實驗動物中心

2024

Chronopharmacology of diuresis via metabolic profiling and key biomarker discovery of the traditional Chinese prescription Ji-Ming-San using tandem mass spectrometry in rat models

Hsieh, C. Y., Tsai, P. W., Tomioka, Y., Matsumoto, Y., Akiyama, Y., Wang, C. C., Tayo, L. L. & Lee, C. J., 2月 2024, 於: Phytomedicine. 124, 155260.

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Inflammatory and immunopathological differences in brains of permissive and non-permissive hosts with Angiostrongylus cantonensis infection can be identified using¹⁸F/FDG/PET-imaging

Chang, K. W., Wang, L. C., Wang, H. Y., Lin, T. Y., Hwu, E. E. T. & Cheng, P. C., 5月 2024, 於: PLoS Neglected Tropical Diseases. 18, 5, e0012188.

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2023

Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer

Lin, C. H., Lin, W. D., Huang, Y. C., Chen, Y. C., Loh, Z. J., Ger, L. P., Lin, F. C., Li, H. Y., Cheng, H. C., Lee, K. H., Hsiao, M. & Lu, P. J., 3月 2023, (接受/付印) 於: Cancer Gene Therapy. 30, 3, p. 404-413 10 p.

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4 引文斯高帕斯（Scopus）

Propolis Has an Anticancer Effect on Early Stage Colorectal Cancer by Affecting Epithelial Differentiation and Gut Immunity in the Tumor Microenvironment

Shen, M. H., Liu, C. Y., Chang, K. W., Lai, C. L., Chang, S. C. & Huang, C. J., 11月 2023, 於: Nutrients. 15, 21, 4494.

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2 引文斯高帕斯（Scopus）

The Titrated Mannitol Improved Central [^99mTc] Tc TRODAT-1 Uptake in an Animal Model—A Clinically Feasible Application

Chang, K. W., Chang, P. L., Tsai, C. J., Tsai, Y. J., Wu, P. H., Lee, H. L., Lai, Y. H., Wong, C. Y. O. & Huang, W. S., 2月 2023, 於: International journal of molecular sciences. 24, 4, 3773.

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2022

Butyrate supplementation regulates expression of chromosome segregation 1‑like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer

Chang, C. C., Kao, W. Y., Liu, C. Y., Su, H. H., Kan, Y. A., Lin, P. Y., Ku, W. C., Chang, K. W., Yang, R. N. & Huang, C. J., 6月 1 2022, 於: International Journal of Oncology. 60, 6, 64.

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9 引文斯高帕斯（Scopus）

Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple-negative breast cancers

Hsiao, Y. W., Chi, J. Y., Li, C. F., Chen, L. Y., Chen, Y. T., Liang, H. Y., Lo, Y. C., Hong, J. Y., Chuu, C. P., Hung, L. Y., Du, J. Y., Chang, W. C. & Wang, J. M., 1月 2022, 於: Clinical and Translational Medicine. 12, 1, e724.

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17 引文斯高帕斯（Scopus）

Microstructural Evidence of Neuroinflammation for Psychological Symptoms and Pain in Patients With Fibromyalgia

Lo, Y. C., Li, T. J. T., Lin, T. C., Chen, Y. Y. & Kang, J. H., 8月 2022, 於: Journal of Rheumatology. 49, 8, p. 942-947 6 p.

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6 引文斯高帕斯（Scopus）

Restoring Prohealing/Remodeling-Associated M2a/c Macrophages Using ON101 Accelerates Diabetic Wound Healing

Lin, C. W., Chen, C. C., Huang, W. Y., Chen, Y. Y., Chen, S. T., Chou, H. W., Hung, C. M., Chen, W. J., Lu, C. S., Nian, S. X., Chen, S. G., Chang, H. W., Chang, V. H. S., Liu, L. Y., Kuo, M. L. & Chang, S. C., 9月 2022, 於: JID Innovations. 2, 5, 100138.

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22 引文斯高帕斯（Scopus）

2021

HDACi protects against vascular cognitive impairment from CCH injury via induction of BDNF-related AMPA receptor activation

Fang, Y. C., Hsieh, J. Y., Vidyanti, A. N., Yang, C. H., Jan, J. S., Chang, K. W., Hu, C. J. & Tu, Y. K., 8月 2021, 於: Journal of Cellular and Molecular Medicine. 25, 15, p. 7418-7425 8 p.

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7 引文斯高帕斯（Scopus）

Intercomparison of conventional and QuickScan dicentric scoring for the validation of individual biodosimetry analysis in Taiwan

Lin, W. C., Chang, K. W., Liao, T. Z., Ou Yang, F. Y., Chang, T. J., Yuan, M. C., Wilkins, R. C. & Chang, C. H., 2021, 於: International Journal of Radiation Biology. 97, 7, p. 916-925 10 p.

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2 引文斯高帕斯（Scopus）

Platelet-derived growth factor receptor-α subunit targeting suppresses metastasis in advanced thyroid cancer in vitro and in vivo

Lin, C. L., Tsai, M. L., Chen, Y. H., Liu, W. N., Lin, C. Y., Hsu, K. W., Huang, C. Y., Chang, Y. J., Wei, P. L., Chen, S. H., Huang, L. C. & Lee, C. H., 9月 2021, 於: Biomolecules and Therapeutics. 29, 5, p. 551-561 11 p.

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11 引文斯高帕斯（Scopus）

Supplementation of probiotic Butyricicoccus pullicaecorum mediates anticancer effect on bladder urothelial cells by regulating butyrate-responsive molecular signatures

Wang, Y. C., Ku, W. C., Liu, C. Y., Cheng, Y. C., Chien, C. C., Chang, K. W. & Huang, C. J., 12月 2021, 於: Diagnostics. 11, 12, 2270.

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13 引文斯高帕斯（Scopus）

Synthesis, radiolabeling, and preliminary in vivo evaluation of [⁶⁸ga] ipcat-nota as an imaging agent for dopamine transporter

Farn, S. S., Chang, K. W., Lin, W. C., Yu, H. M., Lin, K. L., Tseng, Y. C., Chang, Y., Yu, C. S. & Lin, W. J., 2021, 於: Drug Design, Development and Therapy. 15, p. 2577-2591 15 p.

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1 引文斯高帕斯（Scopus）

2020

ABL genomic editing sufficiently abolishes oncogenesis of human chronic myeloid leukemia cells in vitro and in vivo

Chen, S. H., Hsieh, Y. Y., Tzeng, H. E., Lin, C. Y., Hsu, K. W., Chiang, Y. S., Lin, S. M., Su, M. J., Hsieh, W. S. & Lee, C. H., 5月 29 2020, 於: Cancers. 12, 6, 1399.

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16 引文斯高帕斯（Scopus）

Downregulation of STK4 promotes colon cancer invasion/migration through blocking β-catenin degradation

Lin, C. H., Hsu, T. I., Chiou, P. Y., Hsiao, M., Wang, W. C., Chen, Y. C., Lin, J. T., Wang, J. Y., Lin, P. C., Lin, F. C., Tseng, Y. K., Cheng, H. C., Chen, C. L. & Lu, P. J., 10月 1 2020, 於: Molecular Oncology. 14, 10, p. 2574-2588 15 p.

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8 引文斯高帕斯（Scopus）

Gut butyrate-producing organisms correlate to Placenta Specific 8 protein: importance to colorectal cancer progression

Huang, C.-C., Shen, M.-H., Chen, S.-K., Yang, S.-H., Liu, C.-Y., Guo, J.-W., Chang, K.-W. & Huang, C.-J., 3月 2020, 於: Journal of Advanced Research.

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24 引文斯高帕斯（Scopus）

Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats

Yang, Y. C. S. H., Chang, H. W., Lin, I. H., Chien, L. N., Wu, M. J., Liu, Y. R., Chu, P. G., Xie, G., Dong, F., Jia, W., Chang, V. H. S. & Yen, Y., 12月 1 2020, 於: Scientific Reports. 10, 1, 866.

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32 引文斯高帕斯（Scopus）

Ovatodiolide, isolated from Anisomeles indica, suppresses bladder carcinogenesis through suppression of mTOR/β-catenin/CDK6 and exosomal miR-21 derived from M2 tumor-associated macrophages

Wu, A. T. H., Srivastava, P., Yadav, V. K., Tzeng, D. T. W., Iamsaard, S., Su, E. C. Y., Hsiao, M. & Liu, M. C., 8月 15 2020, 於: Toxicology and Applied Pharmacology. 401, p. 115109 115109.

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24 引文斯高帕斯（Scopus）

2018

Therapeutic effect of repurposed temsirolimus in lung adenocarcinoma model

Chang, H. W., Wu, M. J., Lin, Z. M., Wang, C. Y., Cheng, S. Y., Lin, Y. K., Chow, Y. H., Ch'ang, H. J. & Chang, V. H. S., 7月 24 2018, 於: Frontiers in Pharmacology. 9, JUL, p. 778 778.

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5 引文斯高帕斯（Scopus）

2017

Characterization of a transgenic mouse model exhibiting spontaneous lung adenocarcinomas with a metastatic phenotype

Chang, H. W., Lin, Z. M., Wu, M. J., Wang, L. Y., Chow, Y. H., Jiang, S. S., Ch'ang, H. J. & Chang, V. H. S., 4月 2017, 於: PLoS ONE. 12, 4, e0175586.

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7 引文斯高帕斯（Scopus）

2016

Klf10 deficiency in mice exacerbates pulmonary inflammation by increasing expression of the proinflammatory molecule NPRA

Huang, L. T., Chang, H. W., Wu, M. J., Lai, Y. T., Wu, W. C., Yu, W. C. Y. & Chang, V. H. S., 10月 1 2016, 於: International Journal of Biochemistry and Cell Biology. 79, p. 231-238 8 p.

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13 引文斯高帕斯（Scopus）

2015

CDK2 phosphorylation regulates the protein stability of KLF10 by interfering with binding of the E3 ligase SIAH1

Lin, C.-H., Lin, S.-Y., Chang, H.-W., Ko, L.-J., Tseng, Y.-S., Chang, V. H. S. & Yu, W. C. Y., 5月 1 2015, 於: Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 5, p. 1174-1181 8 p.

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8 引文斯高帕斯（Scopus）

KLF10 affects pancreatic function via the SEI-1/p21^Cip1 pathway

Wu, M.-J., Wu, W.-C., Chang, H.-W., Lai, Y.-T., Lin, C.-H., Yu, W. C. Y. & Chang, V. H. S., 3月 2015, 於: International Journal of Biochemistry and Cell Biology. 60, p. 53-59 7 p.

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14 引文斯高帕斯（Scopus）

2009

The synthesis and characterization of [¹²⁴I]IMPY, a thioflavin-S derivative, in transgenic mouse models of Alzheimer's disease

Chang, K.-W., Chen, C. C., Lee, S. Y., Shen, L. H. & Wang, H. E., 7月 1 2009, 於: Applied Radiation and Isotopes. 67, 7-8, p. 1397-1400 4 p.

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3 引文斯高帕斯（Scopus）

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