. 17-23 7 p.

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16 引文斯高帕斯（Scopus）

Swelling/floating capability and drug release characterizations of gastroretentive drug delivery system based on a combination of hydroxyethyl cellulose and sodium carboxymethyl cellulose

Chen, Y. C., Ho, H. O., Liu, D. Z., Siow, W. S. & Sheu, M. T., 1月 24 2015, 於: PLoS ONE. 10, 1, e0116914.

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41 引文斯高帕斯（Scopus）

2014

Biodistribution profiling of the chemical modified hyaluronic acid derivatives used for oral delivery system

Hsieh, C. M., Huang, Y. W., Sheu, M. T. & Ho, H. O., 2014, 於: International Journal of Biological Macromolecules. 64, p. 45-52 8 p.

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17 引文斯高帕斯（Scopus）

Characterizations of plasticized polymeric film coatings for preparing multiple-unit floating drug delivery systems (muFDDSs) with controlled-release characteristics

Hung, S. F., Hsieh, C. M., Chen, Y. C., Wang, Y. C., Ho, H. O. & Sheu, M. T., 6月 26 2014, 於: PLoS One. 9, 6, e100321.

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13 引文斯高帕斯（Scopus）

Dried fruit of the Luffa sponge as a source of chitin for applications as skin substitutes

Jiang, P. L., Chien, M. Y., Sheu, M. T., Huang, Y. Y., Chen, M. H., Su, C-H. & Liu, D. Z., 2014, 於: BioMed Research International. 2014, 458287.

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11 引文斯高帕斯（Scopus）

Physical and dissolution characterization of cilostazol solid dispersions prepared by hot melt granulation (HMG) and thermal adhesion granulation (TAG) methods

Chen, Y. C., Ho, H. O., Chiou, J. D. & Sheu, M. T., 10月 1 2014, 於: International Journal of Pharmaceutics. 473, 1-2, p. 458-468 11 p.

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21 引文斯高帕斯（Scopus）

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