每年專案
個人檔案
學歷
- 2011 國立交通大學生物資訊及系統生物研究所博士
- 2007 國立交通大學生物資訊研究所碩士
- 2005 國立交通大學生物科技學系學士
經歷
- 2022- 臺北醫學大學臨床基因體學暨蛋白質體學碩士學位學程教授
- 2022- 臺北醫學大學國際轉譯科學博士學位學程教授
- 2022- 臺北醫學大學癌症生物學與藥物研發研究所教授
- 2022- 臺北醫學大學生技醫療產業研發博士學位學程教授
- 2022- 臺北醫學大學癌症生物學與藥物研發博士學位學程教授
- 2021-2022 臺北醫學大學臨床基因體學暨蛋白質體學碩士學位學程副教授
- 2021-2022 臺北醫學大學國際轉譯科學博士學位學程副教授
- 2019-2022 臺北醫學大學癌症生物學與藥物研發研究所副教授
- 2019-2022 臺北醫學大學生技醫療產業研發博士學位學程副教授
- 2019-2022 臺北醫學大學癌症生物學與藥物研發博士學位學程助理教授
- 2018-2019 臺北醫學大學癌症生物學與藥物研發研究所助理教授
- 2015-2018 臺北醫學大學癌症生物學與藥物研發博士學位學程助理教授
- 2013-2015 國立交通大學約聘助理研究員
- 2011-2013 國立交通大學博士後研究員
研究興趣
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
指紋
查看啟用 Kai-Cheng Hsu 的研究主題。這些主題標籤來自此人的作品。共同形成了獨特的指紋。
- 1 類似的個人檔案
過去五年中的合作和熱門研究領域
國家/地區層面的近期外部共同作業。按一下圓點深入探索詳細資料，或
專案
- 23 已完成
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研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究－利用人工智慧與以結構為基礎策略設計與優化新穎DYRK1/CLK抑制劑(1/3)
Hsu, K.-C. (PI)
8/1/23 → 7/31/24
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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111年度【產學合作計畫-人工智能技術應用於新穎胰臟癌藥物研發與優化(2/2)】
Hsu, K.-C. (PI)
11/1/22 → 10/31/23
研究計畫: A - 政府部門 › b - 國家科學及技術委員會
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An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., 6月 2024, 於: Protein Science. 33, 6, e5007.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress
Wu, L. H., Cheng, Y. W., Lin, F. L., Hsu, K. C., Wang, M. H., Yen, J. L., Wang, T. J., Lin, T. E., Liu, Y. C., Huang, W. J. & Hsiao, G., 5月 2024, 於: Biomedicine and Pharmacotherapy. 174, 116538.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
Tu, H. J., Chao, M. W., Lee, C. C., Peng, C. S., Wu, Y. W., Lin, T. E., Chang, Y. W., Yen, S. C., Hsu, K. C., Pan, S. L. & HuangFu, W. C., 2024, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 39, 1, 2418470.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
Discovery of Novel Spike Inhibitors against SARS-CoV-2 Infection
Tai, L. T., Yeh, C. Y., Chang, Y. J., Liu, J. F., Hsu, K. C., Cheng, J. C. & Lu, C. H., 6月 2024, 於: International journal of molecular sciences. 25, 11, 6105.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
Disulfiram inhibits coronaviral main protease by conjugating to its substrate entry site
Kuan, Y., Chu, H. F., Hsu, P. H., Hsu, K. C., Lin, T. H., Huang, C. H. & Chen, W. Y., 9月 2024, 於: International Journal of Biological Macromolecules. 276, 133955.研究成果: 雜誌貢獻 › 文章 › 同行評審
資料集
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Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
資料集: Dataset
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Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C.-F. (Creator), Hsu, K.-C. (Creator), Huangfu, W.-C. (Contributor), Lin, T. E. (Creator), Huang, H.-L. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.c.4896705.v1, https://springernature.figshare.com/collections/Investigating_the_potential_effects_of_selective_histone_deacetylase_6_inhibitor_ACY1215_on_infarct_size_in_rats_with_cardiac_ischemia-reperfusion_injury/4896705/1
資料集: Dataset
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Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Pan, S.-L. (Contributor), Hsu, K.-C. (Creator), Lin, T. E. (Creator), Lin, C.-F. (Creator), Huang, H.-L. (Contributor) & Huangfu, W.-C. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1
資料集: Dataset
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CCDC 2000792: Experimental Crystal Structure Determination
Hsu, M.-H. (Contributor), Hsieh, C.-Y. (Contributor), Kapoor, M. (Contributor), Chang, J.-H. (Contributor), Chu, H.-L. (Contributor), Cheng, T.-M. (Contributor), Hsu, K.-C. (Contributor), Lin, T. E. (Contributor), Tsai, F.-Y. (Contributor) & Horng, J.-C. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc254zp0, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc254zp0&sid=DataCite
資料集: Dataset
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Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors
Lin, T. E. (Creator), Sung, L.-C. (Creator), Chao, M.-W. (Creator), Li, M. (Creator), Zheng, J.-H. (Creator), Sung, T.-Y. (Creator), Hsieh, J.-H. (Creator), Yang, C.-R. (Creator), Lee, H.-Y. (Creator), Cho, E.-C. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.17162118.v1, https://tandf.figshare.com/articles/journal_contribution/Structure-based_virtual_screening_and_biological_evaluation_of_novel_small-molecule_BTK_inhibitors/17162118/1
資料集: Dataset