陳 顧中

研究成果

每年研究成果 1999 2009 2010 2012 2017 2019 2022

• 81 文章
• 2 評論/辯論
• 2 Erratum

每年研究成果

每年研究成果

搜尋結果

• 2016

  The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death

  Chen, P. H., Chang, C. K., Shih, C. M., Cheng, C. H., Lin, C. W., Lee, C. C., Liu, A. J., Ho, K. H. & Chen, K. C., 11月 1 2016, 於: Neuropharmacology. 110, p. 362-375 14 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • xanthohumol 100%
  • Glioma 53%
  • Cell Death 44%
  • MicroRNAs 30%
  • Humulus 20%
  60 引文 斯高帕斯（Scopus）
• 2017

  Antroquinonol, a ubiquinone derivative from the mushroom antrodia camphorata, inhibits colon cancer stem cell-like properties: Insights into the molecular mechanism & inhibitory targets

  Lin, H. C., Lin, M. H., Liao, J. H., Wu, T. H., Lee, T. H., Mi, F. L., Wu, C. H., Chen, K. C., Cheng, C. H. & Lin, C. W., 2017, 於: Journal of Agricultural and Food Chemistry. 65, 1, p. 51-59 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • antroquinonol 100%
  • antroquinonols 99%
  • Antroquinonol 97%
  • Antrodia 81%
  • Taiwanofungus camphoratus 79%
  40 引文 斯高帕斯（Scopus）

• Dietary flavonoids, luteolin and quercetin, inhibit invasion of cervical cancer by reduction of UBE2S through epithelial-mesenchymal transition signaling

  Lin, T. H., Hsu, W. H., Tsai, P. H., Huang, Y. T., Lin, C. W., Chen, K. C., Tsai, I. H., Kandaswami, C. C., Huang, C. J., Chang, G. D., Lee, M. T. & Cheng, C. H., 4月 1 2017, 於: Food and Function. 8, 4, p. 1558-1568 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • uterine cervical neoplasms 100%
  • Luteolin 98%
  • luteolin 84%
  • Quercetin 82%
  • Ligases 77%
  57 引文 斯高帕斯（Scopus）

• Identification of IGF-1-enhanced cytokine expressions targeted by miR-181d in glioblastomas via an integrative miRNA/mRNA regulatory network analysis

  Ho, K. H., Chen, P. H., Hsi, E., Shih, C. M., Chang, W. C., Cheng, C. H., Lin, C. W. & Chen, K. C., 12月 1 2017, 於: Scientific Reports. 7, 1, 732.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Somatomedins 100%
  • Glioblastoma 92%
  • MicroRNAs 79%
  • Cytokines 58%
  • Messenger RNA 53%
  22 引文 斯高帕斯（Scopus）

• microRNA let-7g suppresses PDGF-induced conversion of vascular smooth muscle cell into the synthetic phenotype

  Wang, T. M., Chen, K. C., Hsu, P. Y., Lin, H. F., Wang, Y. S., Chen, C. Y., Liao, Y. C. & Juo, S. H. H., 12月 2017, 於: Journal of Cellular and Molecular Medicine. 21, 12, p. 3592-3601 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Platelet-Derived Growth Factor 100%
  • Vascular Smooth Muscle 84%
  • MAP Kinase Kinase Kinase 1 79%
  • Smooth Muscle Myocytes 76%
  • MicroRNAs 72%
  37 引文 斯高帕斯（Scopus）

• Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ

  Lee, W. Y., Chen, P. C., Wu, W. S., Wu, H. C., Lan, C. H., Huang, Y. H., Cheng, C. H., Chen, K. C. & Lin, C. W., 11月 1 2017, 於: International Journal of Cancer. 141, 9, p. 1921-1931 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Panobinostat 100%
  • Gefitinib 78%
  • ErbB Receptors 59%
  • Non-Small Cell Lung Carcinoma 56%
  • Histone Deacetylase Inhibitors 9%
  32 引文 斯高帕斯（Scopus）

• Podocalyxin-like protein 1 regulates TAZ signaling and stemness properties in colon cancer

  Lee, W. Y., Kuo, C. C., Lin, B. X., Cheng, C. H., Chen, K. C. & Lin, C. W., 10月 1 2017, 於: International Journal of Molecular Sciences. 18, 10, 2047.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • podocalyxin 100%
  • cancer 57%
  • Proteins 55%
  • Colonic Neoplasms 55%
  • proteins 48%
  13 引文 斯高帕斯（Scopus）

• The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity

  Chen, P. H., Shen, W. L., Shih, C-M., Ho, K. H., Cheng, C-H., Lin, C-W., Lee, C-C., Liu, A. J. & Chen, K-C., 4月 1 2017, 於: Neuropharmacology. 116, p. 300-314 15 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Temozolomide 100%
  • Glioma 74%
  • Glioblastoma 26%
  • Poly(ADP-ribose) Polymerases 15%
  • Notch3 Receptor 12%
  27 引文 斯高帕斯（Scopus）

• The microRNA-302b-inhibited insulin-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor IA

  Lee, C. C., Chen, P. H., Ho, K. H., Shih, C. M., Cheng, C. H., Lin, C. W., Cheng, K. T., Liu, A. J. & Chen, K. C., 3月 1 2017, 於: PLoS One. 12, 3, e0173890.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • glioblastoma 100%
  • Insulin-Like Growth Factor Binding Protein 2 97%
  • glioma 89%
  • insulin-like growth factor binding proteins 87%
  • microRNA 69%
  16 引文 斯高帕斯（Scopus）
• 2018

  Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

  Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., 6月 2018, 於: Journal of Cellular Physiology. 233, 6, p. 4972-4980 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Nicotine 100%
  • Epithelial-Mesenchymal Transition 84%
  • Fibroblasts 60%
  • Breast Neoplasms 51%
  • Growth Factor 47%
  17 引文 斯高帕斯（Scopus）

• Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction

  Chen, K. C., Hsu, W. H., Ho, J. Y., Lin, C. W., Chu, C. Y., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., 7月 2018, 於: Journal of Food and Drug Analysis. 26, 3, p. 1180-1191 12 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Luteolin 100%
  • metastasis 91%
  • luteolin 85%
  • Quercetin 82%
  • Flavonoids 72%
  46 引文 斯高帕斯（Scopus）

• Gene landscape and correlation between B-cell infiltration and programmed death ligand 1 expression in lung adenocarcinoma patients from The Cancer Genome Atlas data set

  Ho, K-H., Chang, C-J., Huang, T-W., Shih, C-M., Liu, A-J., Chen, P-H., Cheng, K-T. & Chen, K-C., 12月 1 2018, 於: PLoS One. 13, 12, p. e0208459 e0208459.

  研究成果: 雜誌貢獻 › 文章 › 同行評審
  18 引文 斯高帕斯（Scopus）

• microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells

  Chen, P. H., Liu, A. J., Ho, K. H., Chiu, Y. T., Anne Lin, Z. H., Lee, Y. T., Shih, C. M. & Chen, K. C., 8月 1 2018, 於: Chemico-Biological Interactions. 291, p. 144-151 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Imatinib 100%
  • Imatinib Mesylate 76%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 70%
  • Myeloid Cells 68%
  • Autophagy 64%
  21 引文 斯高帕斯（Scopus）

• miR-4725-3p targeting stromal interacting molecule 1 signaling is involved in xanthohumol inhibition of glioma cell invasion

  Ho, K. H., Chang, C. K., Chen, P. H., Wang, Y. J., Chang, W. C. & Chen, K. C., 8月 1 2018, 於: Journal of Neurochemistry. 146, 3, p. 269-288 20 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • xanthohumol 100%
  • Xanthohumol 99%
  • Glioma 53%
  • Glioblastoma 24%
  • Humulus 23%
  19 引文 斯高帕斯（Scopus）
• 2019

  Dietary flavonoids luteolin and quercetin inhibit migration and invasion of squamous carcinoma through reduction of src/stat3/s100a7 signaling

  Fan, J. J., Hsu, W. H., Lee, K. H., Chen, K. C., Lin, C. W., Lee, Y. L. A., Ko, T. P., Lee, L. T., Lee, M. T., Chang, M. S. & Cheng, C. H., 11月 2019, 於: Antioxidants. 8, 11, 557.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Luteolin 100%
  • Quercetin 82%
  • S3I-201 81%
  • Flavonoids 72%
  • Flavonoid 68%
  54 引文 斯高帕斯（Scopus）

• IGF-1-enhanced miR-513a-5p signaling desensitizes glioma cells to temozolomide by targeting the NEDD4L-inhibited Wnt/β-catenin pathway

  Chen, K. C., Chen, P. H., Ho, K. H., Shih, C. M., Chou, C. M., Cheng, C. H. & Lee, C. C., 1月 1 2019, 於: PLoS ONE. 14, 12, e0225913.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • catenins 100%
  • Temozolomide 96%
  • glioma 78%
  • Catenins 75%
  • somatomedins 69%
  24 引文 斯高帕斯（Scopus）

• miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme

  Ho, K. H., Cheng, C. H., Chou, C. M., Chen, P. H., Liu, A. J., Lin, C. W., Shih, C. M. & Chen, K. C., 9月 2019, 於: Pharmacological Research. 147, 104390.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Cathepsin B 100%
  • Temozolomide 95%
  • Glioblastoma 75%
  • MicroRNAs 64%
  • Atlases 15%
  27 引文 斯高帕斯（Scopus）

• Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells

  Wong, J. H., Wang, Y. S., Nam, S., Ho, K. H., Chang, C. M., Chen, K. C., Chen, Y. F. & Chang, W. C., 1月 1 2019, 於: Environmental Toxicology. 34, 11, p. 1191-1198 8 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Plasticizers 100%
  • phthalic acid 98%
  • phthalate 84%
  • Phthalate 80%
  • Cyclooxygenase 2 75%
  10 引文 斯高帕斯（Scopus）

• Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells

  Fan, J. J., Hsu, W. H., Hung, H. H., Zhang, W. J., A Lee, Y. L., Chen, K. C., Chu, C. Y., Ko, T. P., Lee, M. T., Lin, C. W. & Cheng, C. H., 5月 2019, 於: International Journal of Oncology. 54, 5, p. 1639-1650 12 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Superoxide Dismutase 100%
  • Squamous Cell Carcinoma 90%
  • Reactive Oxygen Species 38%
  • diphenyleneiodonium 35%
  • Luteolin 33%
  10 引文 斯高帕斯（Scopus）

• TACCO, a Database Connecting Transcriptome Alterations, Pathway Alterations and Clinical Outcomes in Cancers

  Chou, P. H., Liao, W. C., Tsai, K. W., Chen, K. C., Yu, J. S. & Chen, T. W., 12月 1 2019, 於: Scientific Reports. 9, 1, 3877.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Critical Pathways 100%
  • Transcriptome 79%
  • Databases 51%
  • Neoplasms 27%
  • Formal Social Control 17%
  15 引文 斯高帕斯（Scopus）
• 2020

  A Key Role of DNA Damage-Inducible Transcript 4 (DDIT4) Connects Autophagy and GLUT3-Mediated Stemness To Desensitize Temozolomide Efficacy in Glioblastomas

  Ho, K. H., Chen, P. H., Chou, C. M., Shih, C. M., Lee, Y. T., Cheng, C. H. & Chen, K. C., 7月 1 2020, 於: Neurotherapeutics. 17, 3, p. 1212-1227 16 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Temozolomide 100%
  • Glioblastoma 79%
  • Autophagy 77%
  • DNA Damage 70%
  • Activating Transcription Factor 4 15%
  13 引文 斯高帕斯（Scopus）

• Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

  Wong, J. Y. Y., Zhang, H., Hsiung, C. A., Shiraishi, K., Yu, K., Matsuo, K., Wong, M. P., Hong, Y. C., Wang, J., Seow, W. J., Wang, Z., Song, M., Kim, H. N., Chang, I. S., Chatterjee, N., Hu, W., Wu, C., Mitsudomi, T., Zheng, W., Kim, J. H., 及其他166Seow, A., Caporaso, N. E., Shin, M. H., Chung, L. P., An, S. J., Wang, P., Yang, Y., Zheng, H., Yatabe, Y., Zhang, X. C., Kim, Y. T., Cai, Q., Yin, Z., Kim, Y. C., Bassig, B. A., Chang, J., Ho, J., Ji, B. T., Daigo, Y., Ito, H., Momozawa, Y., Ashikawa, K., Kamatani, Y., Honda, T., Hosgood, H. D., Sakamoto, H., Kunitoh, H., Tsuta, K., Watanabe, S. I., Kubo, M., Miyagi, Y., Nakayama, H., Matsumoto, S., Tsuboi, M., Goto, K., Shi, J., Song, L., Hua, X., Takahashi, A., Goto, A., Minamiya, Y., Shimizu, K., Tanaka, K., Wei, F., Matsuda, F., Su, J., Kim, Y. H., Oh, I. J., Song, F., Su, W. C., Chen, Y. M., Chang, G. C., Chen, K. Y., Huang, M. S., Chien, L. H., Xiang, Y. B., Park, J. Y., Kweon, S. S., Chen, C. J., Lee, K. M., Blechter, B., Li, H., Gao, Y. T., Qian, B., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Wang, W. C., Chung, C. C., Burdett, L., Yeager, M., Hutchinson, A., Berndt, S. I., Wu, W., Pang, H., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Liu, L., Kang, C. H., Zhu, M., Chen, C. H., Yang, T. Y., Xu, J., Guan, P., Tan, W., Wang, C. L., Hsin, M., Sit, K. Y., Ho, J., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Lin, C. C., Park, I. K., Xu, P., Wang, Y., He, Q., Perng, R. P., Chen, C. Y., Vermeulen, R., Wu, J., Lim, W. Y., Chen, K. C., Li, Y. J., Li, J., Chen, H., Yu, C. J., Jin, L., Chen, T. Y., Jiang, S. S., Liu, J., Yamaji, T., Hicks, B., Wyatt, K., Li, S. A., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Li, X., Ren, Y., Cui, P., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Yang, K., Jiang, G., Fei, K., Wu, G., Lin, H. C., Chen, H. L., Fang, Y. H., Tsai, F. Y., Hsieh, W. S., Yu, J., Stevens, V. L., Laird-Offringa, I. A., Marconett, C. N., Rieswijk, L., Chao, A., Yang, P. C., Shu, X. O., Wu, T., Wu, Y. L., Lin, D., Chen, K., Zhou, B., Huang, Y. C., Kohno, T., Shen, H., Chanock, S. J., Rothman, N. & Lan, Q., 3月 2020, 於: Genomics. 112, 2, p. 1223-1232 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Mendelian Randomization Analysis 100%
  • Adenocarcinoma of Lung 66%
  • Genome-Wide Association Study 64%
  • Tuberculosis 51%
  • Smoking 45%
  7 引文 斯高帕斯（Scopus）

• Xanthohumol regulates miR-4749-5p-inhibited RFC2 signaling in enhancing temozolomide cytotoxicity to glioblastoma

  Ho, K. H., Kuo, T. C., Lee, Y. T., Chen, P. H., Shih, C. M., Cheng, C. H., Liu, A. J., Lee, C. C. & Chen, K. C., 8月 1 2020, 於: Life Sciences. 254, 117807.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • xanthohumol 100%
  • Xanthohumol 99%
  • Temozolomide 94%
  • Replication Protein C 91%
  • Glioblastoma 57%
  18 引文 斯高帕斯（Scopus）
• 2021

  A regulatory loop among CD276, miR-29c-3p, and Myc exists in cancer cells against natural killer cell cytotoxicity

  Lee, C. C., Ho, K. H., Huang, T. W., Shih, C. M., Hsu, S. Y., Liu, A. J. & Chen, K. C., 7月 15 2021, 於: Life Sciences. 277, 119438.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Natural Killer Cells 100%
  • MicroRNAs 90%
  • Molecular Cluster 69%
  • Neoplasms 34%
  • Immunotherapy 27%
  7 引文 斯高帕斯（Scopus）

• Cancer essential genes stratified lung adenocarcinoma patients with distinct survival outcomes and identified a subgroup from the terminal respiratory unit type with different proliferative signatures in multiple cohorts

  Ho, K. H., Huang, T. W., Liu, A. J., Shih, C. M. & Chen, K. C., 5月 1 2021, 於: Cancers. 13, 9, 2128.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Essential Genes 100%
  • Neoplasm Genes 95%
  • Adenocarcinoma of Lung 94%
  • Survival 48%
  • Survival Rate 26%
  8 引文 斯高帕斯（Scopus）

• Glycolysis-associated lncRNAs identify a subgroup of cancer patients with poor prognoses and a high-infiltration immune microenvironment

  Ho, K. H., Huang, T. W., Shih, C. M., Lee, Y. T., Liu, A. J., Chen, P. H. & Chen, K. C., 2月 25 2021, 於: BMC Medicine. 19, 1, p. 59 59.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Long Noncoding RNA 100%
  • Glycolysis 97%
  • Neoplasms 29%
  • Epithelial-Mesenchymal Transition 23%
  • Genes 12%
  13 引文 斯高帕斯（Scopus）

• Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling

  Ho, K. H., Lee, Y. T., Chen, P. H., Shih, C. M., Cheng, C. H. & Chen, K. C., 2021, (接受/付印) 於: Neurotherapeutics. 18, 2, p. 1371-1392 22 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Guanabenz 100%
  • Sunitinib 76%
  • Glioblastoma 59%
  • Autophagy 34%
  • Temozolomide 14%
  5 引文 斯高帕斯（Scopus）
• 2022

  Hypoxia-inducible lncRNA MIR210HG interacting with OCT1 is involved in glioblastoma multiforme malignancy

  Ho, K. H., Shih, C. M., Liu, A. J. & Chen, K. C., 2月 2022, 於: Cancer Science. 113, 2, p. 540-552 13 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Octamer Transcription Factor-1 100%
  • Long Noncoding RNA 63%
  • Glioblastoma 57%
  • Hypoxia 45%
  • Temozolomide 24%
  7 引文 斯高帕斯（Scopus）

• MiR-328-3p Affects Axial Length Via Multiple Routes and Anti-miR-328-3p Possesses a Potential to Control Myopia Progression

  Liang, C. L., Chen, K. C., Hsi, E., Lin, J. Y., Chen, C. Y., Tseng, J. K. & Juo, S. H. H., 11月 2022, 於: Investigative Ophthalmology and Visual Science. 63, 12, 11.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Myopia 100%
  • Fibromodulin 75%
  • Chromatin Immunoprecipitation 33%
  • Eye 27%
  • Transfection 25%

• miR-4286 is Involved in Connections Between IGF-1 and TGF-β Signaling for the Mesenchymal Transition and Invasion by Glioblastomas

  Ho, K. H., Chen, P. H., Shih, C. M., Lee, Y. T., Cheng, C. H., Liu, A. J., Lee, C. C. & Chen, K. C., 4月 2022, 於: Cellular and Molecular Neurobiology. 42, 3, p. 791-806 16 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Somatomedins 100%
  • Transforming Growth Factors 98%
  • Glioblastoma 92%
  • MicroRNAs 79%
  • Signal Transduction 14%
  7 引文 斯高帕斯（Scopus）

• Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment

  Kuo, Y. Y., Ho, K. H., Shih, C. M., Chen, P. H., Liu, A. J. & Chen, K. C., 11月 15 2022, 於: Life Sciences. 309, 121023.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • piperlonguminine 100%
  • Temozolomide 90%
  • Glioblastoma 55%
  • Sphere 31%
  • Adjuvant 23%