生藥學研究所

2022

New ent-kaurene and germacrene derivatives from Mesona procumbens Hemseley and their biological activity

Ganzon, J. G., Liaw, C. C., Lin, Y. C., Lin, Z. H., Wang, C. H., Chen, C. Y., Chuang, K. H. & Kuo, Y. H., 2022, (接受/付印) 於: Natural Product Research.

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1 引文斯高帕斯（Scopus）

Novel Two-Step Process in Cellulose Depolymerization: Hematite-Mediated Photocatalysis by Lytic Polysaccharide Monooxygenase and Fenton Reaction

Wang, D., Kao, M-R., Li, J., Sun, P., Meng, Q., Vyas, A., Liang, P-H., Wang, Y-S. & Hsieh, Y. S. Y., 8月 17 2022, 於: Journal of Agricultural and Food Chemistry. 70, 32, p. 9941-9947 7 p.

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1 引文斯高帕斯（Scopus）

Oct-4 induces cisplatin resistance and tumor stem cell-like properties in endometrial carcinoma cells

Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 2022, (接受/付印) 於: Taiwanese Journal of Obstetrics and Gynecology.

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O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia

Yen, S. C., Wu, Y. W., Huang, C. C., Chao, M. W., Tu, H. J., Chen, L. C., Lin, T. E., Sung, T. Y., Tseng, H. J., Chu, J. C., Huang, W. J., Yang, C. R., HuangFu, W. C., Pan, S. L. & Hsu, K. C., 6月 2022, 於: Phytomedicine. 100, 154061.

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4 引文斯高帕斯（Scopus）

Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes

Kapelemera, A. M., Uang, Y-S., Wang, L-H., Wu, T-Y., Lee, F-Y., Tai, L., Wang, C-C. & Lee, C-J., 2022, 於: Frontiers in Pharmacology. 13

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1 引文斯高帕斯（Scopus）

Photo-Programmed Deformations in Rigid Liquid Crystalline Polymers Triggered by Body Temperature

Kim, H., Li, J., Hsieh, Y. S. Y., Cho, M., Ahn, S-H. & Li, C., 2022, 於: Small.

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Predictive Model for Oral Status in Elderly People in a Taiwanese Nursing Home Using a High-Protein Black Soybean Koji Food

Liao, K-W., Lo, W-L., Hsu, C-Y., Chiu, W-C., Wu, C-H., Chen, Y-W., Hsu, P-C. & Huang, H-Y., 4月 2022, 於: Frontiers in Nutrition. 9, p. 814315

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Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte

Wang, S. H., Chen, Y. S., Lai, K. H., Lu, C. K., Chang, H. S., Wu, H. C., Yen, F. L., Chen, L. Y., Lee, J. C. & Yen, C. H., 9月 2022, 於: Antioxidants. 11, 9, 1755.

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2 引文斯高帕斯（Scopus）

Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209

Chen, Y-Y., Chen, L-Y., Chen, P-J., El-Shazly, M., Peng, B-R., Chen, Y-C., Su, C-H., Su, J-H., Sung, P-J., Yen, P-T., Wang, L-S. & Lai, K-H., 4月 2 2022, 於: Metabolites. 12, 4, 320.

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1 引文斯高帕斯（Scopus）

Probiotic supplementation attenuates age-related sarcopenia via the gut–muscle axis in SAMP8 mice

Chen, L. H., Chang, S. S., Chang, H. Y., Wu, C. H., Pan, C. H., Chang, C. C., Chan, C. H. & Huang, H. Y., 2月 2022, 於: Journal of Cachexia, Sarcopenia and Muscle. 13, 1, p. 515-531 17 p.

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7 引文斯高帕斯（Scopus）

Promoter hypomethylation and overexpression of TSTD1 mediate poor treatment response in breast cancer

Ansar, M., Thu, L. T. A., Hung, C. S., Su, C. M., Huang, M. H., Liao, L. M., Chung, Y. M. & Lin, R. K., 11月 7 2022, 於: Frontiers in Oncology. 12, 1004261.

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Rational design of synthetically tractable HDAC6/HSP90 dual inhibitors to destroy immune-suppressive tumor microenvironment

Wu, T. Y., Chen, M., Chen, I. C., Chen, Y. J., Chen, C. Y., Wang, C. H., Cheng, J. J., Nepali, K., Chuang, K. H. & Liou, J. P., 2022, (接受/付印) 於: Journal of Advanced Research.

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2 引文斯高帕斯（Scopus）

Structural compositions and biological activities of cell wall polysaccharides in the rhizome, stem, and leaf of Polygonatum odoratum (Mill.) Druce

Li, J., Hsiung, S. Y., Kao, M. R., Xing, X., Chang, S. C., Wang, D., Hsieh, P. Y., Liang, P. H., Zhu, Z., Cheng, T. J. R., Shie, J. J., Liou, J. P., Abbott, D. W., Kwon, S. W. & Hsieh, Y. S. Y., 11月 2022, 於: Carbohydrate Research. 521, 108662.

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Structures and absolute configurations of excoecoumarins A and B studied by experimental and theoretical NMR and circular dichroism spectra

Chang, M. F., Chang, J. L., Cheng, C. Y., Wu, H. C., Chang, H. S. & Cheng, M. J., 2022, (接受/付印) 於: Journal of Physical Organic Chemistry.

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Synergistic deciphering of bioenergy production and electron transport characteristics to screen traditional Chinese medicine (TCM) for COVID-19 drug development

Tsai, P. W., Hsieh, C. Y., Ting, J. U., Ciou, Y. R., Lee, C. J., Hsieh, C. L., Lien, T. K., Hsueh, C. C. & Chen, B. Y., 6月 2022, 於: Journal of the Taiwan Institute of Chemical Engineers. 135, 104365.

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4 引文斯高帕斯（Scopus）

The Design, Structure–Activity, and kinetic studies of 3-Benzyl-5-oxa-1,2,3,4-Tetrahydro-2H-chromeno-(3,4-c)pyridin-8-yl sulfamates as Steroid sulfatase inhibitors

Chang, C-N., Lin, I-C., Lin, T-S., Chiu, P-F., Lu, Y-L., Narwane, M., Liu, I-C., Hng, Y., Tsai, K-C., Lin, M-H., S. Y. Hsieh, Y., Chen, M-J. & Liang, P-H., 2022, 於: Bioorganic Chemistry. 129

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Undescribed alkyne-geranylcyclohexenetriols from the endophyte Diaporthe caulivora 09F0132 and their anti-melanogenic activity

Yang, S. S., Chen, Y. F., Ko, H. H., Wu, H. C., Hsieh, S. Y., Wu, M. D., Cheng, M. J. & Chang, H. S., 10月 2022, 於: Phytochemistry. 202, 113312.

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Untargeted LC-MS/MS-Based Multi-Informative Molecular Networking for Targeting the Antiproliferative Ingredients in Tetradium ruticarpum Fruit

Su, C. H., Cheng, Y. C., Chang, Y. C., Kung, T. H., Chen, Y. L., Lai, K. H., Hsieh, H. L., Chen, C. Y., Hwang, T. L. & Yang, Y. L., 7月 2022, 於: Molecules. 27, 14, 4462.

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Vitisin A, a Resveratrol Tetramer, Improves Scopolamine-Induced Impaired Learning and Memory Functions in Amnesiac ICR Mice

Chen, L. G., Wang, C. C., Lee, Y. S., Sie, Y. Y., Chang, C. I. & Hou, W. C., 2月 2022, 於: Biomedicines. 10, 2, 273.

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1 引文斯高帕斯（Scopus）

2021

Achieving High Power Density and Long-Term Stable Flexible Triboelectric Nanogenerators through Surface Functionalization of High Work-Function Electrode with Cationic Thiol-Based Self-Assembled Monolayer

Cheng, Y. H., Lee, C. J. & Chang, C. Y., 3月 2021, 於: Advanced Materials Technologies. 6, 3, 2000985.

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5 引文斯高帕斯（Scopus）

Active Tumoral/Tumor Environmental Dual-Targeting by Non-Covalently Arming with Trispecific Antibodies or Dual-Bispecific Antibodies on Docetaxel-Loaded mPEGylated Nanocarriers to Enhance Chemotherapeutic Efficacy and Minimize Systemic Toxicity

Cheng, W. J., Lin, S. Y., Chen, M., Chen, L. C., Ho, H. O., Chuang, K. H. & Sheu, M. T., 2021, 於: International Journal of Nanomedicine. 16, p. 4017-4030 14 p.

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4 引文斯高帕斯（Scopus）

An electrostatically self-assembled fluorinated molecule as a surface modification layer for a high-performance and stable triboelectric nanogenerator

Yang, J. R., Lee, C. J. & Chang, C. Y., 2月 2021, 於: Journal of Materials Chemistry A. 9, 7, p. 4230-4239 10 p.

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8 引文斯高帕斯（Scopus）

Anti-proliferative potential of secondary metabolites from the marine sponge theonella sp. Moving from correlation toward causation

Lai, K. H., Peng, B. R., Su, C. H., El-Shazly, M., Sun, Y. L., Shih, M. C., Huang, Y. T., Yen, P. T., Wang, L. S. & Su, J. H., 8月 2021, 於: Metabolites. 11, 8, 532.

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4 引文斯高帕斯（Scopus）

Arenarosides A-G, Polyhydroxylated Oleanane-Type Saponins from Polycarpaea arenaria and their Cytotoxic and Antiangiogenic Activities

Nguyen, N. L., Vo, T. H., Lin, Y. C., Liaw, C. C., Lu, M. K., Cheng, J. J., Chen, M. C. & Kuo, Y. H., 2月 26 2021, 於: Journal of Natural Products. 84, 2, p. 259-267 9 p.

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3 引文斯高帕斯（Scopus）

Automatic detection of the circulating cell-free methylated DNA pattern of GCM2, ITPRIPL1 and CCDC181 for detection of early breast cancer and surgical treatment response

Wang, S. C., Liao, L. M., Ansar, M., Lin, S. Y., Hsu, W. W., Su, C. M., Chung, Y. M., Liu, C. C., Hung, C. S. & Lin, R. K., 3月 2021, 於: Cancers. 13, 6, p. 1-26 26 p., 1375.

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7 引文斯高帕斯（Scopus）

Butyrate modulates adipose-derived stem cells isolated from polygenic obese and diabetic mice to drive enhanced immunosuppression

Hsu, W. T., Huang, W. J., Chiang, B. L. & Tseng, P. H., 7月 2021, 於: Cytotherapy. 23, 7, p. 567-581 15 p.

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2 引文斯高帕斯（Scopus）

Compounds Isolated from Wikstroemia taiwanensis Regulate Bone Remodeling by Modulating Osteoblast and Osteoclast Activities

Imtiyaz, Z., Lin, Y. T., Liang, F. Y., Chiou, W. F. & Lee, M. H., 7月 13 2021, 於: Frontiers in Pharmacology. 12, 670254.

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Constituents of aquilaria sinensis leaves upregulate the expression of matrix metalloproteases 2 and 9

Hsiao, S. W., Wu, Y. C., Mei, H. C., Chen, Y. H., Hsiao, G. & Lee, C. K., 2021, 於: Molecules. 26, 9, 2537.

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1 引文斯高帕斯（Scopus）

Determination of phenylalanine enantiomers in the plasma and urine of mammals and ᴅ-amino acid oxidase deficient rodents using two-dimensional high-performance liquid chromatography

Hsiao, S-W., Ishii, C., Furusho, A., Hsieh, C-L., Shimizu, Y., Akita, T., Mita, M., Okamura, T., Konno, R., Ide, T., Lee, C-K. & Hamase, K., 1月 2021, 於: Biochimica et Biophysica Acta - Proteins and Proteomics. 1869, 1, p. 140540

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4 引文斯高帕斯（Scopus）

Development of a simple fluorescence sensing system for carbonyl stress in urine

Huang, W. J., Sun, Y. T., Lee, W. H., Lin, P. Y. & Chen, C. M., 2021, 於: Sensors and Materials. 33, 10, p. 3489-3497 9 p.

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Dibenzofuran, 4-chromanone, acetophenone, and dithiecine derivatives: Cytotoxic constituents from eupatorium fortunei

Chang, C. H., Wu, S., Hsu, K. C., Huang, W. J. & Chen, J. J., 7月 2021, 於: International journal of molecular sciences. 22, 14, 7448.

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3 引文斯高帕斯（Scopus）

Downregulation of gap junctional intercellular communication and connexin 43 expression by bisphenol A in human granulosa cells

Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 6月 2021, 於: Biotechnology and Applied Biochemistry. 68, 3, p. 676-682 7 p.

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4 引文斯高帕斯（Scopus）

Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

Mehndiratta, S., Chen, M. C., Chao, Y. H., Lee, C. H., Liou, J. P., Lai, M. J. & Lee, H. Y., 1月 1 2021, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 74-84 11 p.

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Effects of Neurofeedback on Fibromyalgia: A Randomized Controlled Trial

Wu, Y. L., Fang, S. C., Chen, S. C., Tai, C. J. & Tsai, P. S., 2021, (接受/付印) 於: Pain Management Nursing. 22, 6, p. 755-763 9 p.

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4 引文斯高帕斯（Scopus）

Efficacy of cinnamon patch treatment for alleviating symptoms of overactive bladder: A double-blind, randomized, placebo-controlled trial

Chen, L. L., Shen, Y. C., Ke, C. C., Imtiyaz, Z., Chen, H. I., Chang, C. H. & Lee, M. H., 1月 2021, 於: Phytomedicine. 80, 153380.

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6 引文斯高帕斯（Scopus）

Eps15 homology domain-containing protein 3 hypermethylation as a prognostic and predictive marker for colorectal cancer

Wang, Y. H., Chang, S. C., Ansar, M., Hung, C. S. & Lin, R. K., 5月 2021, 於: Biomedicines. 9, 5, 453.

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Fast dereplication of xanthine oxidase-inhibiting compounds in alfalfa using comparative metabolomics

Hsu, S. J., Verpoorte, R., Lin, S. M. & Lee, C. K., 3月 2021, 於: Food Research International. 141, 110170.

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8 引文斯高帕斯（Scopus）

Hydrolysable tannins exhibit acetylcholinesterase inhibitory and anti-glycation activities in vitro and learning and memory function improvements in scopolamine-induced amnesiac mice

Chen, L. G., Lin, S. Y., Lee, Y. S., Wang, C. C. & Hou, W. C., 8月 2021, 於: Biomedicines. 9, 8, 1066.

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2 引文斯高帕斯（Scopus）

Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

Chao, M. W., Lin, T. E., HuangFu, W. C., Chang, C. D., Tu, H. J., Chen, L. C., Yen, S. C., Sung, T. Y., Huang, W. J., Yang, C. R., Pan, S. L. & Hsu, K. C., 12月 2021, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 98-108 11 p.

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4 引文斯高帕斯（Scopus）

In situ subcutaneously injectable thermosensitive PEG-PLGA diblock and PLGA-PEG-PLGA triblock copolymer composite as sustained delivery of bispecific anti-CD3 scFv T-cell/anti-EGFR Fab Engager (BiTEE)

Wei, P. S., Chen, Y. J., Lin, S. Y., Chuang, K. H., Sheu, M. T. & Ho, H. O., 11月 2021, 於: Biomaterials. 278, 121166.

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8 引文斯高帕斯（Scopus）

Interleukin-33 promotes invasiveness of human ovarian endometriotic stromal cells through the ST2/MAPK/MMP-9 pathway activated by 17β-estradiol

Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 7月 2021, 於: Taiwanese Journal of Obstetrics and Gynecology. 60, 4, p. 658-664 7 p.

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2 引文斯高帕斯（Scopus）

Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia

Yen, S. C., Chen, L. C., Huang, H. L., Ngo, S. T., Wu, Y. W., Lin, T. E., Sung, T. Y., Lien, S. T., Tseng, H. J., Pan, S. L., Huang, W. J. & Hsu, K. C., 1月 22 2021, 於: Journal of Natural Products. 84, 1, p. 1-10 10 p.

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11 引文斯高帕斯（Scopus）

In vivo and in vitro evaluation of the osteogenic potential of Davallia mariesii T. Moore ex Baker

Lin, Y. T., Peng, S. W., Imtiyaz, Z., Ho, C. W., Chiou, W. F. & Lee, M. H., 1月 10 2021, 於: Journal of Ethnopharmacology. 264, 113126.

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Isomalabaricane Triterpenes from the Marine Sponge Rhabdastrella sp

Lai, K. H., Huang, Z. H., El-Shazly, M., Peng, B. R., Wei, W. C. & Su, J. H., 4月 6 2021, 於: Marine Drugs. 19, 4, 206.

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6 引文斯高帕斯（Scopus）

Lophatherum gracile Brongn. attenuates neutrophilic inflammation through inhibition of JNK and calcium

Lai, K. H., Chen, P. J., Chen, C. C., Yang, S. H., El-Shazly, M., Chang, Y. C., Wu, Y. H., Wu, Y. H., Wang, Y. H., Hsieh, H. L. & Hwang, T. L., 1月 10 2021, 於: Journal of Ethnopharmacology. 264, 113224.

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13 引文斯高帕斯（Scopus）

Maternal immune activation causes social behavior deficits and hypomyelination in male rat offspring with an autism-like microbiota profile

Lee, G. A., Lin, Y. K., Lai, J. H., Lo, Y. C., Yang, Y. C. S. H., Ye, S. Y., Lee, C. J., Wang, C. C., Chiang, Y. H. & Tseng, S. H., 8月 2021, 於: Brain Sciences. 11, 8, 1085.

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17 引文斯高帕斯（Scopus）

Monosaccharide Composition Analysis of Immunostimulating Subfraction from Auricularia auricula-judae Hot Water Extract

Chung, H. C., Hsu, S. J., Yu, Z. R., Lee, C. K., Wang, B. J. & Lin, S. M., 12月 2021, 於: Taiwanese Journal of Agricultural Chemistry and Food Science. 59, 4, p. 118-129 12 p.

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Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis

Wu, Y. Y., Hsieh, C. C., Li, C. Y., Chang, W. H., Chen, J. J., Lai, K. H., Wen, Z. H. & Chung, H. M., 11月 2021, 於: Natural Product Communications. 16, 11

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1 引文斯高帕斯（Scopus）

One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration

Wu, M. H., Wang, W., Chao, F. C., Hsieh, C. M., Chen, L. C., Lin, H. L., Ho, H. O., Huang, T. J. & Sheu, M. T., 2月 2021, 於: Carbohydrate Polymers. 254, 117270.

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2 引文斯高帕斯（Scopus）

Phase I Dose-Escalation Study of SCB01A, a Microtubule Inhibitor with Vascular Disrupting Activity, in Patients with Advanced Solid Tumors

Shiah, H. S., Chiang, N. J., Lin, C. C., Yen, C. J., Tsai, H. J., Wu, S. Y., Su, W. C., Chang, K. Y., Wang, C. C., Chang, J. Y. & Chen, L. T., 4月 2021, 於: Oncologist. 26, 4, p. e567-e579

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