臺北醫學大學癌症轉譯研究中心

2023

Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer

Lee, K.-L., Lai, T. C., Lee, W.-J., Chen, Y.-C., Ho, K.-H., Hung, W.-Y., Yang, Y.-C., Chan, M.-H., Hsieh, F.-K., Chung, C.-L., Chang, J.-H. & Chien, M.-H., 6月 22 2023, 於: Cancers. 15, 13

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2 引文斯高帕斯（Scopus）

Sweet: a single-sample network inference method for deciphering individual features in disease

Chen, H.-H., Hsueh, C.-W., Lee, C.-H., Hao, T.-Y., Tu, T.-Y., Chang, L.-Y., Lee, J.-C. & Lin, C.-Y., 1月 2023, (打印前電子出版) 於: Briefings in Bioinformatics.

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9 引文斯高帕斯（Scopus）

Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer

Liu, Y. H., Chen, L. C., Cheng, W. T., Wei, P. S., Hsieh, C. M., Sheu, M. T., Lin, S. Y., Ho, H. O. & Lin, H. L., 2月 2023, 於: Pharmaceutics. 15, 2, 473.

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1 引文斯高帕斯（Scopus）

Synergistic disruption of BTK and BCL-2 causes apoptosis while inducing ferroptosis in double-hit lymphoma

Setiawan, S. A., Liu, W. Z., Weng, P. W., Lee, C. H., Yadav, V. K., Hardianti, M. S., Yeh, C. T. & Chao, T. Y., 3月 15 2023, 於: European Journal of Pharmacology. 943, 175526.

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12 引文斯高帕斯（Scopus）

Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities

Chu, J. C., Tseng, H. J., Lee, S. B., Hsu, K. C., Hsin, L. W., Liang, R. H., Lin, T. E., Gao, N. C., Chen, L. C., Lu, W. H., Wang, A. H. J. & Huang, W. J., 2023, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 38, 1, 2212326.

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Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol

Lee, S., Chao, M. W., Wu, Y. W., Hsu, C. M., Lin, T. E., Hsu, K. C., Pan, S. L. & Lee, H. Y., 10月 30 2023, 於: RSC Advances. 13, 45, p. 31595-31601 7 p.

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Synthesis and Structure–Activity Relationship of Salvinal Derivatives as Potent Microtubule Inhibitors

Chang, C. I., Hsieh, C. C., Wein, Y. S., Kuo, C. C., Chang, C. Y., Lung, J., Cherng, J. Y., Chu, P. C., Chang, J. Y. & Kuo, Y. H., 4月 2023, 於: International journal of molecular sciences. 24, 7, 6386.

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Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor

Giang, L. H., Wu, K. S., Lee, W. C., Chu, S. S., Do, A. D., Changou, C. A., Tran, H. M., Hsieh, T. H., Chen, H. H., Hsieh, C. L., Sung, S. Y., Yu, A. L., Yen, Y., Wong, T. T. & Chang, C. C., 12月 2023, 於: Journal of Experimental and Clinical Cancer Research. 42, 1, 346.

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1 引文斯高帕斯（Scopus）

Targeting PKLR/MYCN/ROMO1 signaling suppresses neuroendocrine differentiation of castration-resistant prostate cancer

Chen, W. Y., Thuy Dung, P. V., Yeh, H. L., Chen, W. H., Jiang, K. C., Li, H. R., Chen, Z. Q., Hsiao, M., Huang, J., Wen, Y. C. & Liu, Y. N., 6月 2023, 於: Redox Biology. 62, 102686.

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6 引文斯高帕斯（Scopus）

Tea consumption and the risks of osteoporosis and hip fracture: a population-based longitudinal follow-up study

Huang, Y.-P., Chen, L. S., Feng, S. H., Liang, Y. S. & Pan, S. L., 1月 2023, 於: Osteoporosis International. 34, 1, p. 101-109 9 p.

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8 引文斯高帕斯（Scopus）

Thalamocortical Coherence Predicts Persistent Postconcussive Symptoms

Li, Y.-T., Kuo, D.-P., Tseng, P., Chen, Y.-C., Cheng, S.-J., Wu, C. W., Hsieh, L.-C., Chiang, Y.-H., Chung, H.-W., Lui, Y. W. & Chen, C.-Y., 7月 2023, 於: Progress in Neurobiology. 226, p. 102464 102464.

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1 引文斯高帕斯（Scopus）

The activation of EP300 by F11R leads to EMT and acts as a prognostic factor in triple-negative breast cancers

Li, C.-H., Fang, C.-Y., Chan, M.-H., Lu, P.-J., Ger, L.-P., Chu, J.-S., Chang, Y.-C., Chen, C.-L. & Hsiao, M., 2023, 於: The Journal of Pathology: Clinical Research. n/a, n/a, 1 p.

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3 引文斯高帕斯（Scopus）

The ADAM9/WISP-1 axis cooperates with osteoblasts to stimulate primary prostate tumor growth and metastasis

Chang, A. C., Lin, L. W., Chen, Y. C., Chen, P. C., Liu, S. C., Tai, H. C., Wu, H. C., Sung, S. Y., Lin, T. H. & Tang, C. H., 2023, 於: International Journal of Biological Sciences. 19, 3, p. 760-771 12 p.

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5 引文斯高帕斯（Scopus）

The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer

Chiang, Y. F., Huang, K. C., Chen, H. Y., Huang, T. C., Ali, M., Chang, H. Y., Shieh, T. M., Shih, Y. H., Wang, K. L., Huang, Y. J., Chung, C. P. & Hsia, S. M., 2月 2023, 於: Biomedicines. 11, 2, 297.

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3 引文斯高帕斯（Scopus）

The Blockade of Mitogen-Activated Protein Kinase 14 Activation by Marine Natural Product Crassolide Triggers ICD in Tumor Cells and Stimulates Anti-Tumor Immunity

Tsai, K. C., Chen, C. S., Su, J. H., Lee, Y. C., Tseng, Y. H. & Wei, W. C., 4月 2023, 於: Marine Drugs. 21, 4, 225.

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2 引文斯高帕斯（Scopus）

The challenging imaging and histopathologic features of diffusely infiltrating breast cancer

Tabár, L., Dean, P. B., Lee Tucker, F., Puchkova, O., Bozó, R., Ming-Fang Yen, A., Li-Sheng Chen, S., Smith, R. A., Duffy, S. W. & Hsiu-Hsi Chen, T., 4月 2023, 於: European Journal of Radiology. 161, 110754.

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9 引文斯高帕斯（Scopus）

The complex role of eicosanoids in the brain: Implications for brain tumor development and therapeutic opportunities

Chen, H. C., Chang, W. C., Chuang, J. Y., Chang, K. Y., Liou, J. P. & Hsu, T. I., 9月 2023, 於: Biochimica et Biophysica Acta - Reviews on Cancer. 1878, 5, 188957.

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2 引文斯高帕斯（Scopus）

The impact of active community-based survey on dementia detection ratio in Taiwan: A cohort study with historical control

Lu, Y. R., Wu, T. H., Jeng, Y., Lee, W. Y., Hsu, W. C., Yen, A. M. F., Pan, S. L., Chen, Y. C., Chen, S. L. S., Chen, H. H. & Liou, H. H., 1月 2023, 於: Frontiers in Public Health. 10, 1005252.

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2 引文斯高帕斯（Scopus）

The Intra-Hospital Medical Dispute Burden and Capacities: A Nationwide Survey in Taiwan

Chia, W. C., Chen, L. S. & Wang, S. T., 8月 2023, 於: Healthcare (Switzerland). 11, 15, 2121.

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Therapeutic potential of EGFR/mTOR/Nf-kb targeting small molecule for the treatment of non-small cell lung cancer

Lawal, B., Kuo, Y.-C., Wu, A. T. & Huang, H.-S., 1月 2023, 於: American Journal of Cancer Research. 13, 6, p. 2598-2616 19 p.

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The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase

Yang, Y. C., Lin, Y. W., Lee, W. J., Lai, F. R., Ho, K. H., Chu, C. Y., Hua, K. T., Chen, J. Q., Tung, M. C., Hsiao, M., Wen, Y. C. & Chien, M. H., 12月 2023, 於: Journal of Biomedical Science. 30, 1, 68.

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6 引文斯高帕斯（Scopus）

The Role of Thrombomodulin in Estrogen-Receptor-Positive Breast Cancer Progression, Metastasis, and Curcumin Sensitivity

Huang, C.-Y., Wei, P.-L., Prince, G. M. S. H., Batzorig, U., Lee, C.-C., Chang, Y.-J. & Hung, C.-S., 5月 7 2023, 於: Biomedicines. 11, 5

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5 引文斯高帕斯（Scopus）

The study of a novel CDK8 inhibitor E966-0530–45418 that inhibits prostate cancer metastasis in vitro and in vivo

Ho, T. Y., Sung, T. Y., Pan, S. L., Huang, W. J., Hsu, K. C., Hsu, J. Y., Lin, T. E., Hsu, C. M. & Yang, C. R., 6月 2023, 於: Biomedicine and Pharmacotherapy. 162, 114667.

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8 引文斯高帕斯（Scopus）

Tn as a potential predictor for regional lymph node metastasis in T1 colorectal cancer

Kuo, L.-J., Fang, C.-Y., Su, R.-Y., Lin, Y.-K., Wei, P.-L., Kung, C.-H. & Chen, C.-L., 10月 2023, 於: Asian Journal of Surgery. 46, 10, p. 4302-4307 6 p.

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1 引文斯高帕斯（Scopus）

Treatment Response Prediction with Circulating Tumor Cell-Derived Organoids for Soft Tissue Sarcoma

Liu, Y. W., Burnouf, T. P. R., Chang, C.-Y., Chen, S.-H., Chen, Y.-J., Chen, Y. H., Ho, W. L., Liao, Y.-M., Lin, P. C., Liu, Y. L., Miser, J. S., Wang, J. L., Wang, P. Y., Wang, S. C., Wong, T.-T., Wu, S.-P., Wu, Y. H., Chiou, J.-F. & Lu, L.-S., 6月 2023, (接受/付印).

研究成果: 會議貢獻類型 › 海报 › 同行評審

Tumor-immune microenvironment lab chip integrating liquid-dielectrophoresis operation

Chen, Y. C., Lee, K. Y., Sun, W. L., Huang, W. C., Wang, Y. S., Chang, W. C. & Liu, C. H., 4月 1 2023, 於: Japanese Journal of Applied Physics. 62, SC1049.

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Urolithin A exhibits a neuroprotective effect against Alzheimer's disease by inhibiting DYRK1A activity

Tu, H. J., Su, C. J., Peng, C. S., Lin, T. E., Fu, W. C. H., Hsu, K. C., Hwang, T. L. & Pan, S. L., 2023, 於: Journal of Food and Drug Analysis. 31, 2, p. 358-370 13 p., 12.

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8 引文斯高帕斯（Scopus）

Using alert dwell time to filter universal clinical alerts: A machine learning approach

Chien, S. C., Yang, H. C., Chen, C. Y., Chien, C. H., Hsu, C. K., Chien, P. H. & Li, Y. C., 10月 2023, 於: Computer Methods and Programs in Biomedicine. 240, 107696.

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2 引文斯高帕斯（Scopus）

What is thyroid function in your just-diagnosed cancer patient?

Hercbergs, A., Mousa, S. A., Lin, H. Y. & Davis, P. J., 2023, 於: Frontiers in Endocrinology. 14, 1109528.

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1 引文斯高帕斯（Scopus）

Whole-Exome Sequencing Identifies Genetic Variants for Severe Adolescent Idiopathic Scoliosis in a Taiwanese Population

Lin, M. R., Chou, P. H., Huang, K. J., Ting, J., Liu, C. Y., Chou, W. H., Lin, G. H., Chang, J. G., Ikegawa, S., Wang, S. T. & Chang, W. C., 1月 2023, 於: Journal of Personalized Medicine. 13, 1, 32.

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1 引文斯高帕斯（Scopus）

2022

2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside improves female ovarian aging

Lin, H. Y., Yang, Y. N., Chen, Y. F., Huang, T. Y., Crawford, D. R., Chuang, H. Y., Chin, Y. T., Chu, H. R., Li, Z. L., Shih, Y. J., Chen, Y. R., Yang, Y. C. S. H., Ho, Y., Davis, P. J., Whang-Peng, J. & Wang, K., 8月 30 2022, 於: Frontiers in Cell and Developmental Biology. 10, 862045.

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3 引文斯高帕斯（Scopus）

2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors

Wang, Y. S., Yeh, T. K., Chang, W. C., Liou, J. P., Liu, Y. M. & Huang, W. C., 12月 5 2022, 於: European Journal of Medicinal Chemistry. 243, 114773.

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2 引文斯高帕斯（Scopus）

3,6′‐ and 1,6′‐Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation

Tsai, Y. R., Kim, D. S., Hsueh, S. C., Chen, K. Y., Wu, J. C. C., Wang, J. Y., Tsou, Y. S., Hwang, I., Kim, Y., Gil, D., Jo, E. J., Han, B. S., Tweedie, D., Lecca, D., Scerba, M. T., Selman, W. R., Hoffer, B. J., Greig, N. H. & Chiang, Y. H., 5月 2022, 於: Pharmaceutics. 14, 5, 950.

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3 引文斯高帕斯（Scopus）

3-Nitrobenzanthrone promotes malignant transformation in human lung epithelial cells through the epiregulin-signaling pathway

Chen, K. Y., Tseng, C. H., Feng, P. H., Sun, W. L., Ho, S. C., Lin, C. W., Van Hiep, N., Luo, C. S., Tseng, Y. H., Chen, T. T., Liu, W. T., Lee, K. Y. & Wu, S. M., 2022, 於: Cell Biology and Toxicology. 38, 5, p. 865-887 23 p.

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4 引文斯高帕斯（Scopus）

^99mTc-TRODAT-1 SPECT Revealed That Striatal Dopamine Transport Availability Significantly Decreases in Late Mid-Aged Healthy Taiwanese and Then Remains Stable

Yeh, S. H. H., Tsai, C. J., Yu, T. H., Chiang, Y. H., Lin, S. Z., Peng, N. J. & Huang, W. S., 3月 1 2022, 於: Clinical Nuclear Medicine. 47, 3, p. 201-208 8 p.

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3 引文斯高帕斯（Scopus）

Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier

Sharma, R., Chatterjee, E., Mathew, J., Sharma, S., Rao, N. V., Pan, C. H., Lee, S. B., Dhingra, A., Grewal, A. S., Liou, J. P., Guru, S. K. & Nepali, K., 10月 5 2022, 於: European Journal of Medicinal Chemistry. 240, 114602.

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7 引文斯高帕斯（Scopus）

Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells

Jayakumar, T., Huang, C. J., Yen, T. L., Hsia, C. W., Sheu, J. R., Bhavan, P. S., Huang, W. C., Hsieh, C. Y. & Hsia, C. H., 8月 2022, 於: Molecules. 27, 16, 5143.

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18 引文斯高帕斯（Scopus）

Addressing the ACGME Competency of Communicating with the Public through the Use of TEDx Talks

Lin, A. P., Liu, S. Y., Chen, T. T., Huang, S. Y., Wu, B. W., Lin, Y. K. & Tam, K. W., 12月 2022, 於: Southern Medical Journal. 115, 12, p. 880-886 7 p.

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Adlay Seed (Coix lacryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract Fractions and Subfractions Induce Cell Cycle Arrest and Apoptosis in Human Breast and Cervical Cancer Cell Lines

Chiang, Y. F., Chung, C. P., Lin, J. H., Chiang, W., Chen, H. Y., Ali, M., Shih, Y. H., Wang, K. L., Huang, T. C., Chang, H. Y., Lin, L. C., Shieh, T. M. & Hsia, S. M., 7月 2022, 於: Molecules. 27, 13, 3984.

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8 引文斯高帕斯（Scopus）

Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma

Chien, T. C., Chien, M. M., Liu, T. L., Chang, H., Tsai, M. L., Tseng, S. H., Ho, W. L., Su, Y. Y., Lin, H. C., Lu, J. H., Chang, C. Y., Hsieh, K. L. C., Wong, T. T., Miser, J. S. & Liu, Y. L., 8月 2022, 於: Children. 9, 8, 1238.

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1 引文斯高帕斯（Scopus）

A Few-Shot Learning Approach Assists in the Prognosis Prediction of Magnetic Resonance-Guided Focused Ultrasound for the Local Control of Bone Metastatic Lesions

Hsu, F. C., Lee, H. L., Chen, Y. J., Shen, Y. A., Tsai, Y. C., Wu, M. H., Kuo, C. C., Lu, L. S., Yeh, S. D., Huang, W. S., Shen, C. N. & Chiou, J. F., 1月 1 2022, 於: Cancers. 14, 2, 445.

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6 引文斯高帕斯（Scopus）

AI4AVP: An antiviral peptides predictor in deep learning approach with generative adversarial network data augmentation

Lin, T. T., Sun, Y. Y., Wang, C. T., Cheng, W. C., Lu, I. H., Lin, C. Y. & Chen, S. H., 2022, 於: Bioinformatics Advances. 2, 1, vbac080.

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15 引文斯高帕斯（Scopus）

Air pollution enhance the progression of restrictive lung function impairment and diffusion capacity reduction: an elderly cohort study

Chen, C. H., Wu, C. D., Lee, Y. L., Lee, K. Y., Lin, W. Y., Yeh, J. I., Chen, H. C. & Guo, Y. L. L., 12月 2022, 於: Respiratory Research. 23, 1, 186.

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11 引文斯高帕斯（Scopus）

Air pollution-regulated E-cadherin mediates contact inhibition of proliferation via the hippo signaling pathways in emphysema

Chang, J. H., Lee, Y. L., Laiman, V., Han, C. L., Jheng, Y. T., Lee, K. Y., Yeh, C. T., Kuo, H. P., Chung, K. F., Heriyanto, D. S., Hsiao, T. C., Wu, S. M., Ho, S. C., Chuang, K. J. & Chuang, H. C., 1月 2022, 於: Chemico-Biological Interactions. 351, 109763.

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12 引文斯高帕斯（Scopus）

Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53

Wang, W. L., Batzorig, U., Hung, C. S., Wei, P. L., Huang, C. Y. & Chang, Y. J., 2022, 於: BioMed Research International. 2022, 1322788.

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3 引文斯高帕斯（Scopus）

Alerts in Clinical Decision Support Systems (CDSS): A Bibliometric Review and Content Analysis

Chien, S. C., Chen, Y. L., Chien, C. H., Chin, Y. P., Yoon, C. H., Chen, C. Y., Yang, H. C. & Li, Y. C., 4月 2022, 於: Healthcare (Switzerland). 10, 4, 601.

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11 引文斯高帕斯（Scopus）

Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression

Feng, Y. H., Lim, S. W., Lin, H. Y., Wang, S. A., Hsu, S. P., Kao, T. J., Ko, C. Y. & Hsu, T. I., 5月 2022, 於: Journal of Steroid Biochemistry and Molecular Biology. 219, p. 106067 106067.

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7 引文斯高帕斯（Scopus）

Altered diffusivity of the subarachnoid cisterns in the rat brain following neurological disorders

Tazoe, J., Lu, C. F., Hsieh, B. Y., Chen, C. Y. & Kao, Y. C. J., 2022, (接受/付印) 於: Biomedical Journal. 46, 1, p. 134-143 10 p.

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2 引文斯高帕斯（Scopus）

A metagenomics study of hexabromocyclododecane degradation with a soil microbial community

Li, Y. J., Chuang, C. H., Cheng, W. C., Chen, S. H., Chen, W. L., Lin, Y. J., Lin, C. Y. & Shih, Y. H., 5月 15 2022, 於: Journal of Hazardous Materials. 430, 128465.

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18 引文斯高帕斯（Scopus）

Amphiregulin induces CCN2 and fibronectin expression by TGF-β through EGFR-dependent pathway in lung epithelial cells

Cheng, W. H., Kao, S. Y., Chen, C.-L., Yuliani, F. S., Lin, L. Y., Lin, C. H. & Chen, B.-C., 12月 2022, 於: Respiratory Research. 23, 1, 381.

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14 引文斯高帕斯（Scopus）

臺北醫學大學癌症轉譯研究中心

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