Nepali Kunal

研究成果

每年研究成果 2008 2012 2013 2014 2015 2016 2017 2020 2021 2022 2023

• 59 文章
• 22 回顧型文獻
• 2 評論/辯論
• 1 章節

每年研究成果

每年研究成果

搜尋結果

• 2023

  Rational design of synthetically tractable HDAC6/HSP90 dual inhibitors to destroy immune-suppressive tumor microenvironment

  Wu, T. Y., Chen, M., Chen, I. C., Chen, Y. J., Chen, C. Y., Wang, C. H., Cheng, J. J., Nepali, K., Chuang, K. H. & Liou, J. P., 4月 2023, 於: Journal of Advanced Research. 46, p. 159-171

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Growth Inhibition 100%
  • Addition Compound 51%
  • Effector 45%
  • Antineoplastic Agent 37%
  • Drug 22%
  2 引文 斯高帕斯（Scopus）

• Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects

  Nepali, K., Wu, A. C., Lo, W. L., Chopra, B., Lai, M. J., Chuang, J. Y. & Liou, J. P., 2月 2023, 於: European Journal of Medicinal Chemistry. 248, 115054.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Donepezil 100%
  • Anti Alzheimer 96%
  • Hydroxamic Acid 79%
  • Glioblastoma 64%
  • Agonist 62%
• 2022

  Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier

  Sharma, R., Chatterjee, E., Mathew, J., Sharma, S., Rao, N. V., Pan, C. H., Lee, S. B., Dhingra, A., Grewal, A. S., Liou, J. P., Guru, S. K. & Nepali, K., 10月 5 2022, 於: European Journal of Medicinal Chemistry. 240, 114602.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • 2,3-trimethylene-4-quinazolone 100%
  • Deoxyvasicinone 76%
  • Nanocarrier 44%
  • Inhibitory Concentration 50 37%
  • Quinazolinones 36%
  2 引文 斯高帕斯（Scopus）

• Protective effect of Grewia asiatica leaves extract in animal models of epilepsy and anxiety

  Kaur, S., Singh, A., Singh, H., Singh Bedi, P. M., Nepali, K., Singh, B. & Kaur, S., 7月 2022, 於: Journal of Ayurveda and Integrative Medicine. 13, 3, 100616.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Grewia 100%
  • Anxiolytic Agent 72%
  • Anticonvulsant 60%
  • Anti-Anxiety Agents 57%
  • Leaf Like Crystal 44%

• Switch Pocket Kinase: An Emerging Therapeutic Target for the Design of Anticancer Agents

  Kaur, C., Sharma, B. & Nepali, K., 2022, 於: Anti-Cancer Agents in Medicinal Chemistry. 22, 15, p. 2662-2670 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Antineoplastic Agents 100%
  • Phosphotransferases 80%
  • Enzymes 38%
  • Protein Kinases 32%
  • Adenosine Triphosphate 27%
• 2021

  A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling

  Chang, T. Y., Nepali, K., Chen, Y. Y., Yang, Y. C. S. H., Hsu, K. C., Yen, Y., Pan, S. L., Liou, J. P. & Lee, S. B., 6月 2021, 於: Biomedicine and Pharmacotherapy. 138, 111485.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 99%
  • Cell Cycle Checkpoints 83%
  • Mitosis 28%
  • Epigenomics 24%
  4 引文 斯高帕斯（Scopus）

• Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent

  Ojha, R., Chen, I. C., Hsieh, C. M., Nepali, K., Lai, R. W., Hsu, K. C., Lin, T. E., Pan, S. L., Chen, M. C. & Liou, J. P., 2021, (接受/付印) 於: Journal of Medicinal Chemistry. 64, 24, p. 17824-17845 22 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Pargyline 100%
  • Hydroxamic Acid 76%
  • Histone Deacetylase Inhibitors 73%
  • Antiproliferative 62%
  • Bioavailability 61%
  6 引文 斯高帕斯（Scopus）

• Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma

  Nepali, K., Hsu, T. I., Hsieh, C. M., Lo, W. L., Lai, M. J., Hsu, K. C., Lin, T. E., Chuang, J. Y. & Liou, J. P., 5月 5 2021, 於: European Journal of Medicinal Chemistry. 217, 113338.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Memantine 100%
  • Histone Deacetylase Inhibitors 70%
  • Glioblastoma 59%
  • Hydroxamic Acid 48%
  • Permeability 48%
  11 引文 斯高帕斯（Scopus）

• The HDAC/HSP90 inhibitor G570 attenuated blue light-induced cell migration in RPE cells and neovascularization in mice through decreased VEGF production

  Hsu, T. J., Nepali, K., Tsai, C. H., Imtiyaz, Z., Lin, F. L., Hsiao, G., Lai, M. J. & Cheng, Y. W., 7月 2 2021, 於: Molecules. 26, 14, 4359.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • angiogenesis 100%
  • Retinal Pigment 90%
  • degeneration 84%
  • epithelium 83%
  • Histone Deacetylase Inhibitors 78%
  2 引文 斯高帕斯（Scopus）
• 2020

  Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo

  Ojha, R., Nepali, K., Chen, C. H., Chuang, K. H., Wu, T. Y., Lin, T. E., Hsu, K. C., Chao, M. W., Lai, M. J., Lin, M. H., Huang, H. L., Chang, C. D., Pan, S. L., Chen, M. C. & Liou, J. P., 3月 15 2020, 於: European Journal of Medicinal Chemistry. 190, 112086.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • 50 Percent Growth Inhibition 100%
  • compound 17 97%
  • Lung Neoplasms 58%
  • Inhibitory Concentration 50 53%
  • Lung 39%
  20 引文 斯高帕斯（Scopus）

• Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

  Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., 2月 1 2020, 於: European Journal of Medicinal Chemistry. 187, 111915.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Azepines 100%
  • Azepine 76%
  • Histone 60%
  • Protective 46%
  • Cognitive Dysfunction 46%
  9 引文 斯高帕斯（Scopus）

• Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors

  Nepali, K., Chang, T. Y., Lai, M. J., Hsu, K. C., Yen, Y., Lin, T. E., Lee, S. B. & Liou, J. P., 6月 15 2020, 於: European Journal of Medicinal Chemistry. 196, 112291.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Chidamide 95%
  • Benzamide 80%
  • Histone Deacetylase Inhibitors 79%
  • purine 78%
  • Histone 73%
  26 引文 斯高帕斯（Scopus）
• 2019

  1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

  Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., 1月 15 2019, 於: European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • indoline 100%
  • Benzamides 91%
  • Histone Deacetylases 63%
  • Tubulin 58%
  • Histone 58%
  28 引文 斯高帕斯（Scopus）

• Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells

  Nepali, K., Lin, M. H., Chao, M. W., Peng, S. J., Hsu, K. C., Eight Lin, T., Chen, M. C., Lai, M. J., Pan, S. L. & Liou, J. P., 10月 1 2019, 於: Bioorganic Chemistry. 91, 103119.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • resorcinol 100%
  • quinoline 91%
  • Growth Inhibitors 83%
  • PC-3 Cells 78%
  • Amides 75%
  10 引文 斯高帕斯（Scopus）

• Benzoflavone derivatives as potent antihyperuricemic agents

  Singh, J. V., Mal, G., Kaur, G., Gupta, M. K., Singh, A., Nepali, K., Singh, H., Sharma, S. & Bedi, S. P. M., 1月 1 2019, 於: MedChemComm. 10, 1, p. 128-147 20 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Benzoflavones 100%
  • Antihyperuricemic 97%
  • Gout Suppressants 91%
  • Xanthine Oxidase 60%
  • Xanthine 55%
  21 引文 斯高帕斯（Scopus）
• 2018

  (N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo

  Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., 2月 8 2018, 於: Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Quinolines 100%
  • Histone Deacetylase 6 94%
  • Histone Deacetylase Inhibitors 68%
  • Histone 62%
  • Multiple Myeloma 57%
  56 引文 斯高帕斯（Scopus）

• 1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

  Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., 4月 25 2018, 於: European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Hydroxamic Acids 100%
  • 50 Percent Growth Inhibition 83%
  • Histone Deacetylase Inhibitors 72%
  • Antineoplastic Agents 59%
  • Antineoplastic Agent 54%
  31 引文 斯高帕斯（Scopus）

• Antitumour, acute toxicity and molecular modeling studies of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one against Ehrlich ascites carcinoma and sarcoma-180

  Kumar, D., Sharma, P., Nepali, K., Mahajan, G., Mintoo, M. J., Singh, A., Singh, G., Mondhe, D. M., Singh, G., Jain, S. K., Gupta, G. K. & Ntie-Kang, F., 6月 1 2018, 於: Heliyon. 4, 6, e00661.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Acute Toxicity 100%
  • Antitumor 76%
  • Maximum Tolerated Dose 71%
  • Acute Toxicity Oral 69%
  • Non Toxic 42%
  8 引文 斯高帕斯（Scopus）

• Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition (Org. Biomol. Chem. (2016) 14 (716-723))

  Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 1月 1 2018, 於: Organic and Biomolecular Chemistry. 16, 25, p. 4734 1 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Dione 100%
  • HSP90 Heat-Shock Proteins 86%
  • Tubulin 70%
  • Antineoplastic Agents 62%
  • Antineoplastic Agent 58%
• 2017

  Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies

  Singh, H., Singh, J. V., Gupta, M. K., Singh, P., Sharma, S., Nepali, K. & Bedi, P. M. S., 1月 1 2017, 於: Bioorganic and Medicinal Chemistry Letters. 27, 4, p. 850-854 5 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Benzoflavones 100%
  • Esterase Inhibitor 78%
  • Anticholesteremic Agents 73%
  • Sterol Esterase 69%
  • compound A 12 65%
  11 引文 斯高帕斯（Scopus）

• Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms

  Nepali, K., Lee, H-Y., Lai, M-J., Ojha, R., Wu, T. Y., Wu, G. X., Chen, M-C. & Liou, J-P., 2月 15 2017, 於: European Journal of Medicinal Chemistry. 127, p. 115-127 13 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Tubastatin A 100%
  • Carbolines 78%
  • tubastatin A 60%
  • Hydroxamic Acid 58%
  • Histone Deacetylases 55%
  18 引文 斯高帕斯（Scopus）

• Synthesis, screening and docking of fused pyrano[3,2-d]pyrimidine derivatives as xanthine oxidase inhibitor

  Kaur, M., Kaur, A., Mankotia, S., Singh, H., Singh, A., Singh, J. V., Gupta, M. K., Sharma, S., Nepali, K. & Bedi, P. M. S., 1月 1 2017, 於: European Journal of Medicinal Chemistry. 131, p. 14-28 15 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • EC 1.17.3.2 (Xanthine Oxidase) Inhibitor 100%
  • pyrimidine 77%
  • Xanthine Oxidase 77%
  • Xanthine 71%
  • Pyrimidine 56%
  42 引文 斯高帕斯（Scopus）

• Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies

  Singh, H., Singh, J. V., Gupta, M. K., Saxena, A. K., Sharma, S., Nepali, K. & Bedi, P. M. S., 1月 1 2017, 於: Bioorganic and Medicinal Chemistry Letters. 27, 17, p. 3974-3979 6 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Isatin 100%
  • Triazoles 80%
  • coumarin 80%
  • Tubulin 64%
  • Triazole 63%
  87 引文 斯高帕斯（Scopus）
• 2016

  Estimation of crotepoxide in the fruits of Piper attenuatum buch.-ham. using high-performance thin layer chromatography and high- performance liquid chromatography

  Kumar, S., Gauttam, V., Bande, M. S. R., Nepali, K., Tyagi, A. & Dhar, K. L., 1月 1 2016, 於: Current Pharmaceutical Analysis. 12, 4, p. 343-348 6 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • futoxide 100%
  • Piper 65%
  • Thin Layer Chromatography 52%
  • Fruit 41%
  • Occurrence in Nature 36%

• Naphthoflavones as antiproliferative agents: Design, synthesis and biological evaluation

  Kumar, D., Singh, O., Nepali, K., Bedi, P. M. S., Qayum, A., Singh, S. & Jain, S. K., 7月 1 2016, 於: Anti-Cancer Agents in Medicinal Chemistry. 16, 7, p. 881-890 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Cell Line 100%
  • Chalcones 89%
  • compound 20 88%
  • Flavones 82%
  • Phase-Contrast Microscopy 76%
  13 引文 斯高帕斯（Scopus）

• Triazole tethered C₅-curcuminoid-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies

  Singh, H., Kumar, M., Nepali, K., Gupta, M. K., Saxena, A. K., Sharma, S. & Bedi, P. M. S., 6月 30 2016, 於: European Journal of Medicinal Chemistry. 116, p. 102-115 14 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Diarylheptanoids 100%
  • Triazoles 87%
  • coumarin 87%
  • 2-(4-acetoxyphenyl)-2-chloro-N-methylethylamine 75%
  • Tubulin 69%
  75 引文 斯高帕斯（Scopus）
• 2015

  2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

  Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 2015, 於: Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Dione 100%
  • quinoline 93%
  • HSP90 Heat-Shock Proteins 86%
  • Methoxy Group 72%
  • Tubulin 70%
  9 引文 斯高帕斯（Scopus）

• 4,6-diaryl pyrimidones as constrained chalcone analogues: Design, synthesis and evaluation as antiproliferative agents

  Kumar, D., Nepali, K., Bedi, P. M. S., Kumar, S., Malik, F. & Jain, S., 7月 1 2015, 於: Anti-Cancer Agents in Medicinal Chemistry. 15, 6, p. 793-803 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Pyrimidinones 100%
  • Chalcone 88%
  • 5-(3,4-methylenedioxyphenyl)-4-ethyl-2,4-pentadienoic acid piperidide 50%
  • Cell Line 34%
  • Phase-Contrast Microscopy 26%
  12 引文 斯高帕斯（Scopus）

• Anti-cancer pyrimidines in diverse scaffolds: A review of patent literature

  Kaur, R., Kaur, P., Sharma, S., Singh, G., Mehndiratta, S., Bedi, P. M. S. & Nepali, K., 1月 1 2015, 於: Recent Patents on Anti-Cancer Drug Discovery. 10, 1, p. 23-71 49 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Pyrimidines 100%
  • pyrimidine 85%
  • Patents 84%
  • Pyrimidine 62%
  • Literature 29%
  90 引文 斯高帕斯（Scopus）

• Design, synthesis and evaluation of 2,4-diarylpyrano[3,2-c]chromen-5(4H)-one as a new class of non-purine xanthine oxidase inhibitors

  Virdi, H. S., Sharma, S., Mehndiratta, S., Bedi, P. M. S. & Nepali, K., 9月 3 2015, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 30, 5, p. 730-736 7 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • EC 1.17.3.2 (Xanthine Oxidase) Inhibitor 100%
  • Xanthine Oxidase 77%
  • Lewis Acids 61%
  • Chalcones 50%
  • Coumarins 44%
  27 引文 斯高帕斯（Scopus）

• Screening of a library of 4-aryl/heteroaryl-4H-fused pyrans for xanthine oxidase inhibition: Synthesis, biological evaluation and docking studies

  Kaur, R., Naaz, F., Sharma, S., Mehndiratta, S., Gupta, M. K., Bedi, P. M. S. & Nepali, K., 8月 23 2015, 於: Medicinal Chemistry Research. 24, 8, p. 3334-3349 16 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Pyrans 100%
  • Xanthine Oxidase 74%
  • Xanthine 68%
  • Evaluation Studies 54%
  • Libraries 53%
  53 引文 斯高帕斯（Scopus）
• 2014

  4,6-Diaryl/heteroarylpyrimidin-2(1H)-ones as a new class of xanthine oxidase inhibitors

  Shukla, S., Kumar, D., Ojha, R., Gupta, M. K., Nepali, K. & Bedi, P. M. S., 1月 1 2014, 於: Archiv der Pharmazie. 347, 7, p. 486-495 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • EC 1.17.3.2 (Xanthine Oxidase) Inhibitor 100%
  • Xanthine Oxidase 77%
  • Xanthine 71%
  • fluoroboric acid 71%
  • 2,3-dihydro-6-(2,5-dimethoxyphenyl)imidazo(2,1-b)thiazole 69%
  24 引文 斯高帕斯（Scopus）

• Anti-asthmatic activity of azepino [2, 1-b] quinazolones, synthetic analogues of vasicine, an alkaloid from Adhatoda vasica

  Rayees, S., Satti, N. K., Mehra, R., Nargotra, A., Rasool, S., Sharma, A., Sahu, P. K., Rajnikant, Gupta, V. K., Nepali, K. & Singh, G., 8月 5 2014, 於: Medicinal Chemistry Research. 23, 9, p. 4269-4279 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • vasicine 100%
  • Justicia 86%
  • Anti-Asthmatic Agents 71%
  • Alkaloids 55%
  • Alkaloid 44%
  16 引文 斯高帕斯（Scopus）

• Chalcone based azacarboline analogues as novel antitubulin agents: Design, synthesis, biological evaluation and molecular modelling studies

  Sharma, S., Kaur, C., Budhiraja, A., Nepali, K., Gupta, M. K., Saxena, A. K. & Bedi, P. M. S., 10月 6 2014, 於: European Journal of Medicinal Chemistry. 85, p. 648-660 13 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Chalcone 100%
  • Tubulin 71%
  • Inhibitory Concentration 50 39%
  • Indoles 35%
  • Colchicine 28%
  40 引文 斯高帕斯（Scopus）

• Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors

  Sharma, S., Sharma, K., Ojha, R., Kumar, D., Singh, G., Nepali, K. & Bedi, P. M. S., 1月 15 2014, 於: Bioorganic and Medicinal Chemistry Letters. 24, 2, p. 495-500 6 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • fluoroboric acid 100%
  • EC 1.17.3.2 (Xanthine Oxidase) Inhibitor 70%
  • Naphthopyran 70%
  • Xanthine Oxidase 54%
  • Microwaves 52%
  43 引文 斯高帕斯（Scopus）

• Synthesis and cytotoxicity studies of 3,5-diaryl N-acetyl pyrazoline - Isatin hybrids

  Sharma, M., Sharma, S., Buddhiraja, A., Saxena, A. K., Nepali, K. & Bedi, P. M. S., 10月 1 2014, 於: Medicinal Chemistry Research. 23, 10, p. 4337-4344 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Isatin 100%
  • Triazoles 40%
  • Cell Line 35%
  • Triazole 31%
  • HeLa Cells 29%
  31 引文 斯高帕斯（Scopus）

• Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors This Letter is dedicated to Dr. K. L. Dhar on the occasion of his 78th birthday.

  Singh, H., Sharma, S., Ojha, R., Gupta, M. K., Nepali, K. & Bedi, P. M. S., 9月 1 2014, 於: Bioorganic and Medicinal Chemistry Letters. 24, 17, p. 4192-4197 6 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • EC 1.17.3.2 (Xanthine Oxidase) Inhibitor 100%
  • Xanthine Oxidase 77%
  • Xanthine 71%
  • Purine 63%
  • Inhibitory Concentration 50 38%
  45 引文 斯高帕斯（Scopus）
• 2013

  Aza analogs of flavones as potential antimicrobial agents

  Sharma, S., Thakur, V., Ojha, R., Budhiraja, A., Nepali, K. & Singh Bedi, P. M., 5月 1 2013, 於: Letters in Drug Design and Discovery. 10, 4, p. 327-334 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Flavones 100%
  • flavone 97%
  • Flavone 79%
  • Quinolones 78%
  • Anti-Infective Agents 69%
  7 引文 斯高帕斯（Scopus）

• Bioactive metabolites from an endophytic fungus of Aspergillus species isolated from seeds of Gloriosa superba Linn.

  Budhiraja, A., Nepali, K., Sapra, S., Gupta, S., Kumar, S. & Dhar, K. L., 1月 1 2013, 於: Medicinal Chemistry Research. 22, 1, p. 323-329 7 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Aspergillus 100%
  • Seeds 89%
  • Fungi 79%
  • Metabolite 61%
  • Antimicrobial Agent 61%
  41 引文 斯高帕斯（Scopus）

• Design, synthesis and evaluation of arylidene pyrrolo and pyrido fused quinazolones as antimicrobial agents

  Nepali, K., Ojha, R., Singh, A., Budhiraja, A., Bedi, P. M. S. & Dhar, K. L., 7月 1 2013, 於: Letters in Drug Design and Discovery. 10, 6, p. 522-528 7 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Salmonella typhimurium 100%
  • Bacillus subtilis 94%
  • Anti-Infective Agents 88%
  • Candida albicans 87%
  • Pseudomonas aeruginosa 80%
  5 引文 斯高帕斯（Scopus）

• Design and synthesis of aza-flavones as a new class of xanthine oxidase inhibitors

  Dhiman, R., Sharma, S., Singh, G., Nepali, K. & Singh Bedi, P. M., 1月 1 2013, 於: Archiv der Pharmazie. 346, 1, p. 7-16 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • EC 1.17.3.2 (Xanthine Oxidase) Inhibitor 100%
  • Flavones 93%
  • Xanthine Oxidase 77%
  • Xanthine 71%
  • Flavone 61%
  59 引文 斯高帕斯（Scopus）

• Isolation of New Cyclohexyl Epoxide from the Fruits of Piper attenuatum

  Kumar, S., Mehndiratta, S., Nepali, K., Sapra, S., Koul, S. & Dhar, K. L., 1月 1 2013, 於: Natural Products Journal. 3, 4, p. 249-251 3 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • futoxide 100%
  • Piper 65%
  • Epoxy Compounds 58%
  • Benzoate 44%
  • Fruit 41%

• Possible involvement of PPAR-γ in the anticonvulsant effect of aegle marmelos (L.) correa

  Bhatti, R., Singh, J., Nepali, K. & Ishar, M. P. S., 8月 1 2013, 於: Neurochemical Research. 38, 8, p. 1624-1631 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Aegle 100%
  • Peroxisome Proliferator-Activated Receptors 70%
  • Anticonvulsant 68%
  • Anticonvulsants 55%
  • Leaf Like Crystal 49%
  8 引文 斯高帕斯（Scopus）

• Quantitative determination of a novel pseudoalkaloid colchatetralene isolated from the mycoflora of Gloriosa superba Linn by HPTLC

  Budhiraja, A., Nepali, K., Gouttam, V., Sapra, S. & Dhar, K. L., 1月 1 2013, 於: Natural Products Journal. 3, 3, p. 176-181 6 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Thin Layer Chromatography 100%
  • Alkaloid 74%
  • Sample Preparation 69%
  • Chloroform 68%
  • Plate Like Crystal 65%

• Structure activity relationship of arylidene pyrrolo and pyrido [2,1-b] quinazolones as cytotoxic agents: Synthesis, SAR studies, biological evaluation and docking studies

  Mangla, V., Nepali, K., Singh, G., Singh, J., Guru, S., Gupta, M. K., Mahajan, P., Saxena, A. K. & Dhar, K. L., 8月 1 2013, 於: Medicinal Chemistry. 9, 5, p. 642-650 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Cytotoxic Agent 100%
  • Structure-Activity Relationship 93%
  • Cytotoxins 89%
  • Tubulin 85%
  • Evaluation Studies 71%
  9 引文 斯高帕斯（Scopus）

• Synthesis of 1,2,3-triazole tethered bifunctional hybrids by click chemistry and their cytotoxic studies

  Singh, J., Sharma, S., Saxena, A. K., Nepali, K. & Bedi, P. M. S., 7月 1 2013, 於: Medicinal Chemistry Research. 22, 7, p. 3160-3169 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Click Chemistry 100%
  • Triazoles 84%
  • 1,2,3-triazole 73%
  • Chalcones 72%
  • Triazole 66%
  27 引文 斯高帕斯（Scopus）
• 2012

  Antitussive effects of azepino[2,1-b]quinazolones

  Nepali, K., Bande, M. S., Sapra, S., Garg, A., Kumar, S., Sharma, P., Goyal, R., Satti, N. K., Suri, O. P. & Dhar, K. L., 7月 1 2012, 於: Medicinal Chemistry Research. 21, 7, p. 1271-1277 7 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • 7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one 100%
  • Antitussive 92%
  • Antitussive Agents 84%
  • Cough 55%
  • Citric Acid 42%
  10 引文 斯高帕斯（Scopus）

• Effect of nitrogen insertion on the antitussive properties of menthol and camphor

  Kumar, N., Nepali, K., Sapra, S., Bijjem, K. R. V., Kumar, R., Suri, O. P. & Dhar, K. L., 4月 1 2012, 於: Medicinal Chemistry Research. 21, 4, p. 531-537 7 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Antitussive 100%
  • Camphor 98%
  • Antitussive Agents 91%
  • Menthol 89%
  • (-)-Menthol 86%
  12 引文 斯高帕斯（Scopus）

• Effect of ring A and ring B substitution on the cytotoxic potential of pyrazole tethered chalcones

  Nepali, K., Kadian, K., Ojha, R., Dhiman, R., Garg, A., Singh, G., Buddhiraja, A., Bedi, P. M. S. & Dhar, K. L., 10月 1 2012, 於: Medicinal Chemistry Research. 21, 10, p. 2990-2997 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Chalcones 100%
  • Pyrazole 65%
  • Substitution Reaction 39%
  • Pyrazoles 38%
  • furan 32%
  26 引文 斯高帕斯（Scopus）

• Evaluation of antiasthmatic activity of 7,8,9, 10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one in combination with ambroxol in Guinea pigs

  Bande, M., Nepali, K., Goyal, R., Thakur, V., Suri, J., Budhiraja, R. D., Suri, O. P., Singh Bedi, P. M. & Dhar, K. L., 12月 1 2012, 於: Medicinal Chemistry Research. 21, 12, p. 4158-4167 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • 7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one 100%
  • Ambroxol 65%
  • Anti-Asthmatic Agents 55%
  • Bronchodilator Agents 44%
  • Expectorants 36%
  2 引文 斯高帕斯（Scopus）