癌症生物學與藥物研發研究所

2024

An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors

Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., 6月 2024, 於: Protein Science. 33, 6, e5007.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

A new potential therapeutic approach for ALS: A case report with NGS analysis

Hu, C. J., Chen, P. C., Padmanabhan, N., Zahn, A., Ho, C. M., Wang, K. & Yen, Y., 3月 1 2024, 於: Medicine (United States). 103, 9, p. E37401

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress

Wu, L. H., Cheng, Y. W., Lin, F. L., Hsu, K. C., Wang, M. H., Yen, J. L., Wang, T. J., Lin, T. E., Liu, Y. C., Huang, W. J. & Hsiao, G., 5月 2024, 於: Biomedicine and Pharmacotherapy. 174, 116538.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells

Chan, T. S., Cheng, L. H., Hsu, C. C., Yang, P. M., Liao, T. Y., Hsieh, H. Y., Lin, P. C., HuangFu, W. C., Chuu, C. P. & Tsai, K. K., 2024, (接受/付印) 於: Molecular Oncology. 18, 3, p. 562-579 18 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Discovery of Novel Spike Inhibitors against SARS-CoV-2 Infection

Tai, L. T., Yeh, C. Y., Chang, Y. J., Liu, J. F., Hsu, K. C., Cheng, J. C. & Lu, C. H., 6月 2024, 於: International journal of molecular sciences. 25, 11, 6105.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Exosomes derived from Polygonum multiflorum-treated human dental pulp stem cells (hDPSCs): New approach in regenerative medicine

Chen, T. Y., Huang, T. Y., Chung, Y. Y., Lin, W. C., Lin, H. Y., Chiu, H. C. & Lee, S. Y., 9月 2024, 於: Journal of Drug Delivery Science and Technology. 99, 105941.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Chen, Z., Guo, X., Tao, R., Huyghe, J. R., Law, P. J., Fernandez-Rozadilla, C., Ping, J., Jia, G., Long, J., Li, C., Shen, Q., Xie, Y., Timofeeva, M. N., Thomas, M., Schmit, S. L., Díez-Obrero, V., Devall, M., Moratalla-Navarro, F., Fernandez-Tajes, J. & Palles, C. 及其他185, Sherwood, K., Briggs, S. E. W., Svinti, V., Donnelly, K., Farrington, S. M., Blackmur, J., Vaughan-Shaw, P. G., Shu, X. O., Lu, Y., Broderick, P., Studd, J., Harrison, T. A., Conti, D. V., Schumacher, F. R., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. O., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J. L., Jenkins, M. A., Win, A. K., Pai, R. K., Figueiredo, J. C., Haile, R. W., Gallinger, S., Woods, M. O., Newcomb, P. A., Duggan, D., Cheadle, J. P., Kaplan, R., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, J. P., Jousilahti, P., Knekt, P., Aaltonen, L. A., Rissanen, H., Pukkala, E., Eriksson, J. G., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Männistö, S., Albanes, D., Weinstein, S. J., Ruiz-Narvaez, E., Palmer, J. R., Buchanan, D. D., Platz, E. A., Visvanathan, K., Ulrich, C. M., Siegel, E., Brezina, S., Gsur, A., Campbell, P. T., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M. L., Potter, J. D., Tsilidis, K. K., Schulze, M. B., Gunter, M. J., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Bishop, D. T., Giles, G. G., Southey, M. C., Idos, G. E., McDonnell, K. J., Abu-Ful, Z., Greenson, J. K., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T. O., van Guelpen, B., Hudson, T. J., Hampel, H., Pearlman, R., Berndt, S. I., Hayes, R. B., Martinez, M. E., Thomas, S. S., Pharoah, P. D. P., Larsson, S. C., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K. F., Pugh, E., Shelford, T., Chan, A. T., Cruz-Correa, M., Lindblom, A., Hunter, D. J., Joshi, A. D., Schafmayer, C., Scacheri, P. C., Kundaje, A., Schoen, R. E., Hampe, J., Stadler, Z. K., Vodicka, P., Vodickova, L., Vymetalkova, V., Edlund, C. K., Gauderman, W. J., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S. J., van Duijnhoven, F., Feskens, E. J. M., Sakoda, L. C., Gago-Dominguez, M., Wolk, A., Pardini, B., FitzGerald, L. M., Lee, S. C., Ogino, S., Bien, S. A., Kooperberg, C., Li, C. I., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Yamaji, T., Sawada, N., Iwasaki, M., Le Marchand, L., Wu, A. H., Qu, C., McNeil, C. E., Coetzee, G., Hayward, C., Deary, I. J., Harris, S. E., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Lau, K. S., Zhao, H., Hsu, L., Cai, Q., Dunlop, M. G., Gruber, S. B., Houlston, R. S., Moreno, V., Casey, G., Peters, U., Tomlinson, I. & Zheng, W., 12月 2024, 於: Nature Communications. 15, 1, 3557.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Hinokitiol Inhibits Breast Cancer Cells In Vitro Stemness-Progression and Self-Renewal with Apoptosis and Autophagy Modulation via the CD44/Nanog/SOX2/Oct4 Pathway

Chiang, Y. F., Huang, K. C., Chen, H. Y., Hamdy, N. M., Huang, T. C., Chang, H. Y., Shieh, T. M., Huang, Y. J. & Hsia, S. M., 4月 2024, 於: International journal of molecular sciences. 25, 7, 3904.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Hypoxia-induced long non-coding RNA HIF1A‑AS2 regulates stability of MHC class I protein in head and neck cancer

Liao, T.-T., Chen, Y.-H., Li, Z.-Y., Hsiao, A.-C., Huang, Y.-L., Hao, R.-X., Tai, S.-K., Chu, P.-Y., Shih, J.-W., Kung, H.-J. & Yang, M.-H., 6月 26 2024, (打印前電子出版) 於: Cancer immunology research.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule

Wu, Y. W., HuangFu, W. C., Lin, T. E., Peng, C. H., Tu, H. J., Sung, T. Y., Sung, T. Y., Yen, S. C., Pan, S. L. & Hsu, K. C., 2月 2024, 於: International Journal of Biological Macromolecules. 259, 129074.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Immunosuppressive role of BDNF in therapy-induced neuroendocrine prostate cancer

Liu, Y. N., Chen, W. Y., Liu, M. K., Yeh, H. L., Chen, W. H., Jiang, K. C., Li, H. R., Chen, Z. Q., Wang, W. H., Abou-Kheir, W. & Wen, Y. C., 2024, (接受/付印) 於: Molecular Oncology. 18, 6, p. 1665-1686 22 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

In silico identification of a novel Cdc2-like kinase 2 (CLK2) inhibitor in triple negative breast cancer

Huang, C. C., Hsu, C. M., Chao, M. W., Hsu, K. C., Lin, T. E., Yen, S. C., Tu, H. J. & Pan, S. L., 6月 2024, 於: Protein Science. 33, 6, e5004.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Intracellular domain of epithelial cell adhesion molecule induces Wnt receptor transcription to promote colorectal cancer progression

Panda, S. S., Lee, C. C., Geevimaan, K., Chen, K. C., Yang, S. H., Shen, C. N., HuangFu, W. C. & Wu, H. C., 12月 2024, 於: Journal of Biomedical Science. 31, 1, 72.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Layer-by-layer assembly of quercetin-loaded zein/γPGA/low-molecular-weight chitosan/fucoidan nanosystem for targeting inflamed blood vessels

Lu, H. Y., Mi, F. L., Chou, C. M., Lin, C., Chen, Y. Y., Chu, C. Y., Liu, C. Y., Lee, Y. L. A., Shih, C. C. & Cheng, C. H., 5月 2024, 於: International Journal of Biological Macromolecules. 267, 131369.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

MCTP1 increases the malignancy of androgen-deprived prostate cancer cells by inducing neuroendocrine differentiation and EMT

Liu, Y. N., Chen, W. Y., Yeh, H. L., Chen, W. H., Jiang, K. C., Li, H. R., Thuy Dung, P. V., Chen, Z. Q., Lee, W. J., Hsiao, M., Huang, J. & Wen, Y. C., 2024, 於: Science Signaling. 17, 840, adc9142.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Preclinical Repurposing of Sitagliptin as a Drug Candidate for Colorectal Cancer by Targeting CD24/CTNNB1/SOX4-Centered Signaling Hub

Shih, J. W., Wu, A. T. H., Mokgautsi, N., Wei, P. L. & Huang, Y. J., 1月 2024, 於: International journal of molecular sciences. 25, 1, 609.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

Receptor Ligand-Free Mesoporous Silica Nanoparticles: A Streamlined Strategy for Targeted Drug Delivery across the Blood-Brain Barrier

Chen, Z. A., Wu, C. H., Wu, S. H., Huang, C. Y., Mou, C. Y., Wei, K. C., Yen, Y., Chien, I. T., Runa, S., Chen, Y. P. & Chen, P., 5月 21 2024, 於: ACS Nano. 18, 20, p. 12716-12736 21 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

6 引文斯高帕斯（Scopus）

Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer and overcoming drug resistance

Hsieh, Y. Y., Du, J. L. & Yang, P. M., 2月 2024, 於: Molecular Oncology. 18, 2, p. 386-414 29 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

Scutellaria baicalensis Induces Cell Apoptosis and Elicits Mesenchymal–Epithelial Transition to Alleviate Metastatic Hepatocellular Carcinoma via Modulating HSP90β

Wu, T. H., Lin, T. Y., Yang, P. M., Li, W. T., Yeh, C. T. & Pan, T. L., 3月 2024, 於: International journal of molecular sciences. 25, 5, 3073.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

Structure-based design, synthesis and biological evaluation of N-substituted 6H-thiochromeno[2,3–c]quinolin-12(12H)-one as potential breast cancer drugs

Sumitra, M. R., Chen, L. C., Tsai, W. C., Ansar, M., Lawal, B., Mokgautsi, N., Guh, J. H., Wu, A. T. H. & Huang, H. S., 1月 2024, 於: Arabian Journal of Chemistry. 17, 1, 105423.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function

Chen, C. H., Lin, H. W., Huang, M. F., Chiang, C. W., Lee, K. H., Phuong, N. T., Cai, Z. Y., Chang, W. C. & Lin, D. Y., 12月 2024, 於: BMC Molecular and Cell Biology. 25, 1, 2.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

The Effect of Oncology Nurse Navigation on Mental Health in Patients with Cancer in Taiwan: A Randomized Controlled Clinical Trial

Yu, W. Z., Wang, H. F., Lin, Y. K., Liu, Y. L., Yen, Y., Whang-Peng, J., Huang, T. W. & Chang, H. J., 7月 2024, 於: Current Oncology. 31, 7, p. 4105-4122 18 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2023

A low-molecular-weight chitosan fluorometric-based assay for evaluating antiangiogenic drugs

Wang, C. Y., Chou, C. M., Chu, C. Y., Chen, A., Liu, E. H., Liu, C. Y., Lee, Y. L. A., Mi, F. L. & Cheng, C. H., 1月 2023, 於: International Journal of Biological Macromolecules. 224, p. 927-937 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

2 引文斯高帕斯（Scopus）

An ATP-sensitive phosphoketolase regulates carbon fixation in cyanobacteria

Lu, K. J., Chang, C. W., Wang, C. H., Chen, F. Y. H., Huang, I. Y., Huang, P. H., Yang, C. H., Wu, H. Y., Wu, W. J., Hsu, K. C., Ho, M. C. & Tsai, M. D., 7月 2023, 於: Nature Metabolism. 5, 7, p. 1111-1126 16 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

10 引文斯高帕斯（Scopus）

An auristatin-based antibody-drug conjugate targeting EphA2 in pancreatic cancer treatment

Chang, F. L., Lee, C. C., Tsai, K. C., Lin, T. Y., Chiang, C. W., Pan, S. L. & Lee, Y. C., 12月 25 2023, 於: Biochemical and Biophysical Research Communications. 688, 149214.

研究成果: 雜誌貢獻 › 文章 › 同行評審

2 引文斯高帕斯（Scopus）

A Novel Isotope-labeled Small Molecule Probe CC12 for Anti-glioma via Suppressing LYN-mediated Progression and Activating Apoptosis Pathways

Huang, H. S., Chiang, I. T., Lawal, B., Weng, Y. S., Jeng, L. B., Kuo, Y. C., Liu, Y. C. & Hsu, F. T., 2023, 於: International Journal of Biological Sciences. 19, 10, p. 3209-3225 17 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells

Tsai, F. L., Huang, H. L., Lai, M. J., Liou, J. P., Pan, S. L. & Yang, C. R., 8月 2023, 於: International journal of molecular sciences. 24, 16, 12588.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Apigetrin-enriched Pulmeria alba extract prevents assault of STZ on pancreatic β-cells and neuronal oxidative stress with concomitant attenuation of tissue damage and suppression of inflammation in the brain of diabetic rats

Abdulrasheed-Adeleke, T., Lawal, B., Agwupuye, E. I., Kuo, Y., Eni, A. M., Ekoh, O. F., Lukman, H. Y., Onikanni, A. S., Olawale, F., Saidu, S., Ibrahim, Y. O., Al Ghamdi, M. A. S., Aggad, S. S., Alsayegh, A. A., Aljarba, N. H., Batiha, G. E. S., Wu, A. T. H. & Huang, H. S., 6月 2023, 於: Biomedicine and Pharmacotherapy. 162, 114582.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

7 引文斯高帕斯（Scopus）

ASPM activates Hedgehog and Wnt signaling to promote small cell lung cancer stemness and progression

Cheng, L.-H., Hsu, C.-C., Tsai, H.-W., Liao, W.-Y., Yang, P.-M., Liao, T.-Y., Hsieh, H.-Y., Chan, T.-S. & Tsai, K. K., 1月 1 2023, 於: Cancer Research.

研究成果: 雜誌貢獻 › 文章 › 同行評審

12 引文斯高帕斯（Scopus）

Assessing the skin-whitening property of plant extracts from taiwanese species using zebrafish as a rapid screening platform

Hsiao, S. W., Kuo, I. C., Syu, L. L., Lee, T. H., Cheng, C. H., Mei, H. C. & Lee, C. K., 9月 2023, 於: Arabian Journal of Chemistry. 16, 9, 105035.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

3 引文斯高帕斯（Scopus）

Association of diabetes mellitus with early-onset colorectal cancer: A systematic review and meta-analysis of 19 studies including 10 million individuals and 30,000 events

Khoa Ta, H. D., Nguyen, N. N., Ho, D. K. N., Nguyen, H. D., Ni, Y.-C., Yee, K. X., Pan, S.-R., Nguyen, H. S., Thai Hoang Phuoc, T., Chen, M.-J. & Lee, K.-H., 8月 17 2023, 於: Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 17, 8, p. 102828

研究成果: 雜誌貢獻 › 文章 › 同行評審

6 引文斯高帕斯（Scopus）

Attenuation of hyperglycemia-associated dyslipidemic, oxidative, cognitive, and inflammatory crises via modulation of neuronal ChEs/NF-κB/COX-2/NOx, and hepatorenal functional deficits by the Tridax procumbens extract

Hogan, I. A., Kuo, Y. C., Abubakar, A. N., Lawal, B., Agboola, A. R., Lukman, H. Y., Onikanni, S. A., Olawale, F., Fadaka, A. O., Ibrahim, Y. O., Babalola, S. B., Batiha, G. E. S., Albogami, S. M., Alorabi, M., De Waard, M. & Huang, H. S., 2月 2023, 於: Biomedicine and Pharmacotherapy. 158, 114114.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

5 引文斯高帕斯（Scopus）

Biological cell trapping and manipulation of a photonic nanojet by a specific microcone-shaped optical fiber tip

Chen, W. Y., Liu, Y. Y., Kong, J. A. N., Li, L. P. H., Chen, Y. B., Cheng, C. H. & Liu, C. Y., 3月 1 2023, 於: Optics Letters. 48, 5, p. 1216-1219 4 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

7 引文斯高帕斯（Scopus）

Capsaicin alleviates cisplatin-induced muscle loss and atrophy in vitro and in vivo

Huang, K. C., Chiang, Y. F., Huang, T. C., Chen, H. Y., Lin, P. H., Ali, M. & Hsia, S. M., 2月 2023, 於: Journal of Cachexia, Sarcopenia and Muscle. 14, 1, p. 182-197 16 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

17 引文斯高帕斯（Scopus）

Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer

Lin, C. H., Lin, W. D., Huang, Y. C., Chen, Y. C., Loh, Z. J., Ger, L. P., Lin, F. C., Li, H. Y., Cheng, H. C., Lee, K. H., Hsiao, M. & Lu, P. J., 3月 2023, (接受/付印) 於: Cancer Gene Therapy. 30, 3, p. 404-413 10 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

4 引文斯高帕斯（Scopus）

CHRM4/AKT/MYCN upregulates interferon alpha-17 in the tumor microenvironment to promote neuroendocrine differentiation of prostate cancer

Wen, Y.-C., Tram, V. T. N., Chen, W.-H., Li, C.-H., Yeh, H. L., Thuy Dung, P. V., Jiang, K.-C., Li, H.-R., Huang, J., Hsiao, M., Chen, W.-Y. & Liu, Y.-N., 5月 4 2023, 於: Cell death & disease. 14, 5, p. 304 304.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

4 引文斯高帕斯（Scopus）

Combining virtual screening with cis-/trans-cleavage enzymatic assays effectively reveals broad-spectrum inhibitors that target the main proteases of SARS-CoV-2 and MERS-CoV

Chang, Y. J., Le, U. N. P., Liu, J. J., Li, S. R., Chao, S. T., Lai, H. C., Lin, Y. F., Hsu, K. C., Lu, C. H. & Lin, C. W., 8月 2023, 於: Antiviral Research. 216, 105653.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Computational identification of novel signature of T2DM-induced nephropathy and therapeutic bioactive compounds from Azanza garckeana

Lawal, B., Kuo, Y. C., Onikanni, S. A., Chen, Y.-F., Abdulrasheed-Adeleke, T., Fadaka, A. O., Olugbodi, J. O., Lukman, H. Y., Olawale, F., Mahmoud, M. H., Batiha, G.E.-S., Wu, A. T. & Huang, H.-S., 7月 15 2023, 於: American Journal of Translational Research. 15, 7, p. 4504-4520 17 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Fernandez-Rozadilla, C., Timofeeva, M., Chen, Z., Law, P., Thomas, M., Schmit, S., Díez-Obrero, V., Hsu, L., Fernandez-Tajes, J., Palles, C., Sherwood, K., Briggs, S., Svinti, V., Donnelly, K., Farrington, S., Blackmur, J., Vaughan-Shaw, P., Shu, X. O., Long, J. & Cai, Q. 及其他190, Guo, X., Lu, Y., Broderick, P., Studd, J., Huyghe, J., Harrison, T., Conti, D., Dampier, C., Devall, M., Schumacher, F., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Moratalla-Navarro, F., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. O., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J., Jenkins, M., Win, A. K., Pai, R., Figueiredo, J., Haile, R., Gallinger, S., Woods, M., Newcomb, P., Duggan, D., Cheadle, J., Kaplan, R., Maughan, T., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, L. P., Jousilahti, P., Knekt, P., Aaltonen, L., Rissanen, H., Pukkala, E., Eriksson, J., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Zanke, B., Männistö, S., Albanes, D., Weinstein, S., Ruiz-Narvaez, E., Palmer, J., Buchanan, D., Platz, E., Visvanathan, K., Ulrich, C., Siegel, E., Brezina, S., Gsur, A., Campbell, P., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M., Potter, J., Tsilidis, K., Schulze, M., Gunter, M., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Stern, M., Pardamean, B., Bishop, T., Giles, G., Southey, M., Idos, G., McDonnell, K., Abu-Ful, Z., Greenson, J., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T., van Guelpen, B., Hudson, T., Hampel, H., Pearlman, R., Berndt, S., Hayes, R., Martinez, M. E., Thomas, S., Corley, D., Pharoah, P., Larsson, S., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K., Pugh, E., Shelford, T., Chan, A., Cruz-Correa, M., Lindblom, A., Hunter, D., Joshi, A., Schafmayer, C., Scacheri, P., Kundaje, A., Nickerson, D., Schoen, R., Hampe, J., Stadler, Z., Vodicka, P., Vodickova, L., Vymetalkova, V., Papadopoulos, N., Edlund, C., Gauderman, W., Thomas, D., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S., van Duijnhoven, F., Feskens, E., Sakoda, L., Gago-Dominguez, M., Wolk, A., Naccarati, A., Pardini, B., FitzGerald, L., Lee, S. C., Ogino, S., Bien, S., Kooperberg, C., Li, C., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Tangen, C., Mardis, E., Yamaji, T., Sawada, N., Iwasaki, M., Haiman, C., Le Marchand, L., Wu, A., Qu, C., McNeil, C., Coetzee, G., Hayward, C., Deary, I., Harris, S., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Moreno, V., Casey, G., Gruber, S., Tomlinson, I., Zheng, W., Dunlop, M., Houlston, R. & Peters, U., 1月 2023, 於: Nature Genetics. 55, 1, p. 89-99 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

53 引文斯高帕斯（Scopus）

Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma

Tseng, H. J., Banerjee, S., Qian, B., Lai, M. J., Wu, T. Y., Hsu, T. I., Lin, T. E., Hsu, K. C., Chuang, K. H., Liou, J. P. & Shih, J. C., 8月 2023, 於: European Journal of Medicinal Chemistry. 256, 115459.

研究成果: 雜誌貢獻 › 文章 › 同行評審

5 引文斯高帕斯（Scopus）

Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors

Hsu, J. Y., Hsu, K. C., Sun, C., Chou, C. H., Lin, T. E., Sung, T. Y., Tseng, H. J., Yen, S. C., Yang, C. R. & Huang, W. J., 3月 2023, 於: Biomedicine and Pharmacotherapy. 159, 114258.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

4 引文斯高帕斯（Scopus）

Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer

Li, M. C., Coumar, M. S., Lin, S. Y., Lin, Y. S., Huang, G. L., Chen, C. H., Lien, T. W., Wu, Y. W., Chen, Y. T., Chen, C. P., Huang, Y. C., Yeh, K. C., Yang, C. M., Kalita, B., Pan, S. L., Hsu, T. A., Yeh, T. K., Chen, C. T. & Hsieh, H. P., 2月 2023, 於: Journal of Medicinal Chemistry. 66, 4, p. 2566-2588 23 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

7 引文斯高帕斯（Scopus）

Disruption of CCL2 in Mesenchymal Stem Cells as an Anti-Tumor Approach against Prostate Cancer

Bui, Q. T., Lee, K. D., Fan, Y. C., Lewis, B. S., Deng, L. W. & Tsai, Y. C., 1月 2023, 於: Cancers. 15, 2, 441.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

4 引文斯高帕斯（Scopus）

Dysbindin Domain-Containing 1 in Prostate Cancer: New Insights into Bioinformatic Validation of Molecular and Immunological Features

Tram, V. T. N., Khoa Ta, H. D., Anuraga, G., Dung, P. V. T., Xuan, D. T. M., Dey, S., Wang, C. Y. & Liu, Y. N., 8月 2023, 於: International journal of molecular sciences. 24, 15, 11930.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Effectiveness of anti-erythropoietin producing Hepatocellular receptor Type-A2 antibody in pancreatic cancer treatment

Chang, F. L., Tsai, K. C., Lin, T. Y., Chiang, C. W., Pan, S. L. & Lee, Y. C., 11月 2023, 於: Heliyon. 9, 11, e21774.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Effectiveness of Stereotactic Ablative Radiotherapy for Systemic Therapy Respondents with Inoperable Pulmonary Oligometastases and Oligoprogression

Ho, C. B., Tsai, J. T., Chen, C. Y., Shiah, H. S., Chen, H. Y., Ting, L. L., Kuo, C. C., Lai, I. C., Lai, H. Y., Chung, C. L., Lee, K. L., Tzeng, H. E., Lee, K. H., Lee, H. L., Chen, S. W. & Chiou, J. F., 5月 2023, 於: Diagnostics. 13, 9, 1597.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Effect of Vitamin D Supplementation on Primary Dysmenorrhea: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Chen, Y. C., Chiang, Y. F., Lin, Y. J., Huang, K. C., Chen, H. Y., Hamdy, N. M., Huang, T. C., Chang, H. Y., Shieh, T. M., Huang, Y. J. & Hsia, S. M., 6月 21 2023, 於: Nutrients. 15, 13, 2830.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

Establishment of extensive artificial intelligence models for kinase inhibitor prediction: Identification of novel PDGFRB inhibitors

Lien, S. T., Lin, T. E., Hsieh, J. H., Sung, T. Y., Chen, J. H. & Hsu, K. C., 4月 2023, 於: Computers in Biology and Medicine. 156, 106722.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

4 引文斯高帕斯（Scopus）

Exploration of anti-leukemic effect of soft coral-derived 13-acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock protein 90 and topoisomerase II

Chin, H. K., Lu, M. C., Hsu, K. C., El-Shazly, M., Tsai, T. N., Lin, T. Y., Shih, S. P., Lin, T. E., Wen, Z. H., Yang, Y. C. S. H. & Liu, Y. C., 7月 2023, 於: Kaohsiung Journal of Medical Sciences. 39, 7, p. 718-731 14 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

Frizzled 7 modulates goblet and Paneth cell fate, and maintains homeostasis in mouse intestine

Gu, N. X., Guo, Y. R., Lin, S. E., Wang, Y. H., Lin, I. H., Chen, Y. F. & Yen, Y., 2月 2023, 於: Development (Cambridge). 150, 4, dev200932.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

5 引文斯高帕斯（Scopus）

癌症生物學與藥物研發研究所

研究成果

搜尋結果