臺北醫學大學新藥開發研究中心

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• Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

  Lai, M.-J. (Creator), Lee, C.-H. (Creator), Chao, Y.-H. (Creator), Mehndiratta, S. (Creator), Chen, M.-C. (Creator), Liou, J.-P. (Creator) & Lee, H.-Y. (Creator), Taylor & Francis, 2020

  DOI: 10.6084/m9.figshare.13207104.v1, https://tandf.figshare.com/articles/journal_contribution/Effect_of_3-subsitution_of_quinolinehydroxamic_acids_on_selectivity_of_histone_deacetylase_isoforms/13207104/1

  資料集: Dataset

• Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

  Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020

  DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1

  資料集: Dataset

• MOESM2 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Lin, Y.-J. (Creator), Chen, C.-H. (Contributor), Liao, W.-L. (Creator), Wu, J.-Y. (Contributor), Tsai, F.-J. (Contributor), Chang, W.-C. (Contributor), Lu, H.-F. (Contributor) & Wong, H.S.-C. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270436.v1, https://doi.org/10.6084%2Fm9.figshare.10270436.v1

  資料集: Dataset

• Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

  Tsai, I.-T. (Contributor), Kuo, C.-C. (Contributor), Liou, J.-P. (Creator) & Chang, J.-Y. (Contributor), Figshare, 2018

  DOI: 10.6084/m9.figshare.c.4052207.v1, https://figshare.com/collections/Novel_microtubule_inhibitor_MPT0B098_inhibits_hypoxia-induced_epithelial-to-mesenchymal_transition_in_head_and_neck_squamous_cell_carcinoma/4052207/1

  資料集: Dataset

• Ring size changes in the development of class I HDAC inhibitors

  Lee, H.-Y. (Contributor), Cho, E.-C. (Contributor), Tang, D.-W. (Contributor) & Liu, C.-Y. (Contributor), figshare Academic Research System, 1月 1 2021

  DOI: 10.6084/m9.figshare.14843703.v1, https://tandf.figshare.com/articles/journal_contribution/Ring_size_changes_in_the_development_of_class_I_HDAC_inhibitors/14843703/1

  資料集: Dataset

• EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

  Sung, T.-Y. (Creator), Huang, H.-L. (Contributor), Cheng, C.-C. (Creator), Chang, F.-L. (Creator), Wei, P.-L. (Contributor), Cheng, Y.-W. (Creator), Huang, C.-C. (Contributor), Lee, Y.-C. (Contributor), HuangFu, W.-C. (Creator) & Pan, S.-L. (Creator), Figshare, 2021

  DOI: 10.6084/m9.figshare.c.5341486.v1, https://springernature.figshare.com/collections/EGFL6_promotes_colorectal_cancer_cell_growth_and_mobility_and_the_anti_cancer_property_of_anti-EGFL6_antibody/5341486/1

  資料集: Dataset

• MOESM1 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Chen, C.-H. (Contributor), Lin, Y.-J. (Creator), Wu, J.-Y. (Contributor), Liao, W.-L. (Creator), Chang, W.-C. (Contributor), Wong, H.S.-C. (Creator), Lu, H.-F. (Contributor) & Tsai, F.-J. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270427.v1, https://doi.org/10.6084%2Fm9.figshare.10270427.v1

  資料集: Dataset

• Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity

  Chen, C.-Y. (Contributor), Liao, P.-L. (Contributor), Tsai, C.-H. (Contributor), Chan, Y.-J. (Contributor), Cheng, Y.-W. (Creator), Hwang, L.-L. (Creator), Lin, K.-H. (Contributor), Yen, T.-L. (Contributor) & Li, C.-H. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.c.4701761.v1, https://springernature.figshare.com/collections/Inhaled_gold_nanoparticles_cause_cerebral_edema_and_upregulate_endothelial_aquaporin_1_expression_involving_caveolin_1_dependent_repression_of_extracellular_regulated_protein_kinase_activity/4701761/1

  資料集: Dataset

• Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

  Chao, M.-W. (Contributor), Chang, L.-H. (Contributor), Tu, H.-J. (Contributor), Chang, C.-D. (Contributor), Lai, M.-J. (Contributor), Chen, Y.-Y. (Creator), Liou, J.-P. (Creator), Teng, C.-M. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.c.4522856.v1, https://springernature.figshare.com/collections/Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/4522856/1

  資料集: Dataset

• Additional file 1 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation

  Ho, J.-D. (Contributor), Lin, F.-L. (Contributor), Tsai, C.-H. (Contributor), Liao, P.-L. (Contributor), Chan, Y.-J. (Contributor), Cheng, Y.-W. (Creator), Li, C.-H. (Creator) & Chen, C.-Y. (Contributor), Figshare, 2021

  DOI: 10.6084/m9.figshare.13550758.v1, https://doi.org/10.6084%2Fm9.figshare.13550758.v1

  資料集: Dataset

• Additional file 1: Table S1. of The association between BDNF Val66Met polymorphism and emotional symptoms after mild traumatic brain injury

  Wang, Y.-J. (Contributor), Chen, K.-Y. (Contributor), Kuo, L.-N. (Contributor), Wang, W.-C. (Contributor), Hsu, Y.-W. (Contributor), Wong, H. (Contributor), Lin, C.-M. (Contributor), Liao, K.-H. (Contributor), Zhang, Y.-F. (Contributor), Chiang, Y.-H. (Contributor) & Chang, W.-C. (Contributor), Unknown Publisher, 1月 22 2018

  DOI: 10.6084/m9.figshare.5812275.v1, https://springernature.figshare.com/articles/Additional_file_1_Table_S1_of_The_association_between_BDNF_Val66Met_polymorphism_and_emotional_symptoms_after_mild_traumatic_brain_injury/5812275/1

  資料集: Dataset

• Additional file 1: of Suberoylanilide hydroxamic acid represses glioma stem-like cells

  Chang, K.-Y. (Creator), Wang, J.-Y. (Creator), Chuang, J.-Y. (Creator), Ko, C.-Y. (Contributor), Hsu, T.-I. (Contributor), Chang, W.-C. (Creator), Yeh, S.-H. (Contributor), Liou, J.-P. (Creator), Liu, J.-J. (Contributor) & Hsu, C.-C. (Contributor), Figshare, 2016

  DOI: 10.6084/m9.figshare.c.3596465_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3596465_d1.v1

  資料集: Dataset

• Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer

  Cheng, Y.-A. (Creator), Wu, T.-H. (Contributor), Wang, Y.-M. (Contributor), Cheng, T.-L. (Creator), Chen, I.-J. (Creator), Lu, Y.-C. (Contributor), Chuang, K.-H. (Contributor), Wang, C.-K. (Contributor), Chen, C.-Y. (Creator), Lin, R.-A. (Creator), Chen, H.-J. (Creator), Liao, T.-Y. (Contributor), Liu, E.-S. (Contributor) & Chen, F.-M. (Creator), Figshare, 2020

  DOI: 10.6084/m9.figshare.c.5105096.v1, https://springernature.figshare.com/collections/Humanized_bispecific_antibody_mPEG_HER2_rapidly_confers_PEGylated_nanoparticles_tumor_specificity_for_multimodality_imaging_in_breast_cancer/5105096/1

  資料集: Dataset

• MOESM7 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Chou, S.-W. (Creator), Chen, P.-Y. (Contributor), Chu, J.-M. (Contributor), Chien, C.-H. (Contributor), Liu, J.-J. (Creator), Liu, M.-S. (Creator), Chuang, J.-Y. (Creator), Chung, P.-H. (Contributor), Hsu, T.-I. (Contributor), Chen, S.-H. (Contributor), Yang, S.-T. (Creator), Lo, W.-L. (Creator), Huang, C.-Y. (Contributor), Chang, K.-Y. (Contributor), Yang, K.-Y. (Creator) & Yang, W.-B. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006880.v1, https://doi.org/10.6084%2Fm9.figshare.10006880.v1

  資料集: Dataset

• Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation

  Tsai, Y.-T. (Creator), Lo, W.-L. (Creator), Chen, P.-Y. (Creator), Ko, C.-Y. (Creator), Chuang, J.-Y. (Creator), Kao, T.-J. (Creator), Yang, W.-B. (Creator), Chang, K.-Y. (Creator), Hung, C.-Y. (Creator), Kikkawa, U. (Creator), Chang, W.-C. (Creator) & Hsu, T.-I. (Creator), Figshare, 2022

  DOI: 10.6084/m9.figshare.c.5916320.v1, https://springernature.figshare.com/collections/Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/5916320/1

  資料集: Dataset

• MOESM11 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Lu, H.-F. (Contributor), Wong, H.S.-C. (Creator), Lin, Y.-J. (Creator), Liao, W.-L. (Creator), Wu, J.-Y. (Contributor), Chang, W.-C. (Contributor), Tsai, F.-J. (Contributor) & Chen, C.-H. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270418.v1, https://doi.org/10.6084%2Fm9.figshare.10270418.v1

  資料集: Dataset

• MOESM3 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Liao, W.-L. (Creator), Chang, W.-C. (Contributor), Wu, J.-Y. (Contributor), Tsai, F.-J. (Contributor), Lin, Y.-J. (Creator), Wong, H.S.-C. (Creator), Chen, C.-H. (Contributor) & Lu, H.-F. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270439.v1, https://doi.org/10.6084%2Fm9.figshare.10270439.v1

  資料集: Dataset

• Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

  Kao, C.-C. (Contributor), Cheng, S.-Y. (Creator), Wang, Y.-J. (Creator), Chien, S.-C. (Creator), Hsu, Y.-W. (Creator), Wu, M.-Y. (Creator), Lu, H.-F. (Contributor), Nam, S. (Creator), Sun, T. (Creator), Wu, M.-S. (Creator) & Chang, W.-C. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.c.4531100.v1, https://doi.org/10.6084%2Fm9.figshare.c.4531100.v1

  資料集: Dataset

• Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors

  Chen, L.-C. (Contributor), Lin, S.-Y. (Contributor), Sheu, M.-T. (Contributor), Ho, Y.-S. (Contributor), Su, C.-Y. (Contributor), Chen, M. (Contributor), Ho, H.-O. (Contributor) & Chuang, K.-H. (Contributor), Unknown Publisher, 2018

  DOI: 10.6084/m9.figshare.6213620, https://doi.org/10.6084%2Fm9.figshare.6213620

  資料集: Dataset

• Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

  Hsieh, C.-M. (Contributor), Chen, L.-C. (Contributor), Liu, D.-Z. (Contributor), Ho, H.-O. (Contributor), Su, C.-Y. (Contributor), Sheu, M.-T. (Contributor), Jhan, H.-J. (Contributor) & Chang, C.-E. (Contributor), Unknown Publisher, 2018

  DOI: 10.6084/m9.figshare.5908795, https://doi.org/10.6084%2Fm9.figshare.5908795

  資料集: Dataset

• Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

  Lin, C.-F. (Creator), Hsu, K.-C. (Creator), Huangfu, W.-C. (Contributor), Lin, T. E. (Creator), Huang, H.-L. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2020

  DOI: 10.6084/m9.figshare.c.4896705.v1, https://springernature.figshare.com/collections/Investigating_the_potential_effects_of_selective_histone_deacetylase_6_inhibitor_ACY1215_on_infarct_size_in_rats_with_cardiac_ischemia-reperfusion_injury/4896705/1

  資料集: Dataset

• Additional file 1: of The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells

  Tu, H.-J. (Contributor), Lin, Y.-J. (Contributor), Chao, M.-W. (Contributor), Sung, T.-Y. (Contributor), Wu, Y.-W. (Contributor), Chen, Y.-Y. (Contributor), Lin, M.-H. (Contributor), Liou, J.-P. (Contributor), Pan, S.-L. (Contributor) & Yang, C.-R. (Contributor), Unknown Publisher, 12月 29 2018

  DOI: 10.6084/m9.figshare.7531874.v1, https://springernature.figshare.com/articles/Additional_file_1_of_The_anticancer_effects_of_MPT0G211_a_novel_HDAC6_inhibitor_combined_with_chemotherapeutic_agents_in_human_acute_leukemia_cells/7531874/1

  資料集: Dataset

• MOESM6 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Liao, W.-L. (Creator), Tsai, F.-J. (Contributor), Lin, Y.-J. (Creator), Wong, H.S.-C. (Creator), Chang, W.-C. (Contributor), Chen, C.-H. (Contributor), Lu, H.-F. (Contributor) & Wu, J.-Y. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270454.v1, https://doi.org/10.6084%2Fm9.figshare.10270454.v1

  資料集: Dataset

• Additional file 3 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

  HuangFu, W.-C. (Creator), Sung, T.-Y. (Creator), Lee, Y.-C. (Contributor), Pan, S.-L. (Creator), Cheng, Y.-W. (Creator), Chang, F.-L. (Creator), Wei, P.-L. (Contributor), Huang, C.-C. (Contributor), Huang, H.-L. (Contributor) & Cheng, C.-C. (Creator), Figshare, 2021

  DOI: 10.6084/m9.figshare.14228284.v1, https://doi.org/10.6084%2Fm9.figshare.14228284.v1

  資料集: Dataset

• The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells

  Tu, H.-J. (Contributor), Lin, Y.-J. (Contributor), Chao, M.-W. (Contributor), Sung, T.-Y. (Creator), Wu, Y.-W. (Creator), Chen, Y.-Y. (Creator), Lin, M.-H. (Contributor), Liou, J.-P. (Creator), Pan, S.-L. (Contributor) & Yang, C.-R. (Contributor), Figshare, 2018

  DOI: 10.6084/m9.figshare.c.4350887.v1, https://springernature.figshare.com/collections/The_anticancer_effects_of_MPT0G211_a_novel_HDAC6_inhibitor_combined_with_chemotherapeutic_agents_in_human_acute_leukemia_cells/4350887/1

  資料集: Dataset