Andrew H.-J. Wang

1996

X-ray crystallographic and NMR structural studies of anthracycline anticancer drugs. Implication in drug design

Wang, A. H. J., 1996, 於: Advances in DNA Sequence-Specific Agents. 2, C, p. 59-100 42 p.

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1995

A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA

Yang, D., van Boom, S. S. G. E., Reedijk, J., van Boom, J. H., Farrell, N. & Wang, A. H. J., 7月 1995, 於: Nature Structural Biology. 2, 7, p. 577-586 10 p.

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68 引文斯高帕斯（Scopus）

Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(Cgtacg) and d(cgatcg): Implications in drug-dna crosslink

Gao, Y. G. & Wang, A. H., 8月 1995, 於: Journal of Biomolecular Structure and Dynamics. 13, 1, p. 103-117 15 p.

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25 引文斯高帕斯（Scopus）

DNA with 2'-5 Phosphodiester Bonds Forms a Duplex Structure in the A-Type Conformation

Robinson, H., Jung, K. E., Switzer, C. & Wang, A. H. J., 1月 1995, 於: Journal of the American Chemical Society. 117, 2, p. 837-838 2 p.

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40 引文斯高帕斯（Scopus）

Electrostatic potential distribution of the gene V protein from Ff phage facilitates cooperative DNA binding: A model of the GVP‐ssDNA complex

Guan, Y., Zhang, H. & Wang, A. H. J., 2月 1995, 於: Protein Science. 4, 2, p. 187-197 11 p.

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26 引文斯高帕斯（Scopus）

Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA

Gao, Y. G., Robinson, H., van Boom, J. H. & Wang, A. H., 1995, 於: Biophysical Journal. 69, 2, p. 559-568 10 p.

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51 引文斯高帕斯（Scopus）

Structure and Isomerization of an Intrastrand Cisplatin-Cross-Linked Octamer DNA Duplex by NMR Analysis

Yang, D., van Boom, S. S. G. E., Reedijk, J., van Boom, J. H. & Wang, A. H. J., 10月 1995, 於: Biochemistry. 34, 39, p. 12912-12920 9 p.

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232 引文斯高帕斯（Scopus）

1994

¹³C-NMR of the Deoxyribose Sugars in Four DNA Oligonucleotide Duplexes: Assignment and Structural Features

LaPlante, S. R., Zanatta, N., Hakkinen, A., Wang, A. H. J. & Borer, P. N., 3月 1 1994, 於: Biochemistry. 33, 9, p. 2430-2440 11 p.

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19 引文斯高帕斯（Scopus）

3-beta-D-ribofuranosyl-6,7-dihydro-9H-thiazolo[3,2-a]purin-9-one hydrate.

Liaw, Y. C., Wang, A. H., Lin, G. S. & Chern, J. W., 5月 15 1994, 於: Acta crystallographica. Section C, Crystal structure communications. 50 ( Pt 5), p. 734-736 3 p.

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1 引文斯高帕斯（Scopus）

5#x02B9;-CGA Motif Induces Other Sequences To Form Homo Base-Paired Parallel-Stranded DNA Duplex: The Structure of (G-A)_n Derived from Four DNA Oligomers Containing (G-A)₃ Sequence

Robinson, H., Wang, A. H. J. & van Boom, J. H., 2月 1 1994, 於: Journal of the American Chemical Society. 116, 4, p. 1565-1566 2 p.

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30 引文斯高帕斯（Scopus）

Conformations of the alternating (C-T)_n sequence under neutral and low pH

Jaishree, T. N. & Wang, A. H. J., 1月 10 1994, 於: FEBS Letters. 337, 2, p. 139-144 6 p.

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7 引文斯高帕斯（Scopus）

Crystal and Solution Structures of d(CGC[e⁶G]AATTCGCG)‐Drug Complexes Reveal Conformational Polymorphism of O⁶‐Ethyl‐Guanine:Cytosine Base Pair

SRIRAM, M., YANG, D., GAO, Y. G. & WANG, ANDREW. H. J., 7月 1994, 於: Annals of the New York Academy of Sciences. 726, 1, p. 18-44 27 p.

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3 引文斯高帕斯（Scopus）

Crystal Structures of Y41H and Y41F Mutants of Gene V Protein from Ff Phage Suggest Possible Protein-Protein Interactions in the GVP-ssDNA Complex

Guan, Y., Zhang, H., Wang, A. H. J., Konings, R. N. H., Hilbers, C. W. & Terwilliger, T. C., 6月 1 1994, 於: Biochemistry. 33, 25, p. 7768-7778 11 p.

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30 引文斯高帕斯（Scopus）

Human chromosomal centromere (AATGG)_n sequence forms stable structures with unusual base pairs

Jaishree, T. N. & Wang, A. H. J., 6月 20 1994, 於: FEBS Letters. 347, 1, p. 99-103 5 p.

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7 引文斯高帕斯（Scopus）

Solution Structure of a GA Mismatch DNA Sequence, d(CCATGAATGG)₂, Determined by 2D NMR and Structural Refinement Methods

Greene, K. L., Jones, R. L., Li, Y., Robinson, H., Wang, A. H. J., Zon, G. & Wilson, W. D., 2月 1 1994, 於: Biochemistry. 33, 5, p. 1053-1062 10 p.

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73 引文斯高帕斯（Scopus）

Structure and dynamics of the antitumor drugs nogalamycin and disnogalamycin complexed to d(CGTACG)₂: comparison of crystal and solution structures

Robinson, H., Yang, D. & Wang, A. H. J., 11月 4 1994, 於: Gene. 149, 1, p. 179-188 10 p.

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10 引文斯高帕斯（Scopus）

Structure by NMR of Antitumor Drugs Aclacinomycin A and B Complexed to dCCGTACG)

Yang, D. & Wang, A. H. J., 5月 1 1994, 於: Biochemistry. 33, 21, p. 6595-6604 10 p.

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34 引文斯高帕斯（Scopus）

Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein

Skinner, M. M., Zhang, H., Leschnitzer, D. H., Guan, Y., Bellamy, H., Sweet, R. M., Gray, C. W., Konings, R. N. H., Wang, A. H. J. & Terwilliger, T. C., 3月 15 1994, 於: Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2071-2075 5 p.

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116 引文斯高帕斯（Scopus）

1993

5′-CGA sequence is a strong motif for homo base-paired parallel-stranded DNA duplex as revealed by NMR analysis

Robinson, H. & Wang, A. H. J., 6月 1 1993, 於: Proceedings of the National Academy of Sciences of the United States of America. 90, 11, p. 5224-5228 5 p.

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60 引文斯高帕斯（Scopus）

Crystallographic studies of metal ion - DNA interactions: Different binding modes of cobalt(II), copper(II) and barium(II) to nof guanines in Z-DNA and a drug-DNA complex

Gao, Y. G., Sriram, M. & Wang, A. H. J., 8月 25 1993, 於: Nucleic Acids Research. 21, 17, p. 4093-4101 9 p.

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127 引文斯高帕斯（Scopus）

Demonstration of Z-d(^5BrCGAT^5BrCG) and B-d(CGCGATCGCG) form crystal stuctures in DNA-cobalt hexammine complexes by Kr 647.1 nm excitation of Raman spectra

Benevides, J. M., Wang, A. H. J. & Thomas, G. J., 3月 25 1993, 於: Nucleic Acids Research. 21, 6, p. 1433-1438 6 p.

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9 引文斯高帕斯（Scopus）

Local Raman Tensors of Double-Helical DNA in the Crystal: A Basis for Determining DNA Residue Orientations

Benevides, J. M., Tsuboi, M., Thomas, G. J. & Wang, A. H. J., 6月 1 1993, 於: Journal of the American Chemical Society. 115, 13, p. 5351-5359 9 p.

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32 引文斯高帕斯（Scopus）

Minor Groove Binding of SN6999 to an Alkylated DNA: Molecular Structure of d(CGC[e⁶G]AATTCGCG)-SN6999 Complex

Gao, Y. G., Sriram, M., Denny, W. A. & Wang, A. H. J., 1993, 於: Biochemistry. 32, 37, p. 9639-9648 10 p.

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29 引文斯高帕斯（Scopus）

Molecular and crystal structures of ecteinascidins: Potent antitumor compounds from the Caribbean tunicate Ecteinascidia turbinata

Guan, Y., Sakai, R., Rinehart, K. L. & Wang, A. H. J., 1993, 於: Journal of Biomolecular Structure and Dynamics. 10, 5, p. 793-818 26 p.

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100 引文斯高帕斯（Scopus）

Molecular structure of cyclic diguanylic acid at 1 Å resolution of iwo crystal forms: Self-association, interactions with metal ion/planar dyes and modeling studies

Guan, Y., Gao, Y. G., Liaw, Y. C., Robinson, H. & Wang, A. H. J., 10月 1993, 於: Journal of Biomolecular Structure and Dynamics. 11, 2, p. 253-276 24 p.

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20 引文斯高帕斯（Scopus）

NMR studies of pH-dependent conformational polymorphism of alternating (C-T)n sequences

Jaishree, T. N. & Wang, A. H. J., 8月 11 1993, 於: Nucleic Acids Research. 21, 16, p. 3839-3844 6 p.

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23 引文斯高帕斯（Scopus）

Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross linked adducts of daunorubicin- d(CG(araC)G0CG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution

Zhang, H., Gao, Y. G., Van der Marel, G. A., Van Boom, J. H. & Wang, A. H. J., 1993, 於: Journal of Biological Chemistry. 268, 14, p. 10095-10101 7 p.

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29 引文斯高帕斯（Scopus）

Structural Effects of the C²-Methylhypoxanthine: Cytosine Base Pair in B-DNA: A Combined NMR and X-ray Diffraction Study of d(CGC[m²I]AATTCGCG)

Yang, D., Gao, Y. G., Robinson, H., Wang, A. H. J., van der Marel, G. A. & van Boom, J. H., 1993, 於: Biochemistry. 32, 33, p. 8672-8681 10 p.

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7 引文斯高帕斯（Scopus）

Structural Influence of RNA Incorporation in DNA: Quantitative Nuclear Magnetic Resonance Refinement of d(CG)r(CG)d(CG) and d(CG)r(C)d(TAGCG)

Jaishree, T. N., Wang, A. H. J., van der Marel, G. A. & van Boom, J. H., 1993, 於: Biochemistry. 32, 18, p. 4903-4911 9 p.

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42 引文斯高帕斯（Scopus）

Studies on 1,2,4-benzothiadiazine 1,1-dioxides VII and quinazolinones IV: Synthesis of novel built-in hydroxyguanidine tricycles as potential anticancer agents

Chern, J. W., Liaw, Y. C., Chen, C. S., Rong, J. G., Huang, C. L., Chan, C. H. & Wang, A. H. J., 5月 1 1993, 於: Heterocycles. 36, 5, p. 1091-1103 13 p.

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26 引文斯高帕斯（Scopus）

Z-DNA Structure of a Modified DNA Hexamer at 1.4-Å Resolution: Aminohexyl- 5′-d(pCpGp [br⁵C] pGpCpG

Jean, Y. C., Gao, Y. G. & Wang, A. H. J., 1月 1 1993, 於: Biochemistry. 32, 1, p. 381-388 8 p.

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16 引文斯高帕斯（Scopus）

1992

Additional antitumor ecteinascidins from a Caribbean tunicate: Crystal structures and activities in vivo

Sakai, R., Rinehart, K. L., Guan, Y. & Wang, A. H. J., 12月 1 1992, 於: Proceedings of the National Academy of Sciences of the United States of America. 89, 23, p. 11456-11460 5 p.

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170 引文斯高帕斯（Scopus）

A Simple Spectral-Driven Procedure for the Refinement of DNA Structures by NMR Spectroscopy

Howard, R. & Andrew, H. J. W., 1992, 於: Biochemistry. 31, 13, p. 3524-3533 10 p.

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53 引文斯高帕斯（Scopus）

Conformational perturbation of the anticancer nucleoside arabinosylcytosine on Z‐DNA: Molecular structure of (araC‐dG)₃ at 1.3 Å resolution

Zhang, H., Van Der Marel, G. A., Van Boom, J. H. & Wang, A. H. J., 11月 1992, 於: Biopolymers. 32, 11, p. 1559-1569 11 p.

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13 引文斯高帕斯（Scopus）

Conformation of B-DNA containing O⁶-ethyl-G-C base pairs stabilized by minor groove binding drugs: Molecular structure of dCGC[e⁶G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342

Sriram, M., Van Der Marel, G. A., Roelen, H. L. P. F., Van Boom, J. H. & Wang, A. H. J., 1992, 於: EMBO Journal. 11, 1, p. 225-232 8 p.

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105 引文斯高帕斯（Scopus）

Heterocyclic compounds. I. Reactions of o-amino-carboxamide with β-diketones: Synthesis of imidazo[1,5-a]pyrimidine and pyrazolo[1,5-a]pyrimidine derivatives

Ji-Wang, C., Chung-Chi, L., Yen-Chywan, L. & Andrew Wang, H. J., 6月 1 1992, 於: Heterocycles. 34, 6, p. 1133-1145 13 p.

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2 引文斯高帕斯（Scopus）

Intercalative drug binding to DNA

Wang, A. H. J., 6月 1992, 於: Current Opinion in Structural Biology. 2, 3, p. 361-368 8 p.

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81 引文斯高帕斯（Scopus）

Molecular structures of two new anti-HIV nucleoside analogs: 9-(2,3-dideoxy-2-fluore-β-d-threopentofuranosyl)adenine and 9-(2,3-dideoxy-2-fluoro-β-d-threo-pentofurancsyl)hypoxanthine

Liaw, Y. C., Gao, Y. G., Marquez, V. E. & Wang, A. H. J., 2月 11 1992, 於: Nucleic Acids Research. 20, 3, p. 459-465 7 p.

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16 引文斯高帕斯（Scopus）

Stereoselective Synthesis Of Ribonucleoside 3’,5’-Cyclic Methyl(Phenyl)Phosphonates And Phosphonothioates

Roelen, H. C. P. F., Vroom, E. D., Der Marel, G. A. V., Boom, J. H. V. & Wang, A. H. J., 1月 1 1992, 於: Nucleosides and Nucleotides. 11, 1, p. 141-156 16 p.

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4 引文斯高帕斯（Scopus）

Structural Consequences of a Carcinogenic Alkylation Lesion on DNA: Effect of O⁶-Ethylguanine on the Molecular Structure of D(Cgc[e⁶G]Aattcgcg)-Netropsin Complex

Sriram, M., Wang, A. H. J., van der Marel, G. A., Roelen, H. L. P. F. & van Boom, J. H., 2月 1 1992, 於: Biochemistry. 31, 47, p. 11823-11834 12 p.

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86 引文斯高帕斯（Scopus）

Unusual conformational flexibility in N¹-substituted uncommon purine nucleosides Crystal structure of 1-allyl-isoguanosine and 1-allyl-xanthosine

Liaw, Y. C., Chern, J. W., Lin, G. S. & Wang, A. H. J., 2月 3 1992, 於: FEBS Letters. 297, 1-2, p. 4-8 5 p.

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6 引文斯高帕斯（Scopus）

Unusual DNA Conformation at Low pH Revealed by NMR: Parallel-Stranded DNA Duplex with Homo Base Pairs

Robinson, H., Wang, A. H. J., van der Marel, G. A. & van Boom, J. H., 2月 1 1992, 於: Biochemistry. 31, 43, p. 10510-10517 8 p.

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87 引文斯高帕斯（Scopus）

1991

Comparison of two hydrated forms of sodium inosine 5'-monophosphate.

Sriram, M., Liaw, Y. C., Gao, Y. G. & Wang, A. H., 3月 15 1991, 於: Acta crystallographica. Section C, Crystal structure communications. 47 ( Pt 3), p. 507-510 4 p.

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18 引文斯高帕斯（Scopus）

Covalent modification of guanine bases in double-stranded DNA: The 1.2-Å Z-DNA structure of d(CGCGCG) in the presence of CuC1₂

Kagawa, T. F., Geierstanger, B. H., Wang, A. H. J. & Shing Ho, P., 1991, 於: Journal of Biological Chemistry. 266, 30, p. 20175-20184 10 p.

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167 引文斯高帕斯（Scopus）

Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: Molecular structure of the MAR70-d(CGTⁿACG) covalent adduct

Gao, Y. G., Liaw, Y. C., Li, Y. K., Van Der Marel, G. A., Van Boom, J. H. & Wang, A. H. J., 6月 1 1991, 於: Proceedings of the National Academy of Sciences of the United States of America. 88, 11, p. 4845-4849 5 p.

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42 引文斯高帕斯（Scopus）

Formaldehyde Cross-Links Daunorubicin and DNA Efficiently: HPLC and X-ray Diffraction Studies

Andrew Wang, H. J., Gao, Y. G., Liaw, Y. C. & Li, Y. K., 4月 1 1991, 於: Biochemistry. 30, 16, p. 3812-3815 4 p.

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127 引文斯高帕斯（Scopus）

Influence of aglycone modifications on the binding of anthracycline drugs to DNA: The molecular structure of idarubicin and 4-O-demethyl-11 deoxydoxorubicin complexed to d(CGATCG)

Gao, Y. G. & Wang, A. H. J., 1991, 於: Anti-Cancer Drug Design. 6, 3, p. 137-149 13 p.

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29 引文斯高帕斯（Scopus）

Interaction between the left-handed Z-DNA and polyamine The crystal structure of the d(CG)₃ and N-(2-aminoethyl)-1,4-diamino-butane complex

Ohishi, H., Kunisawa, S., van der Marel, G., van Boom, J. H., Rich, A., Wang, A. H. J., Tomita, K. I. & Hakoshima, T., 6月 24 1991, 於: FEBS Letters. 284, 2, p. 238-244 7 p.

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29 引文斯高帕斯（Scopus）

Molecular Dynamics Investigation of the Interaction between DNA and Distamycin

Boehncke, K., Nonella, M., Schulten, K. & Wang, A. H. J., 6月 1 1991, 於: Biochemistry. 30, 22, p. 5465-5475 11 p.

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28 引文斯高帕斯（Scopus）

Molecular Structure of a DNA Decamer Containing an Anticancer Nucleoside Arabinosylcytosine: Conformational Perturbation by Arabinosylcytosine in B-DNA

Gao, Y. G., Wang, A. H. J., van der Marel, G. A. & van Boom, J. H., 10月 1 1991, 於: Biochemistry. 30, 41, p. 9922-9931 10 p.

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39 引文斯高帕斯（Scopus）

王 惠鈞

研究成果

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王惠鈞