臺北醫學大學癌症轉譯研究中心

2025

A comparative analysis of Marburg virus-infected bat and human models from public high-throughput sequencing data

Xuan, D. T. M., Yeh, I. J., Liu, H. L., Su, C. Y., Ko, C. C., Ta, H. D. K., Jiang, J. Z., Sun, Z., Lin, H. Y., Wang, C. Y. & Yen, M. C., 2025, 於: International Journal of Medical Sciences. 22, 1, p. 55-70 16 p.

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A real-world study to evaluate effectiveness of mepolizumab in treating severe asthma in Taiwan (REMIT)

Cheng, S. L., Lin, S. M., Peng, C. K., Chan, M. C., Shen, S. Y., Kuo, P. H., Lai, C. H., Lan, C. C., Chen, C. Y., Lin, C. H., Liao, K. M., Feng, P. H., Wu, J. T., Wei, Y. F., Xu, X., Alfonso-Christancho, R., Lai, T., Navarro, A., Milea, D. & Perng, D. W., 1月 1 2025, 於: Therapeutic Advances in Respiratory Disease. 19, p. 17534666241308406

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Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT): an international, multicentre, phase 3, randomised, double-blind, placebo-controlled trial

Chia, J. W. K., Segelov, E., Deng, Y., Ho, G. F., Wang, W., Han, S., Sharma, A., Ding, K., Chen, G., Jeffery, M. G., Tham, C. K., Ahn, J. B., Nott, L., Zielinski, R., Chao, T.-Y., van Hagen, T., Wei, P.-L., Day, F., Mehta, S. & Yau, T. 及其他10, Peng, J., Hayes, T. M., Li, Y., Gandhi, M., Foo, E. M. J., Rahman, N., Rothwell, P., Ali, R., Simes, J. & Toh, H. C., 3月 2025, 於: The Lancet Gastroenterology and Hepatology. 10, 3, p. 198-209 12 p.

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1 引文斯高帕斯（Scopus）

CXCR4 antagonist-loaded nanoparticles reprogram the tumor microenvironment and enhance immunotherapy in hepatocellular carcinoma

Cheng, S. L., Wu, C. H., Tsai, Y. J., Song, J. S., Chen, H. M., Yeh, T. K., Shen, C. T., Chiang, J. C., Lee, H. M., Huang, K. W., Chen, Y., Qiu, J. T., Yen, Y. T., Shia, K. S. & Chen, Y., 3月 10 2025, 於: Journal of Controlled Release. 379, p. 967-981 15 p.

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Development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection

Banerjee, S., Hsu, Y. T., Nguyen, D. H., Yeh, S. H., Liou, K. C., Liu, J. J., Liou, J. P. & Chuang, J. Y., 2月 2025, 於: Biomedicine and Pharmacotherapy. 183, 117851.

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Durvalumab, Tremelimumab, and Platinum Chemotherapy in EGFR Mutation–Positive NSCLC: An Open-Label Phase 2 Trial (ILLUMINATE)

Lee, C. K., Liao, B. C., Subramaniam, S., Chiu, C. H., Mersiades, A. J., Ho, C. C., Brown, C., Lai, C. L., Hughes, B. G. M., Yang, T. Y., O'Byrne, K., Luo, Y. H., Yip, S., Ho, C. L., Bray, V., Su, W. C., Moore, M., Feng, W. L., Bai, Y. Y. & Ford, K. 及其他5, Cummins, M. M., Stockler, M. R., Solomon, B. J., John, T. & Chih-Hsin Yang, J., 2月 2025, 於: JTO Clinical and Research Reports. 6, 2, 100771.

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Effectiveness of pudendal nerve block in the management of acute post-haemorrhoidectomy pain in Asian individuals using inverse probability of treatment weighting (IPTW)

Chen, C. C., Chang, K. T., Lee, Y. W., Chen, J. S., Wei, P. L., Chang, C. L. & Huang, Y. J., 1月 2025, 於: Asian Journal of Surgery. 48, 1, p. 131-136 6 p.

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Effects of photobiomodulation therapy for acute radiation dermatitis in patients with cancer: A systematic review and meta‑analysis of real-world evidence

Lin, Y. T., Mou Tung, K., Chiou, J. F., Chen, Y. C. & Hou, W. H., 1月 2025, 於: Radiotherapy and Oncology. 202, 110589.

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Heteronemin suppresses EGF‑induced proliferation through the PI3K/PD‑L1 signaling pathways in cholangiocarcinoma

Yang, Y. C. S. H., Tsai, C. C., Yang, Y. N., Liu, F. C., Lee, S. Y., Yang, J. C., Crawford, D. R., Chiu, H. C., Lu, M. C., Li, Z. L., Chen, Y. C., Chu, T. Y., Whang-Peng, J., Lin, H. Y. & Wang, K., 3月 2025, 於: Oncology Reports. 53, 3, 32.

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Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients

Cheng, T.-C., Hung, M.-C., Wang, L.-H., Tu, S.-H., Wu, C.-H., Yen, Y., Chen, C.-L., Whang-Peng, J., Lee, W.-J., Liao, Y.-C., Lee, Y.-C., Pan, M.-H., Lin, H.-K., Tzeng, H.-E., Guo, P., Chu, C.-Y. & Chen, L.-C., 1月 9 2025, 於: Biomarker Research. 13, 1, p. 7

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Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients

Cheng, T. C., Hung, M. C., Wang, L. H., Tu, S.-H., Wu, C.-H., Yen, Y., Chen, C. L., Whang-Peng, J., Lee, W. J., Liao, Y. C., Lee, Y.-C., Pan, M. H., Lin, H. K., Tzeng, H.-E., Guo, P., Chu, C.-Y., Chen, L. C. & Ho, Y.-S., 12月 2025, 於: Biomarker Research. 13, 1, 7.

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Hypoxia enhances IL-8 signaling through inhibiting miR-128-3p expression in glioblastomas

Ho, K. H., Hsu, S. Y., Chen, P. H., Cheng, C. H., Liu, A. J., Chien, M. H. & Chen, K. C., 2月 2025, 於: Biochimica et Biophysica Acta - Molecular Cell Research. 1872, 2, 119885.

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Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening

Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., 1月 13 2025, 於: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.

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Machine Learning Approach to Identifying Wrong-Site Surgeries Using Centers for Medicare and Medicaid Services Dataset: Development and Validation Study

Chen, Y.-H., Lin, C.-H., Fan, C.-H., Long, A. J., Scholl, J., Kao, Y.-P., Iqbal, U. & Li, Y.-C. J., 2月 13 2025, 於: JMIR Formative Research. 9, p. e68436

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Molecular characterizations of nanodiamond and related carbon-based nanomaterials in the human cell line and zebrafish models

Li, M., Chang, C., Yeh, T. Y., Lee, T. Y., Lee, K. C. & Cho, E. C., 2月 2025, 於: Diamond and Related Materials. 152, 111946.

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Prognostic utility of neutrophil gelatinase-associated lipocalin (NGAL) levels for cardiovascular events in patients with stable coronary artery disease treated with percutaneous coronary intervention: a prospective longitudinal cohort study

Lin, T. Y., Leu, H. B., Wu, Y. W., Tseng, W. K., Lin, T. H., Yeh, H. I., Chang, K. C., Wang, J. H., Yin, W. H., Wu, C. C., Huang, C. Y., Lin, S. J., Hsu, C. Y. & Chen, J. W., 12月 2025, 於: Biomarker Research. 13, 1, 24.

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Quantifying cell divisions along evolutionary lineages in cancer

Blohmer, M., Cheek, D. M., Hung, W. T., Kessler, M., Chatzidimitriou, F., Wang, J., Hung, W., Lee, I. H., Gorelick, A. N., Wassenaar, E. C. E., Yang, C. Y., Yeh, Y. C., Ho, H. L., Speiser, D., Karsten, M. M., Lanuti, M., Pai, S. I., Kranenburg, O., Lennerz, J. K. & Chou, T. Y. 及其他2, Kloor, M. & Naxerova, K., 2025, (接受/付印) 於: Nature Genetics. 1035.

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1 引文斯高帕斯（Scopus）

Repurposing Linezolid in Conjunction with Histone Deacetylase Inhibitor Access in the Realm of Glioblastoma Therapies

Chen, I. C., Lin, H. Y., Liu, Z. Y., Cheng, W. J., Yeh, T. Y., Yang, W. B., Tran, H. Y., Lai, M. J., Wang, C. H., Kao, T. Y., Hung, C. Y., Huang, Y. L., Liou, K. C., Hsieh, C. M., Hsu, T. I. & Liou, J. P., 2025, 於: Journal of Medicinal Chemistry. 68, 3, p. 2779-2803 25 p.

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Small Extracellular Vesicles Engineered Using Click Chemistry to Express Chimeric Antigen Receptors Show Enhanced Efficacy in Acute Liver Failure

Lu, Y. T., Chen, T. Y., Lin, H. H., Chen, Y. W., Lin, Y. X., Le, D., Huang, Y.-H., Wang, A. H. J., Lee, C.-C. & Ling, T. Y., 2月 2025, 於: Journal of Extracellular Vesicles. 14, 2, e70044.

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The off‑target effect of loratadine triggers autophagy‑mediated apoptosis in lung adenocarcinoma cells by deactivating JNK, p38, and STAT3 signaling through both PP2A‑dependent and independent pathways

Chien, M. H., Hung, W. Y., Lai, T. C., Tsai, C. H., Lee, K. L., Hsieh, F. K., Lee, W. J. & Chang, J. H., 4月 2025, 於: International Journal of Molecular Medicine. 55, 4

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Treadmill intervention attenuates motor deficit with 6-OHDA- induced Parkinson's disease rat via changes in lipid profiles in brain and muscle

Panunggal, B., Yeh, T. H., Tsao, S. P., Pan, C. H., Shih, W. T., Lin, Y. T., Faradina, A., Fang, C. L., Huang, H. Y. & Huang, S. Y., 2025, 於: Aging. 17, 1, p. 232-250 19 p.

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2024

2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside–stimulated dental pulp stem cells-derived exosomes for wound healing and bone regeneration

Lin, T. Y., Huang, T. Y., Chiu, H. C., Chung, Y. Y., Lin, W. C., Lin, H. Y. & Lee, S. Y., 2024, (接受/付印) 於: Journal of Dental Sciences. 20, 1, p. 154-163 10 p.

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Anatomical variations in 3D imaging: A case report of a dorsal metacarpal artery anomaly

Chen, S. Y., Chen, W. T., Fong, T. H., Horng, J. L., Chu, C. Y., Yang, H. & Yang, T. C., 11月 30 2024, 於: Heliyon. 10, 22, e40106.

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1 引文斯高帕斯（Scopus）

An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors

Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., 6月 2024, 於: Protein Science. 33, 6, e5007.

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2 引文斯高帕斯（Scopus）

A new potential therapeutic approach for ALS: A case report with NGS analysis

Hu, C. J., Chen, P. C., Padmanabhan, N., Zahn, A., Ho, C. M., Wang, K. & Yen, Y., 3月 1 2024, 於: Medicine (United States). 103, 9, p. E37401

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1 引文斯高帕斯（Scopus）

An Infant-Type Hemispheric Glioma With SOX5::ALK: A Novel Fusion

Tsai, C. C., Huang, M. H., Fang, C. L., Hsieh, K. L. C., Hsieh, T. H., Ho, W. L., Chang, H., Tsai, M. L., Kao, Y. C., Miser, J. S., Su, M. Y., Wong, T. T. & Liu, Y. L., 2月 2024, 於: JNCCN Journal of the National Comprehensive Cancer Network. 22, 1

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1 引文斯高帕斯（Scopus）

An investigation into the cognitive flexibility of undergraduate dental hygiene students at two dental schools in Asia

Liao, S. R., Seki, N., Foxton, R., Sireerat, K., Akiyama, M., Kanamori, Y., Moross, J., Shinada, K., Chen, S. L. S. & Morio, I., 2024, (接受/付印) 於: Journal of Dental Sciences. 19, 4, p. 2196-2202 7 p.

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A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress

Wu, L. H., Cheng, Y. W., Lin, F. L., Hsu, K. C., Wang, M. H., Yen, J. L., Wang, T. J., Lin, T. E., Liu, Y. C., Huang, W. J. & Hsiao, G., 5月 2024, 於: Biomedicine and Pharmacotherapy. 174, 116538.

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2 引文斯高帕斯（Scopus）

A prospective reappraisal of motor outcome prediction in patients with acute stroke by using atlas-based diffusion tensor imaging biomarkers

Chen, Y.-C., Cheng, S.-J., Hsieh, L.-C., Shyu, H.-Y., Chen, M.-H., Chen, C.-Y. & Kuo, D.-P., 3月 2024, 於: Topics in Stroke Rehabilitation. 31, 2, p. 199-210 12 p.

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A Report and Proposals for Future Activity from the Inaugural Artificial Intelligence in Dermatology Symposium Held at the International Societies for Investigative Dermatology 2023 Meeting

Wongvibulsin, S., Sangers, T., Clibborn, C., Li, Y.-C. J., Sharma, N., Common, J. E. A., Reynolds, N. J. & Tanaka, R. J., 1月 2024, 於: JID Innovations. 4, 1, p. 100236

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1 引文斯高帕斯（Scopus）

Arginine Methylation of DDX3 by PRMT1 Mediates Mitochondrial Homeostasis to Promote Breast Cancer Metastasis

Hsu, W. J., Chiang, M. C., Chao, Y. C., Chang, Y. C., Hsu, M. C., Chung, C. H., Tsai, I. L., Chu, C. Y., Wu, H. C., Yang, C. C., Lee, C. C. & Lin, C. W., 9月 15 2024, 於: Cancer Research. 84, 18, p. 3023-3043 21 p.

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ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells

Chan, T. S., Cheng, L. H., Hsu, C. C., Yang, P. M., Liao, T. Y., Hsieh, H. Y., Lin, P. C., HuangFu, W. C., Chuu, C. P. & Tsai, K. K., 2024, (接受/付印) 於: Molecular Oncology. 18, 3, p. 562-579 18 p.

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4 引文斯高帕斯（Scopus）

Assessing Excess Mortality of Baby Boomers from the COVID-19 Pandemic: Taiwan Omicron-naïve Cohort

Lin, T. Y., Hsu, C. Y., Yen, A. M. F., Chen, S. L. S. & Chen, T. H. H., 2024, (接受/付印) 於: Journal of Epidemiology and Global Health. 14, 3, p. 1113-1121 9 p.

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Atrophy of the cholinergic regions advances from early to late mild cognitive impairment

Lai, Y. L. L., Hsu, F. T., Yeh, S. Y., Kuo, Y. T., Lin, H. H., Lin, Y. C., Kuo, L. W., Chen, C. Y. & Liu, H. S., 2024, (接受/付印) 於: Neuroradiology. 66, 4, p. 543-556 14 p.

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1 引文斯高帕斯（Scopus）

A tumor on a chip for studying immune-cell infiltration into tumor under chemo/immunotherapy treatments

Chen, Y. C., Lee, K. Y., Liao, H. J., Sun, W. L., Huang, W. C., Wang, Y. S., Chang, W. C. & Liu, C. H., 5月 1 2024, 於: Sensors and Actuators B: Chemical. 406, 135409.

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6 引文斯高帕斯（Scopus）

B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis

Hsu, T. H., Chang, Y. C., Lee, Y. Y., Chen, C. L., Hsiao, M., Lin, F. R., Chen, L. H., Lin, C. H., Angata, T., Liu, F. T. & Lin, K. I., 9月 2024, 於: Cell Death and Disease. 15, 9, 654.

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Beneficial carry-over effects of chronic at-home genital nerve stimulation on incontinence in individuals with spinal cord injury: A pragmatic trial

Yeh, S. D., Khasanah, N., Gustafson, K. J., Sun, C., Tsai, M. L., Lin, B. S., Wu, C. W. & Peng, C. W., 3月 2024, 於: Annals of Physical and Rehabilitation Medicine. 67, 2, 101799.

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1 引文斯高帕斯（Scopus）

Binding of interleukin-1 receptor antagonist to cholinergic receptor muscarinic 4 promotes immunosuppression and neuroendocrine differentiation in prostate cancer

Liu, Y. N., Liu, M. K., Wen, Y. C., Li, C. H., Yeh, H. L., Dung, P. V. T., Jiang, K. C., Chen, W. H., Li, H. R., Huang, J. & Chen, W. Y., 8月 28 2024, 於: Cancer Letters. 598, 217090.

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2 引文斯高帕斯（Scopus）

Can large language models provide secondary reliable opinion on treatment options for dermatological diseases?

Iqbal, U., Lee, L. T. J., Rahmanti, A. R., Celi, L. A. & Li, Y. C. J., 6月 1 2024, 於: Journal of the American Medical Informatics Association. 31, 6, p. 1341-1347 7 p.

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4 引文斯高帕斯（Scopus）

CCN1 Is a Therapeutic Target for Reperfused Ischemic Brain Injury

Lee, G. A., Chang, Y. W., Lai, J. H., Chang, T. H., Huang, S. W., Yang, C., Shen, T. A., Lin, W. L., Wu, Y. C., Tseng, L. W., Tseng, S. H., Chen, Y. C., Chiang, Y. H. & Chen, C. Y., 2024, (接受/付印) 於: Translational Stroke Research.

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Celecoxib attenuates interleukin 33-induced expression of vascular cell adhesion molecule-1 in human ovarian endometriotic stromal cells

Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 3月 2024, 於: Taiwanese Journal of Obstetrics and Gynecology. 63, 2, p. 178-185 8 p.

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1 引文斯高帕斯（Scopus）

Cerebrospinal Fluid Proteome Map Reveals Molecular Signatures of Reversible Cerebral Vasoconstriction Syndrome

Yang, J. C., Chen, S. P., Wang, Y. F., Chang, C. H., Chang, K. H., Fuh, J. L., Chow, L. H., Han, C. L., Chen, Y. J. & Wang, S. J., 7月 1 2024, 於: Molecular & cellular proteomics : MCP. 23, 7, p. 100794 1 p.

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Characterization of primary Sjögren's syndrome in the Taiwan Han population through a genome-wide association study and polygenic risk score analysis

Liu, T. Y., Lin, M. R., Lu, H. F., Chen, Y. C., Lin, H. J., Chou, W. H., Wei, C. Y., Palupi, P. D., Liao, C. C., Chang, Y. T., Chang, W. C. & Tsai, F. J., 12月 2024, 於: Clinical Immunology. 269, 110381.

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1 引文斯高帕斯（Scopus）

Characterization of the genetic variation and evolutionary divergence of the CLEC18 family

Chang, C. M., Chang, W. C. & Hsieh, S., 12月 2024, 於: Journal of Biomedical Science. 31, 1, 53.

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Comparing Right-sided Colon Adenoma and Serrated Polyp Miss Rates with Water Exchange and CO₂Insufflation: A Randomized Controlled Trial

Cheng, C. L., Tang, J. H., Hsieh, Y. H., Kuo, Y. L., Fang, K.-C., Tseng, C. W., Su, I.-C., Chang, C.-C., Tsui, Y. N., Lee, B. P., Zou, K. Y., Lee, Y. S. & Leung, F. W., 2024, (接受/付印) 於: American Journal of Gastroenterology. 10.14309/ajg.0000000000003168.

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Construction of dual Z-scheme Ag₃VO₄–BiVO₄/InVO₄ photocatalysts using vanadium source from spent catalysts for contaminated water treatment and bacterial inactivation

Lee, K. C., Hsu, S. C., Huang, J. H., Wang, K. S., Pang, W. K., Hu, C. W., Jiang, Y. J., Cho, E. C., Weng, H. C. & Liu, T. Y., 9月 2024, 於: Chemosphere. 363, 142746.

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Cost-effectiveness analysis of pembrolizumab with chemotherapy for metastatic nonsquamous non-small cell lung cancer in Taiwan

Lee, W.-L., Chou, W.-H., Chang, W.-P., Chang, T.-W., Kuo, C.-N. & Chang, W.-C., 12月 15 2024, 於: Journal of Food and Drug Analysis. 32, 4, p. 568-576 9 p., 14.

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Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells

Park, J. M., Su, Y. H., Fan, C. S., Chen, H. H., Qiu, Y. K., Chen, L. L., Chen, H. A., Ramasamy, T. S., Chang, J. S., Huang, S. Y., Chang, W. S. W., Lee, A. Y. L., Huang, T. S., Kuo, C. C. & Chiu, C. F., 9月 2024, 於: Experimental and Molecular Medicine. 56, 9, p. 2065-2081 17 p.

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Crystal structure-controlled synthesis of NiMoO₄/NiO hierarchical microspheres for high-performance supercapacitors and photocatalysts

Lee, K. C., Huang, J. H., Wu, Y. J., Wang, K. S., Cho, E. C., Hsu, S. C. & Liu, T. Y., 9月 1 2024, 於: Journal of Energy Storage. 97, 112639.

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CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity

Liu, C. C., Yang, W. B., Chien, C. H., Wu, C. L., Chuang, J. Y., Chen, P. Y., Chu, J. M., Cheng, S. M., Qiu, L. Y., Chang, Y. C., Hwang, D. Y., Huang, C. Y., Lee, J. S. & Chang, K. Y., 6月 2024, 於: Cell Death and Disease. 15, 6, 434.

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3 引文斯高帕斯（Scopus）

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