每年專案
個人檔案
學歷
- 2011 國立交通大學生物資訊及系統生物研究所博士
- 2007 國立交通大學生物資訊研究所碩士
- 2005 國立交通大學生物科技學系學士
經歷
- 2022- 臺北醫學大學臨床基因體學暨蛋白質體學碩士學位學程教授
- 2022- 臺北醫學大學國際轉譯科學博士學位學程教授
- 2022- 臺北醫學大學癌症生物學與藥物研發研究所教授
- 2022- 臺北醫學大學生技醫療產業研發博士學位學程教授
- 2022- 臺北醫學大學癌症生物學與藥物研發博士學位學程教授
- 2021-2022 臺北醫學大學臨床基因體學暨蛋白質體學碩士學位學程副教授
- 2021-2022 臺北醫學大學國際轉譯科學博士學位學程副教授
- 2019-2022 臺北醫學大學癌症生物學與藥物研發研究所副教授
- 2019-2022 臺北醫學大學生技醫療產業研發博士學位學程副教授
- 2019-2022 臺北醫學大學癌症生物學與藥物研發博士學位學程助理教授
- 2018-2019 臺北醫學大學癌症生物學與藥物研發研究所助理教授
- 2015-2018 臺北醫學大學癌症生物學與藥物研發博士學位學程助理教授
- 2013-2015 國立交通大學約聘助理研究員
- 2011-2013 國立交通大學博士後研究員
研究興趣
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
指紋
- 1 類似的個人檔案
過去五年中的合作和熱門研究領域
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研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究-利用人工智慧與以結構為基礎策略設計與優化新穎DYRK1/CLK抑制劑(2/3)
Hsu, K.-C. (PI)
8/1/24 → 7/31/25
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究-利用人工智慧與以結構為基礎策略設計與優化新穎DYRK1/CLK抑制劑(1/3)
Hsu, K.-C. (PI)
8/1/23 → 7/31/24
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening
Yang, C. L., Wu, Y. W., Tu, H. J., Yeh, Y. H., Lin, T. E., Sung, T. Y., Li, M. C., Yen, S. C., Hsieh, J. H., Yu, M. C., Hsieh, S. Y., Hsieh, H. P., Pan, S. L. & Hsu, K. C., 2025, (接受/付印) 於: Advanced Science.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening
Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., 1月 13 2025, 於: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
PCSK9 Enhances Cardiac Fibrogenesis via the Activation of Toll-like Receptor and NLRP3 Inflammasome Signaling
Chung, C. C., Kao, Y. H., Chen, Y. C., Lin, Y. K., Higa, S., Hsu, K. C. & Chen, Y. J., 3月 2025, 於: International journal of molecular sciences. 26, 5, 1921.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
Structural optimization and biological evaluation of indolin-2-one derivatives as novel CDK8 inhibitors for idiopathic pulmonary fibrosis
Hsu, J. Y., Hsu, K. C., Chou, C. H., He, T. Y., Lin, T. E., Sung, T. Y., Yen, S. C., Hsieh, J. H., Yang, C. R. & Huang, W. J., 3月 2025, 於: Biomedicine and Pharmacotherapy. 184, 117891.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
The Cyclin-Dependent Kinase 8 Inhibitor E966–0530–45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo
Chou, C. H., Huang, W. J., Hsu, K. C., Hsu, J. Y., Lin, T. E. & Yang, C. R., 2025, 於: International Journal of Biological Sciences. 21, 2, p. 685-707 23 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取1 引文 斯高帕斯(Scopus)
資料集
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Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
資料集: Dataset
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Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors
Lin, T. E. (Creator), Sung, L.-C. (Creator), Chao, M.-W. (Creator), Li, M. (Creator), Zheng, J.-H. (Creator), Sung, T.-Y. (Creator), Hsieh, J.-H. (Creator), Yang, C.-R. (Creator), Lee, H.-Y. (Creator), Cho, E.-C. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.17162118.v1, https://tandf.figshare.com/articles/journal_contribution/Structure-based_virtual_screening_and_biological_evaluation_of_novel_small-molecule_BTK_inhibitors/17162118/1
資料集: Dataset
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CCDC 2000792: Experimental Crystal Structure Determination
Hsu, M.-H. (Contributor), Hsieh, C.-Y. (Contributor), Kapoor, M. (Contributor), Chang, J.-H. (Contributor), Chu, H.-L. (Contributor), Cheng, T.-M. (Contributor), Hsu, K.-C. (Contributor), Lin, T. E. (Contributor), Tsai, F.-Y. (Contributor) & Horng, J.-C. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc254zp0, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc254zp0&sid=DataCite
資料集: Dataset
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Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C.-F. (Creator), Hsu, K.-C. (Creator), Huangfu, W.-C. (Contributor), Lin, T. E. (Creator), Huang, H.-L. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.c.4896705.v1, https://springernature.figshare.com/collections/Investigating_the_potential_effects_of_selective_histone_deacetylase_6_inhibitor_ACY1215_on_infarct_size_in_rats_with_cardiac_ischemia-reperfusion_injury/4896705/1
資料集: Dataset
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Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Pan, S.-L. (Contributor), Hsu, K.-C. (Creator), Lin, T. E. (Creator), Lin, C.-F. (Creator), Huang, H.-L. (Contributor) & Huangfu, W.-C. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1
資料集: Dataset