每年專案
個人檔案
學歷
- 2000 臺灣大學醫學院藥研所博士
- 1996 臺灣大學醫學院藥研所碩士
- 1994 臺北醫學院藥學系學士
經歷
- 2021.11- 臺北醫學大學新藥開發研究中心主任
- 2018.01- 臺北醫學大學藥學院院長
- 2017.06- 臺北醫學大學生技醫藥商品化中心主任
- 2015.08-2022.07 臺北醫學大學藥學院生技製藥研究中心主任
- 2013.09-2017.12 臺北醫學大學藥學院副院長
- 2013.08- 臺北醫學大學中草藥臨床藥物研發博士學位學程
- 2013.08- 臺北醫學大學癌症生物學與藥物研發博士學位學程
- 2012.10-2016.12 臺北醫學大學藥物有機合成核心服務實驗室主任
- 2012.08- 臺北醫學大學藥物科學學科教授
- 2012.02-2012.07 臺北醫學大學藥物科學學科副教授
- 2008.02-2012.01 臺北醫學大學藥學系副教授
- 2004.10-2008.01 臺北醫學大學藥學系助理教授
獎項
- 2019 Total Research project Budget Award - Excellence Award, Taipei Medical University
- 2019 Excellent Industry-Academia Collaboration Award, Taipei Medical University
1. EDITORIAL ADVISORY BOARD members, Journal of Medicinal Chemistry (IF = 6.259, CHEMISTRY/MEDICINAL)
2. 2015 Taipei Medical University Teaching Award
3. 2014 Taipei Biotech Awards, Gold “Industry-University Cooperation Award”
4. 2014 TienTe Lee Award, Young Scientist Award
5. 2011 Young scientist award, Ching-Kang Foundation for Pharmacy Promotion
研究興趣
- 抗癌小分子化合物設計與合成
- 有機合成
指紋
- 1 類似的個人檔案
網路
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脂肪酸代謝所調控的神經炎症在構建造成腫瘤復發之神經元-巨噬細胞-膠質瘤迴路中的角色-可穿透血腦障蔽腦障蔽且抑制惡性神經膠母細胞瘤發炎之藥物研發(1/3)
8/1/22 → 7/31/23
研究計畫: A - 政府部門 › b - 科技部
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Rational design of synthetically tractable HDAC6/HSP90 dual inhibitors to destroy immune-suppressive tumor microenvironment
Wu, T. Y., Chen, M., Chen, I. C., Chen, Y. J., Chen, C. Y., Wang, C. H., Cheng, J. J., Nepali, K., Chuang, K. H. & Liou, J. P., 4月 2023, 於: Journal of Advanced Research. 46, p. 159-171研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取2 引文 斯高帕斯(Scopus) -
Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects
Nepali, K., Wu, A. C., Lo, W. L., Chopra, B., Lai, M. J., Chuang, J. Y. & Liou, J. P., 2月 2023, 於: European Journal of Medicinal Chemistry. 248, 115054.研究成果: 雜誌貢獻 › 文章 › 同行評審
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2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors
Wang, Y. S., Yeh, T. K., Chang, W. C., Liou, J. P., Liu, Y. M. & Huang, W. C., 12月 5 2022, 於: European Journal of Medicinal Chemistry. 243, 114773.研究成果: 雜誌貢獻 › 文章 › 同行評審
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Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier
Sharma, R., Chatterjee, E., Mathew, J., Sharma, S., Rao, N. V., Pan, C. H., Lee, S. B., Dhingra, A., Grewal, A. S., Liou, J. P., Guru, S. K. & Nepali, K., 10月 5 2022, 於: European Journal of Medicinal Chemistry. 240, 114602.研究成果: 雜誌貢獻 › 文章 › 同行評審
2 引文 斯高帕斯(Scopus) -
A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model
Yeh, L-Y., Fang, Y-T., Lee, H-S., Liu, C-H., Chen, Y-Y., Lo, Y-C., Laiman, V., Liou, J-P., Chung, K. F., Chuang, H-C. & Lin, C-H., 5月 2022, 於: Frontiers in Medicine. 9, 794025.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取
資料集
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The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells
Tu, H. (Contributor), Lin, Y. (Contributor), Chao, M. (Contributor), Sung, T. (Creator), Wu, Y. (Creator), Chen, Y. (Creator), Lin, M. (Contributor), Liou, J. (Creator), Pan, S. (Contributor) & Yang, C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4350887.v1, https://springernature.figshare.com/collections/The_anticancer_effects_of_MPT0G211_a_novel_HDAC6_inhibitor_combined_with_chemotherapeutic_agents_in_human_acute_leukemia_cells/4350887/1
資料集: Dataset
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Additional file 4: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M. (Contributor), Chang, L. (Contributor), Tu, H. (Contributor), Chang, C. (Contributor), Lai, M. (Contributor), Chen, Y. (Creator), Liou, J. (Creator), Teng, C. (Contributor) & Pan, S. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8202896.v1, https://springernature.figshare.com/articles/Additional_file_4_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202896/1
資料集: Dataset
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Suberoylanilide hydroxamic acid represses glioma stem-like cells
Hsu, C. (Contributor), Chang, W. (Creator), Hsu, T. (Contributor), Liu, J. (Contributor), Yeh, S. (Contributor), Wang, J. (Creator), Liou, J. (Creator), Ko, C. (Contributor), Chang, K. (Creator) & Chuang, J. (Creator), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3596465.v1, https://doi.org/10.6084%2Fm9.figshare.c.3596465.v1
資料集: Dataset
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Additional file 1: of Suberoylanilide hydroxamic acid represses glioma stem-like cells
Chang, K. (Creator), Wang, J. (Creator), Chuang, J. (Creator), Ko, C. (Contributor), Hsu, T. (Contributor), Chang, W. (Creator), Yeh, S. (Contributor), Liou, J. (Creator), Liu, J. (Contributor) & Hsu, C. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3596465_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3596465_d1.v1
資料集: Dataset
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Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M. (Contributor), Chang, L. (Contributor), Tu, H. (Contributor), Chang, C. (Contributor), Lai, M. (Contributor), Chen, Y. (Creator), Liou, J. (Creator), Teng, C. (Contributor) & Pan, S. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4522856.v1, https://springernature.figshare.com/collections/Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/4522856/1
資料集: Dataset